Tizanidine, also sold under the trade names Zanaflex and Sirdalud (Sun Pharma) among several others, is a short acting muscle relaxer. It falls under the pain relief category of drugs as it functions by obstructing nerve impulses (pain sensations) that are sent to the brain. Tizanidine temporarily relaxes muscle tone and is used primarily in the treatment of spasticity caused by certain conditions (multiple sclerosis, spinal cord injury). This medication may also be used for conditions not listed here.
Important Information about Tizanidine
Tizanidine pain relief medication (Zanaflex, Sirdalud) is a short acting drug that should be used only for day to day activities that need relief from muscle spasticity. Do not take this medication if you are also taking antidepressant fluvoxamine, or antibiotic ciprofloxacin. Also do not take Tizanidine at a time when muscle tone is highly required to ensure safe balance and movement for some activities. In some situations, reduced muscle tone can be dangerous and greatly impact your physical safety.
Changing the way you take Tizanidine (switching between tablets and capsules), or with regards to eating, can lead to side effects of this medication or reduction in its effectiveness. Always follow your doctor’s directions.
Do not take too much of Tizanidine medication in a 24 hour period (ask your doctor or pharmacist for the maximum limit per day) as it can cause liver damage. Some medications which cause sleepiness such as cold or allergy drugs, anti depressants, narcotic pain killers, sleeping pill, other muscle relaxers, and anti seizure medications can add to sleepiness caused by Tizanidine. Inform your doctor if you are using such medicines or need to use them. Avoid alcohol consumption as it can increase the chances of some of the side effects of this medicine.
Tizanidine is a FDA pregnancy category C drug. It may be harmful to an unborn baby if taken during pregnancy. Inform your doctor in advance if you are pregnant or planning to become pregnant. It is not known whether Tizanidine can pass into breast milk and harm a nursing baby. Do not take this medication without proper medical advice if you are breast feeding. Tizanidine may take much longer to clear from body of older adults. Hence they must carefully follow their doctor’s instructions with regards to dosing.
Before taking Tizanidine
Before taking Tizanidine pain relief medicine (Zanaflex, Sirdalud), remember to keep in mind all points and precautions mentioned above. Discuss them with your doctor and clarify all doubts, if any.
You must not take Tizanidine if you are allergic to it or if you are taking the antidepressant fluvoxamine, or the antibiotic ciprofloxacin. You must also notify your doctor in advance if you are suffering from any of these following conditions: liver or kidney disease, high or low blood pressure, or a history of Long QT syndrome. Having any of these conditions may make Tizanidine unsafe for you or you may be required special dose adjustments. Talk to your doctor about this.
How should I take Tizanidine?
Take Tizanidine pain relief medication exactly as directed by your doctor. All medications come with a patient leaflet with complete instructions and details. Refer it for any doubts. Do not alter the course of the medication in any way (do not take more or less than the prescribed dosage). Also do not take it after the period for which the medication was prescribed is over.
Take Tizanidine tablet with a full glass of water. It is a short acting drug which means its effects will be most noticeable between 1 and 6 hours after taking it. Allow 6 to 8 hours between two doses. You may experience withdrawal symptoms such as dizziness, increased heart rate, shaking, anxiety, and increased spasticity when you stop taking Tizanidine after a long period of use. Hence, a sudden discontinuation of this medication is not recommended. You may be advised to gradually decrease the dosage before you completely stop. Always store Tizanidine medication in a cool and dry place.
What if I forgot to take a dose of Tizanidine?
Do not miss a single dose of Tizanidine. However, if you miss a dose, take it as soon as your remember it. Do not take the missed dose if the time to take the next dose is almost up. Instead continue with the original schedule. Never take multiple doses closer to each other.
What to do in case of an Overdose?
In case of an overdose of Tizanidine, get emergency medical attention or call the Poison helpline at 1-800-222-1222. Overdose may lead to confusion, drowsiness, reduced heart rate, shortness of breath, light headedness, fainting, or coma.
Things and Activities to avoid while taking Tizanidine
Tizanidine can impact your thinking capability and reflexes. Be careful if you indulge in activities which require a high degree of mental awareness and thinking such as driving or handling heavy equipment. Do not get up suddenly from a lying or sitting position as it may cause dizziness or you may fall. Avoid alcohol consumption while taking this medication. Also avoid taking other medications that cause sleepiness. Consult your doctor about this.
Tizanidine Side Effects
Some common side effects of Tizanidine are dry mouth, drowsiness, light headedness, constipation, weakness, or tiredness. If any of these conditions persist or worsen, contact your doctor immediately.
Tizanidine has caused (very rarely) liver disease in some people. If you experience any symptoms which signal liver damage (persistent nausea or vomiting, severe stomach or abdominal pain, dark urine,or jaundice (yellowing of eyes/skin)). Some other serious side effects due to Tizanidine are fainting, mood or behavior changes, vision changes, or slow/irregular heartbeat.
These are not all the possible side effects of Tizanidine. There may be others. If you experience any serious side effects, stop taking Tizanidine and seek emergency medical attention. You may also report your side effects to FDA by calling their toll free number 1-800-FDA-1088.
Tizanidine Dosing Information
Your Tizanidine dosage will be decided by your doctor after examining you thoroughly. Dosage may depend on several factors like age, seriousness of the conditions, other conditions, and allergies among several others.
Interaction with other drugs
Certain drugs can interact with Tizanidine. You may not be able to take Tizanidine or may need special dose adjustments if you are taking any of these medications already: cimetidine, acyclovir, famotidine, ticlopidine, zileuton, birth control pills, certain antibiotics (enoxacin, levofloxacin, moxifloxacin, ofloxacin, or others), blood pressure medications (clonidine, guanabenz, guanfacine, or methyldopa), or anti arrhythmics (amidarone, mexiletine, propafenone, or verapamil). Notify your doctor if you use any of these medicines already. Also let your doctor know about any other medicines or related products which you may be using. Never start taking a new medicine without proper medical advice.
|US Brand Name||Zanaflex|
|Generic Name||Tizanidine HCl|