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Sirdalud - 2mg

Quick Overview

What is the most important information I should know about tizanidine?


• Use caution when driving, operating machinery, or performing other hazardous activities. Tizanidine may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities.
• Dizziness is most likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
• Use caution with alcohol, other muscle relaxants, sleep or anxiety medicines, and pain medicines. These drugs may increase drowsiness and dizziness while you are taking tizanidine. Do not take any other medicine during treatment with tizanidine without first talking to your doctor or pharmacist.


What is tizanidine?


• Tizanidine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
• Tizanidine is used to treat increased muscle tone associated with spasticity.
• Tizanidine may also be used for purposes other than those listed in this medication guide.


Who should not take tizanidine?


• Before taking this medication, tell your doctor if you
· have liver disease,
· have kidney disease,
· have low blood pressure or if you are on medication to treat high blood pressure; or
· are taking birth control pills.
• You may not be able to take tizanidine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
• Tizanidine is in the FDA pregnancy C. This means that it is not known whether tizanidine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
• It is not known whether tizanidine passes into breast milk. Do not take tizanidine without first talking to your doctor if you are breast-feeding a baby.


How should I take tizanidine?


• Take tizanidine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Tizanidine is usually taken several times a day. Follow your doctor's instructions.
• Do not take more than three doses of tizanidine--or more than 36 mg--in 24 hours. Too much of this medication can damage your liver.
• Store tizanidine at room temperature away from moisture and heat.


What happens if I miss a dose?


• Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take your next regularly scheduled dose. Do not take a double dose of this medication.


 


What happens if I overdose?


• Seek emergency medical attention.
• Symptoms of a tizanidine overdose are not well known but include unconsciousness and irregular breathing.


What should I avoid while taking tizanidine?


• Use caution when driving, operating machinery, or performing other hazardous activities. Tizanidine may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities.
• Dizziness is most likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
• Use caution with alcohol, other muscle relaxants, sleep or anxiety medicines, and pain medicines. These drugs may increase drowsiness and dizziness while you are taking tizanidine. Do not take any other medicine during treatment with tizanidine without first talking to your doctor or pharmacist.


 


What are the possible side effects of tizanidine?


• If you experience any of the following serious side effects, stop taking tizanidine and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
· hallucinations or abnormal behavior; or
· liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
• Other, less serious side effects may be more likely to occur. Continue to take tizanidine and talk to your doctor if you experience
· drowsiness or dizziness;
· weakness;
· dry mouth;
· increased muscle tone or spasms; or
· sweating.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


 


What other drugs will affect tizanidine?


• Tizanidine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.
• Birth control pills can increase the effects of tizanidine. Tell your doctor if you are taking birth control pills before starting treatment with tizanidine.
• Tizanidine may lower blood pressure. Tell your doctor if you are taking another medicine to lower blood pressure or a medicine to treat another heart condition.
• Drugs other than those listed here may also interact with tizanidine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.


 


Where can I get more information?


• Your pharmacist has additional information about tizanidine written for health professionals that you may read.


 

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Details

What is Tizanidine?
Tizanidine, also sold under the trade names Zanaflex and Sirdalud (Sun Pharma) among several others, is a short acting muscle relaxer. It falls under the pain relief category of drugs as it functions by obstructing nerve impulses (pain sensations) that are sent to the brain. Tizanidine temporarily relaxes muscle tone and is used primarily in the treatment of spasticity caused by certain conditions (multiple sclerosis, spinal cord injury). This medication may also be used for conditions not listed here.

Important Information about Tizanidine
Tizanidine pain relief medication (Zanaflex, Sirdalud) is a short acting drug that should be used only for day to day activities that need relief from muscle spasticity. Do not take this medication if you are also taking antidepressant fluvoxamine, or antibiotic ciprofloxacin. Also do not take Tizanidine at a time when muscle tone is highly required to ensure safe balance and movement for some activities. In some situations, reduced muscle tone can be dangerous and greatly impact your physical safety.
Changing the way you take Tizanidine (switching between tablets and capsules), or with regards to eating, can lead to side effects of this medication or reduction in its effectiveness. Always follow your doctor’s directions.
Do not take too much of Tizanidine medication in a 24 hour period (ask your doctor or pharmacist for the maximum limit per day) as it can cause liver damage. Some medications which cause sleepiness such as cold or allergy drugs, anti depressants, narcotic pain killers, sleeping pill, other muscle relaxers, and anti seizure medications can add to sleepiness caused by Tizanidine. Inform your doctor if you are using such medicines or need to use them. Avoid alcohol consumption as it can increase the chances of some of the side effects of this medicine.
Tizanidine is a FDA pregnancy category C drug. It may be harmful to an unborn baby if taken during pregnancy. Inform your doctor in advance if you are pregnant or planning to become pregnant. It is not known whether Tizanidine can pass into breast milk and harm a nursing baby. Do not take this medication without proper medical advice if you are breast feeding. Tizanidine may take much longer to clear from body of older adults. Hence they must carefully follow their doctor’s instructions with regards to dosing.

Before taking Tizanidine
Before taking Tizanidine pain relief medicine (Zanaflex, Sirdalud), remember to keep in mind all points and precautions mentioned above. Discuss them with your doctor and clarify all doubts, if any.
You must not take Tizanidine if you are allergic to it or if you are taking the antidepressant fluvoxamine, or the antibiotic ciprofloxacin. You must also notify your doctor in advance if you are suffering from any of these following conditions: liver or kidney disease, high or low blood pressure, or a history of Long QT syndrome. Having any of these conditions may make Tizanidine unsafe for you or you may be required special dose adjustments. Talk to your doctor about this.

How should I take Tizanidine?
Take Tizanidine pain relief medication exactly as directed by your doctor. All medications come with a patient leaflet with complete instructions and details. Refer it for any doubts. Do not alter the course of the medication in any way (do not take more or less than the prescribed dosage). Also do not take it after the period for which the medication was prescribed is over.
Take Tizanidine tablet with a full glass of water. It is a short acting drug which means its effects will be most noticeable between 1 and 6 hours after taking it. Allow 6 to 8 hours between two doses. You may experience withdrawal symptoms such as dizziness, increased heart rate, shaking, anxiety, and increased spasticity when you stop taking Tizanidine after a long period of use. Hence, a sudden discontinuation of this medication is not recommended. You may be advised to gradually decrease the dosage before you completely stop. Always store Tizanidine medication in a cool and dry place.

What if I forgot to take a dose of Tizanidine?
Do not miss a single dose of Tizanidine. However, if you miss a dose, take it as soon as your remember it. Do not take the missed dose if the time to take the next dose is almost up. Instead continue with the original schedule. Never take multiple doses closer to each other.

What to do in case of an Overdose?
In case of an overdose of Tizanidine, get emergency medical attention or call the Doctor immediately. Overdose may lead to confusion, drowsiness, reduced heart rate, shortness of breath, light headedness, fainting, or coma.

Things and Activities to avoid while taking Tizanidine
Tizanidine can impact your thinking capability and reflexes. Be careful if you indulge in activities which require a high degree of mental awareness and thinking such as driving or handling heavy equipment. Do not get up suddenly from a lying or sitting position as it may cause dizziness or you may fall. Avoid alcohol consumption while taking this medication. Also avoid taking other medications that cause sleepiness. Consult your doctor about this.

Tizanidine Side Effects
Some common side effects of Tizanidine are dry mouth, drowsiness, light headedness, constipation, weakness, or tiredness. If any of these conditions persist or worsen, contact your doctor immediately.
Tizanidine has caused (very rarely) liver disease in some people. If you experience any symptoms which signal liver damage (persistent nausea or vomiting, severe stomach or abdominal pain, dark urine,or jaundice (yellowing of eyes/skin)). Some other serious side effects due to Tizanidine are fainting, mood or behavior changes, vision changes, or slow/irregular heartbeat.
These are not all the possible side effects of Tizanidine. There may be others. If you experience any serious side effects, stop taking Tizanidine and seek emergency medical attention. 

Tizanidine Dosing Information
Your Tizanidine dosage will be decided by your doctor after examining you thoroughly. Dosage may depend on several factors like age, seriousness of the conditions, other conditions, and allergies among several others.

Interaction with other drugs
Certain drugs can interact with Tizanidine. You may not be able to take Tizanidine or may need special dose adjustments if you are taking any of these medications already: cimetidine, acyclovir, famotidine, ticlopidine, zileuton, birth control pills, certain antibiotics (enoxacin, levofloxacin, moxifloxacin, ofloxacin, or others), blood pressure medications (clonidine, guanabenz, guanfacine, or methyldopa), or anti arrhythmics (amidarone, mexiletine, propafenone, or verapamil). Notify your doctor if you use any of these medicines already. Also let your doctor know about any other medicines or related products which you may be using. Never start taking a new medicine without proper medical advice.

Additional Information

SKU 1128
Stock Status N/A
US Brand Name Zanaflex
Strength 2mg
Generic Name Tizanidine HCl
Pharmaceutical Form Tablet/s
Manufacturer Sun Pharma, India
Shipped From India

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