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About the drug:
It is a Bacteriostatic as well as bacteriocidal antibiotic medication that is used for the treatment of tuberculosis, as a combination drug that along with Rifampicin.
Uses of the drug:
Pyrazinamide is an antibiotic medication prescribed mainly for the treatment of tuberculosis (TB). It may also be used for treatment of other infections. Pyrazinamide is available under several trade names, one of which is Pyzina (made by Lupin).
Working of the drug:
It acts against bacteria by killing them. This antibiotic slows down the growth or reproduction of the bacteria. It does that by inhibiting the cell wall synthesis.
Pyzina products are manufactured by Lupin, a leading pharmaceutical company. The products are available in various pack sizes on our website like: 30, 60 and 90 tablets.
Dosage form and strengths:
The following strengths of the combination product are available:
- Pyzina 500 mg
- Pyzina 750 mg
You can buy Pyzina 500 mg online on alldaychemist.com.
Before you take the drug:
Do not take this drug if you:
- Are allergic to penicillin or amoxicillin or any other antibiotic
- Have a history of allergies
- Are pregnant or planning to have a baby
- Are a breastfeeding mother as the drug may pass into the mother’s milk
- Have or ever had kidney problems or any kind of liver problems
- Have asthma or hay fever
Tell your doctor if you:
Are taking oral contraceptives as this drug may inhibit the action the oral contraceptives. So, consult your doctor about that too.
Are below 16 years of age
How much to take?
Dosage depends upon your age, weight, medical condition and your response to the treatment. Hence doctor will decide your dose. Take the dose exactly as prescribed by the doctor.
How to take?
Take Pyrazinamide strictly as prescribed by your doctor. Do not make any changes in using the medication without his or her advice. All medications come with a patient leaflet. Follow the instructions in them if you have any doubt. However, remember that your doctor's advice overrides everything else.
For how long to take it?
You should take the dose until you finish the prescription. Do not change the dose or stop it even if you feel better. You should complete the dose. Penicillin G potassium should be taken until the full course completes so as the infection ceases out completely.
Overdose may cause unwanted effects. You may require urgent medical help in this situation. In such a case visit the nearest healthcare center or call your doctor immediately.
Don't miss a single dose of Pyrazinamide. But if you do miss a dose for some reasons, take it as soon as you remember it. However, forget about the missed dose if the time for the next dose is near. Don't take multiple doses close to each other to compensate for the missed dose as that will lead to extra medicine in your body at one time which can be dangerous.
Side effects of the drug:
Pyrazinamide (Pyzina) like all medications can cause side effects. However, not all people who take it will experience a side effect. Side effects of this medication include fever, nausea, vomiting, loss of appetite, yellow skin or eyes, dark urine, difficult or painful urination, painful or swollen joints, worsening gout, and a rash. If you feel that you have got a serious side effect due to this medication, get medical help right away.
The side effects mentioned above are non exhaustive and there may be other side effects as well. Seek medical help if you witness any other severe side effects.
Common drug interactions:
There are some drugs which can interact with Pyrazinamide or vice versa. This medication can reduce the effects of allopurinol. Let your doctor know in advance if you are using this medication or any other medicines. Pyrazinamide may also affect Acetest and Ketostix urine tests for ketones.
Drugs other than those mentioned here may also interact with Pyrazinamide. Do not start a new medication without going to a doctor or without proper medical advice.
So it is necessary to consult your doctor about the following drugs such as:
- Typhoid Vaccine Live
- BCG Vaccine Live
Things to remember:
- Pyrazinamide (Pyzina) is a prescription-only drug and available only with a doctor's prescription
- Do not use this medication for any other infection without referring to the doctor.
- Do not freeze the medicine and store the medicine at room temperature
- In case you do not feel comfort after completing the dose prescribed by the doctor then consult with your doctor immediately
- The safety and efficacy of this drug is not established in children below 16 years of age