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Trental 400mg

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Trental

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SKU 788
Generic Name Pentoxifylline
Manufacturer Aventis, India
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About the drug

The main active constituent present in this drug is Pentoxifylline which is a  methylxanthine derivative that hinders the activity of the enzyme  phosphodiesterase and affects blood rheology. It improves blood flow by increasing the flexibility of red blood cells (erythrocytes) and white blood cells (leukocyte). It also prevents platelet aggregation. This drug is used to relieve muscle pain in people with peripheral artery disease. It is a generic drug, and is sold under many brand names all over the world.

Uses of the drug

Trental is used for the treatment of patients with intermittent claudication wherein there is chronic occlusion of the arteries of the limbs. Trental can improve functions and symptoms, but is not proposed to substitute more definitive treatment, such as surgical bypass, removal of arterial blockages during the treatment of peripheral vascular disease.

Working of the drug

It contains one active ingredient Pentoxifylline which is a xanthine derivative.

Pentoxifylline

Pentoxifylline improves the flow of blood by decreasing its viscosity. In patients with chronic peripheral arterial disease, this increases blood flow to the affected microcirculation and enhances tissue oxygenation. Pentoxifylline administration has been shown to produce dose-related hemorrheologic effects, lowering blood viscosity, and improving erythrocyte flexibility.

Manufacturer

Trental is manufactured by Aventis Pharmaceutical, a pharmaceutical giant. It is available on our website and you can buy Trental online from alldaychemist.com.

Dosage form and strength

Trental is available in the strength combination of 400 mg having an active ingredient Pentoxifylline in it. You can buy Trental 400 mg online, visit alldaychemist.com where you’ll get medicines at the best deal.

Before taking the drug

Before taking pentoxifylline, tell your doctor or pharmacist:

  • If you are allergic to it; or to caffeine, or theophylline; or if you have any other allergies
  • If you had a recent stroke, recent bleeding in the eye, kidney problems, liver problems, recent major surgery, stomach ulcer
  • If you’re pregnant, breast-feed or planning to get pregnant

Dosage:

How much to take the drug?

Take this medication by mouth with food, usually 3 times daily or as directed by your doctor.

Dosage is based on your medical condition and response to treatment. Do not stop this medication without consulting your doctor. Improvement in symptoms can occur in 2-4 weeks, but it may take up to 8 weeks to get the full benefit.

How to take the drug?

Take this medication by mouth with food, usually 3 times daily or as directed by your doctor.

Do not chew or crush this drug as doing so can release the entire drug at once, thereby, increasing your risk of side effects. Moreover, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet at once.

For how long to take it?

Do not stop taking Trental or change the dose without consulting with your doctor. This medication is meant to be taken on a regular basis, so take the drug as long as suggested by the doctor.

Overdose:

If you overdose, talk to your doctor or poisons information center for instructions. Take medical help as soon as possible.

Miss dose:

If you miss a dose, take it as soon as you remember. Skip the missed dose and resume your usual dosing schedule, if it is almost time for the next dose. Don’t take an extra dose in order to catch up.

Side effects of the drug

The less common effects of this drug include dizziness, headache, nausea or vomiting and stomach discomfort.

Chest pain and irregular heartbeat are some of the rare side-effects of the drug.

Consult your doctor immediately, if any of these side effects occur while taking this drug.

Common drug interactions

Some drugs may interact with this drug and produce some unwanted effects. These drugs include drugs that cause thinning of the blood such as dabigatran or warfarin, drugs that can cause bleeding or bruising (including antiplatelet drugs such as clopidogrel), theophylline, NSAIDs such as ketorolac, ibuprofen, or naproxen and,.

Warning:

Things to remember:

  • Don’t use expired drugs.
  • Always take the medicine as prescribed by the doctor.
  • Keep a complete record of all the medicines you are taking along with this drug.
Trental 400mg
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