Arthrotec 50mg/200mcg
Out Of Stock
| SKU: | 318 |
|---|---|
| Active Ingredient: | Diclofenac Sodium - Misoprostol |
| Manufacturer: | Pharmacia, UK |
Buy Arthrotec 50mg/200mcg (Diclofenac Sodium - Misoprostol) Online
About the drug:
Arthrotec (Diclofenac Sodium/Misoprostol) is a combination drug that contains an NSAID or nonsteroidal anti-inflammatory drug (Diclofenac sodium) which lowers pain and inflammation causing substances in the body and Misoprostol that is a prostaglandin analog which protects the mucosal lining of the Gastrointestinal tract.
Uses of the drug:
It is prescribed or used mainly for the treatment of rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis. The drug is used for the treatment of different kinds of pains present in different parts of the body.
Manufacturer:
There are various trade names under which diclofenac sodium is sold in the market. Arthrotecc-50 mg/200mcg is manufactured by Pharmacia, U.K.. You can easily buy Arthrotecc-50 mg/200mcg online at alldaychemist.com at very cheap rates.
Dosage forms and strengths:
Diclofenac Sodium and Misoprostol combination drug is available on our website in the form of tablets under the trade name-Arthrotec. There are two different strengths of this drug available on our website:
• Arthrotec- 50mg/200mcg
• Arthrotec- 70mg/200mcg
Before you take the drug:
• Do not take if:
You have ever had a heart attack or any bypass surgery
You are allergic to it or if you have allergies towards other NSAIDs like aspirin and others.
You have any of these conditions: asthma; polyps in your nose; Porphyria; bleeding or blood clotting disorder
You smoke
If you have a history of heart attack, stroke, or blood clot; liver or kidney disease; heart disease, congestive heart failure, high blood pressure, or a history of stomach ulcers or bleeding.
• Tell your doctor if:
You are pregnant or planning to be a mother as Diclofenac Sodium is an FDA pregnancy category-D drug. This medication has the potential to harm an unborn baby if taken while being pregnant
You are breast feeding. It is not known if Diclofenac Sodium can pass into breast milk and harm a nursing baby
You are taking any other pain reliever drug
Dosage:
• How much to take the drug?
Only doctor will decide the best suitable dose according to your age, gender and condition.The dose will be different for rheumatoid arthritis and osteoarthritis. Take the tablets strictly according to your doctor’s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this medication after the prescribed period is over.
• How to take the drug?
Avoid crushing, breaking, or chewing the tablet as doing so may lead to too much of the medicine to be released at once. Instead, swallow it whole with a glassful of water. There is no limitation regarding food, so the tablet can be taken on an empty stomach as well as with food.
• For how long to take it?
Take the medication as long as the doctor prescribes you to take it as it will help to ease the problem more swiftly. Completing the dose is very important. You can easily buy Arthrotec 50mg/200mcg online from alldaychemist.com at very cheap rates.
• Overdose:
Overdose may lead to drowsiness, muscle weakness, nausea, vomiting, stomach pain, shortness of breath, lightheadedness, or fainting. In case of an overdose of Diclofenac Sodium, get emergency medical attention or call the nearest health care center immediately.
• Miss dose:
If you miss a dose of Diclofenac Sodium medication, take it as soon as you remember. Don’t take the missed dose if the time to take the next dose is almost up. Taking multiple doses near to each other can lead to excess medication in your body which can be harmful.
Side effects of the drug:
You must seek emergency medical attention if you have chest pain, weakness, shortness of breath, slurred speech, or difficulties in vision or balance after taking Diclofenac Sodium/Misoprostol. The drug may also impact your stomach or intestines severely by causing bleeding or perforation in them. Inform your doctor right away if you witness symptoms of stomach and intestinal bleeding, such as stools which are black, bloody, or tarry in appearance; bloody cough or vomit that resembles coffee grounds.
You must not get worried as you may or may not experience these side-effects. In case you feel any discomfort, contact your healthcare center immediately.
Common drug interactions:
Read the medicine labels carefully and avoid other medicines that contain NSAIDs while taking this drug. Let your doctor know in advance if you are using any of these interacting drugs presently: Blood thinner like:
• Warfarin
• Cyclosporine
• Digoxin
• Diuretic
• Insulin or oral diabetes medications, Isoniazid, Pronbenecid, Rifampin, Secobarbital, Teniposide etc.
The drugs mentioned here are not the only ones that can interact with Diclofenac Sodium/Misoprostol. There may be others as well. Share the list of all types of medications and related products which you are using with your doctor and never start a new medication without his or her advice.
Warning:
Things to remember:
Alcohol consumption is also not recommended while taking Diclofenac Sodium
Diclofenac Sodium is not recommended for children younger than 18 years of age without proper medical advice
Stick to your doctor’s prescription strictly
What is Arthrotec 50mg/200mcg used for?
Arthrotec 50mg/200mcg is a combination tablet containing diclofenac Sodiumium 50mg (an NSAID for pain and inflammation) and misoprostol 200mcg (a synthetic prostaglandin E1 analogue that protects the stomach lining). It is prescribed for patients with osteoarthritis or rheumatoid arthritis who require diclofenac therapy but are at high risk of developing NSAID-induced gastric or duodenal ulcers. By combining pain relief and gastroprotection in a single tablet, Arthrotec improves compliance and reduces the risk of serious gastrointestinal complications in arthritis patients across the USA, UK, and Australia.
How does Arthrotec 50mg/200mcg work?
Arthrotec 50mg/200mcg combines two medicines that work together to manage arthritis pain while helping protect the stomach. Diclofenac reduces pain, swelling, stiffness, and inflammation in the joints by blocking substances that cause inflammation. Misoprostol helps protect the stomach lining by increasing mucus production, improving blood flow, and lowering stomach acid levels. This combination helps lower the risk of stomach ulcers, irritation, and bleeding that can sometimes occur with long-term use of anti-inflammatory pain medicines.
What is the recommended dosage for Arthrotec 50mg/200mcg?
The standard dose of Arthrotec 50mg/200mcg is one tablet taken two to three times daily with food. Taking it with meals reduces gastrointestinal side effects from misoprostol (diarrhoea and abdominal cramping) and enhances tolerability. The maximum daily dose should not exceed diclofenac 150mg/day in standard clinical practice. Duration of therapy is determined by the prescribing rheumatologist or physician based on disease activity and tolerability. Doses should be taken at evenly spaced intervals. Never split, crush, or chew the tablet — the misoprostol is integrated into the tablet core and must be swallowed whole.
Should Arthrotec 50mg/200mcg be taken with or without food?
Arthrotec 50mg/200mcg should always be taken with food. The misoprostol component causes dose-related gastrointestinal side effects — particularly diarrhoea and abdominal cramping — that are significantly reduced when taken with meals. Taking the tablet on an empty stomach increases the peak plasma concentration of misoprostol and worsens these effects. Avoid antacids containing magnesium (e.g., magnesium hydroxide) with Arthrotec, as they can worsen misoprostol-related diarrhoea. Schedule each dose with breakfast, lunch, or dinner. Consistent meal timing also helps maintain stable diclofenac plasma levels for sustained anti-inflammatory effect.
Is Arthrotec 50mg/200mcg safe for long-term use?
Arthrotec 50mg/200mcg can be used for extended periods under medical supervision but carries the standard long-term risks of NSAID therapy: cardiovascular effects (increased risk of MI and stroke with prolonged high-dose use), renal impairment, hypertension, and fluid retention. The misoprostol component significantly reduces — but does not eliminate — the risk of gastric ulceration. Cardiovascular risk increases with dose and duration, particularly in patients with pre-existing heart disease. Regular monitoring of renal function, blood pressure, and cardiovascular status is essential during long-term Arthrotec use. Lowest effective dose for the shortest necessary duration is recommended.
Who should avoid taking Arthrotec 50mg/200mcg?
Arthrotec 50mg/200mcg is absolutely contraindicated in pregnant women — misoprostol causes uterine contractions and can induce abortion, premature labour, or fetal harm. It is also contraindicated in patients with known hypersensitivity to diclofenac or other NSAIDs (including aspirin-induced asthma, urticaria, or rhinitis), active gastrointestinal ulceration or bleeding, severe heart failure, severe renal or hepatic impairment, and in the peri-operative period of coronary artery bypass graft surgery. Women of childbearing potential must use reliable contraception throughout Arthrotec therapy. Elderly patients require careful cardiovascular and renal monitoring.
How does Arthrotec 50mg/200mcg compare to taking diclofenac alone?
Taking diclofenac alone without gastroprotection significantly increases the risk of NSAID-induced peptic ulcers, gastric erosions, and gastrointestinal bleeding — particularly in older patients and those with prior ulcer history. Arthrotec 50mg/200mcg integrates misoprostol directly into the diclofenac tablet, ensuring gastroprotection is taken consistently with each NSAID dose. Studies show Arthrotec reduces the incidence of endoscopically confirmed ulcers by 50–80% compared to diclofenac alone. Separate prescribing of a PPI with diclofenac is an alternative, but Arthrotec's combination simplifies the regimen and ensures compliance with gastroprotective therapy.
Is Arthrotec 50mg/200mcg better than Arthrotec 75mg/200mcg?
Arthrotec 50mg/200mcg and 75mg/200mcg contain the same dose of misoprostol but differ in diclofenac dose. The 50mg strength is preferred for patients requiring moderate anti-inflammatory dosing — typically in osteoarthritis — where three daily doses provide 150mg total diclofenac. The 75mg strength is typically dosed twice daily, also delivering 150mg total diclofenac, and is preferred in rheumatoid arthritis or when twice-daily dosing improves compliance. If adequate pain control is achieved with Arthrotec 50mg, there is no benefit in switching to the higher strength. Clinical response and tolerability guide the choice between the two.
Can I buy Arthrotec 50mg/200mcg from AllDayChemist?
Yes, Arthrotec 50mg/200mcg is available at AllDayChemist, serving patients in the USA, UK, Australia, and most of the countries since 2002. Arthrotec can be expensive at retail pharmacies, particularly branded versions in the USA. AllDayChemist sources authentic diclofenac/misoprostol combination tablets from licensed manufacturers at competitive prices. Discreet packaging and worldwide tracked shipping are standard. Important: Arthrotec is a prescription medication and is absolutely contraindicated in pregnancy — AllDayChemist advises customers to consult their physician and confirm eligibility before ordering this medication.
Is Arthrotec 50mg/200mcg cheaper at AllDayChemist than US pharmacies?
Arthrotec 50mg/200mcg is substantially more affordable at AllDayChemist than at US retail pharmacies, where branded Arthrotec carries a significant premium. AllDayChemist's direct manufacturer sourcing and international supply chain allow competitive pricing on diclofenac/misoprostol combination tablets, making ongoing arthritis therapy more manageable for patients paying out-of-pocket. Combined with free worldwide shipping on qualifying orders and discreet packaging, AllDayChemist provides reliable access to this specialist combination NSAID for patients in the USA, UK, and Australia who need it long-term.
What are the side effects of Arthrotec 50mg/200mcg?
The most common side effects of Arthrotec 50mg/200mcg are gastrointestinal, primarily from misoprostol: diarrhoea (often within the first few weeks, affecting up to 20% of patients), abdominal cramping, nausea, dyspepsia, and flatulence. Taking the tablet with food significantly reduces these effects. Diclofenac-related side effects include fluid retention, elevated blood pressure, headache, dizziness, elevated liver enzymes, and rash. Serious but less common adverse effects include cardiovascular events (MI, stroke), renal impairment, severe hepatotoxicity, and severe cutaneous adverse reactions. Misoprostol-induced uterine contractions in women not known to be pregnant are a rare but serious complication.
Can Arthrotec 50mg/200mcg cause miscarriage?
Yes. Misoprostol in Arthrotec 50mg/200mcg is a potent uterotonic agent that causes uterine contractions. Even at the doses in Arthrotec, misoprostol can cause miscarriage, premature labour, or serious fetal abnormalities. Arthrotec is absolutely contraindicated in pregnancy and must not be taken by women who are or may become pregnant. Women of childbearing potential must use reliable contraception throughout treatment and discuss the necessity and timing of therapy with their physician. A negative pregnancy test is recommended before starting Arthrotec. This is a boxed (black box) warning in the USA and a major prescribing restriction in all countries where Arthrotec is licensed.
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