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Antibiotics

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  1. Pentids 400mg
    Pentids 400mg
    Rating:
    90%
    Generic For : Penicillin G
    Active Ingredients : Generic
    30 Tablet/s
    US$ 11.50
    19% OFF
  2. Nizonide 500mg
    Nizonide 500 mg
    Generic For : Alinia
    Active Ingredients : Nitazoxanide
    30 Tablet/s
    US$ 13.00
    29% OFF
  3. Martifur 100mg
    Martifur 100 mg
    Rating:
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    Generic For : Macrodantin
    Active Ingredients : Nitrofurantoin
    28  Tablet/s
    US$ 7.50
    33% OFF
  4. Cephadex 500mg
    Cephadex 500mg
    Rating:
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    Generic For : Keflex
    Active Ingredients : Cephalexin
    30 Tablet/s
    US$ 25.00
    21% OFF
  5. Ciplox 500mg
    Ciplox 500mg
    Generic For : Cipro
    Active Ingredients : Ciprofloxacin
    30 Tablet/s
    US$ 18.50
    23% OFF
  6. Ciplox 250mg
    Ciplox 250mg
    Rating:
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    Generic For : Cipro
    Active Ingredients : Ciprofloxacin
    30 Tablet/s
    US$ 13.00
    31% OFF
  7. Levoflox 500mg
    Levoflox 500mg
    Generic For : Levaquin
    Active Ingredients : Levofloxacin
    30 Tablet/s
    US$ 13.50
    18% OFF
  8. Flagyl 400mg
    Flagyl 400mg
    Generic For : Flagyl
    Active Ingredients : Metronidazole
    30 Tablet/s
    US$ 5.50
    39% OFF
  9. Phexin 250mg
    Phexin 250mg
    Generic For : Keflex
    Active Ingredients : Cephalexin
    30 Tablet/s
    US$ 16.00
    17% OFF
  10. Augmentin 1000mg (875+125)
    Augmentin 1000mg (875+125)
    Generic For : Augmentin
    Active Ingredients : Amoxicillin Clavulanic Acid
    30 Tablet/s
    US$ 55.00 US$ 91.99
    49% OFF
  11. Augmentin 625 Duo
    Augmentin 500 125mg
    Rating:
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    Generic For : Augmentin
    Active Ingredients : Amoxicillin Clavulanic Acid
    30 Tablet/s
    US$ 34.21 US$ 42.76
    20% OFF
  12. Topinate Cream 30gm
    Topinate 0.05% 30 gm
    Rating:
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    Generic For : Clobetasol
    Active Ingredients : Clobetasol Propionate
    1 Tube/s
    US$ 6.50
    44% OFF
  13. Bactrim DS
    Bactrim DS (800 + 160)mg
    Rating:
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    Generic For : Septra DS
    Active Ingredients : Sulphamethoxazole + Trimethoprim
    30 Tablet/s
    US$ 8.00
    35% OFF
  14. Azee 500mg
    Azee 500mg
    Rating:
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    Generic For : Zithromax
    Active Ingredients : Azithromycin
    5 Tablet/s
    US$ 9.72
    31% OFF
  15. Azee 250mg
    Azee 250mg
    Generic For : Zithromax
    Active Ingredients : Azithromycin
    30 Tablet/s
    US$ 25.50
    16% OFF
  16. Azee 100 DT
    Azee DT 100mg
    Generic For : Zithromax
    Active Ingredients : Azithromycin
    30 Tablet/s
    US$ 18.50
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  17. Azee 1000mg
    Azee 1000mg
    Rating:
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    Generic For : Zithromax
    Active Ingredients : Azithromycin
    6 Tablet/s
    US$ 11.11
    10% OFF
  18. Althrocin 500mg
    Althrocin 500 mg
    Rating:
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    Generic For : Ery Tab
    Active Ingredients : Erythromycin
    30 Tablet/s
    US$ 17.50
    21% OFF
  19. Minoz 100mg
    Minoz 100mg
    Rating:
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    Generic For : Minocin
    Active Ingredients : Minocycline HCL
    30 Tablet/s
    US$ 25.00
    6% OFF
  20. Erytop 20gm
    Erytop 1% Gel 20gm
    Generic For : Cleocin T
    Active Ingredients : Clindamycin Phosphate Gel
    1 Tube/s
    US$ 7.50
    43% OFF
  21. Dalacin C 150mg
    Dalacin C 150mg
    Rating:
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    Generic For : Cleocin
    Active Ingredients : Clindamycin HCl
    30 Capsules
    US$ 29.50
    14% OFF
  22. Doxt SL 100mg
    Dox T SL
    Generic For : Vibramycin
    Active Ingredients : Doxycycline 100mg / Lactic Acid 5 Billion Spores
    30 Capsules
    US$ 8.50
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  23. Itaspor 100mg
    Itaspor 100mg
    Generic For : Sporanox
    Active Ingredients : Itraconazole
    28  Capsule/s
    US$ 54.32
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  24. Farobact ER 300mg
    Farobact ER 300mg
    Generic For : Faropenem
    Active Ingredients : Faropenem
    Sold Out
  25. Cynomycin 100mg
    Cynomycin 100mg
    Generic For : Minocin
    Active Ingredients : Minocycline HCL
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  26. Itaspor 200mg
    Itaspor 200mg
    Generic For : Sporanox
    Active Ingredients : Itraconazole
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  27. Farobact 200mg
    Farobact 200mg
    Generic For : Faropenem
    Active Ingredients : Faropenem
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  28. T Bact 7.5 gm Cream
    T Bact 7.5 gm Cream
    Rating:
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    Generic For : Bactobran
    Active Ingredients : Mupirocin
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  29. Raxitid 150 mg
    Raxitid 150 mg
    Rating:
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    Generic For : Rulide
    Active Ingredients : Roxithromycin
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  30. Pyzina 750mg
    Pyzina 750mg
    Generic For : Pyzina
    Active Ingredients : Pyrazinamide
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More Information

Antibiotics are medicines that act on the infections caused by the bacteria. Though our immune system is well equipped with natural antibiotic elements that protect us from harmful bacteria, sometimes we need to depend on external antibiotics for relief. These medicines sometimes react negatively with our immune system that’s why a proper prescription is a must. If someone over uses or abuses these antibiotics, the bacteria will turn resilient to the effects and the antibiotic will render ineffective. Some of the antibiotics are known for creating side effects if not used in the prescribed doses. The side effects may vary from a minor fungal infection to diarrhea. So, it is extremely important to get a prescription before purchasing antibiotics online. Our site alldaychemist.com offers a wide range of antibiotics for which you can place orders online. Another thing that must be taken care of is; use of antibiotics by pregnant woman, a breastfeeding mother or a person suffering from kidney ailment should be done as directed by physician only.

Antibiotic is a chemical substance produced by a microorganism that inhibits the growth of or kills other microorganisms especially bacteria and fungi.

Illnesses such as syphilis, tuberculosis, salmonella, and some forms of meningitis are caused by bacteria and are treated by antibiotics. The earliest account of the usage of microbes against microbes was laid by Fleming. Fleming (1928) described the effect on staphylococci of a substance produced by Penicillium notatum and researched its possible use as a treatment for bacterial infections.

The noun “antibiotic” was first used in 1942 by Dr. Selman A. Waksman, soil microbiologist. Dr. Waksman and his colleagues discovered several Actinomycetes derived antibiotics. In forties to sixties, the term “antibiotic” was clearly different from the term “chemotherapeutic drug”. Chemotherapeutic drugs were man-made substances used to cure the diseases.

“All antibiotics are chemotherapeutic agents, but not all chemotherapeutic agents are antibiotics”

    The word antibiotic denotes:

“A chemical substance derived from a microorganism or produced by chemical synthesis that is able to kill or inhibit microorganisms and cure infections.”

Originally, earliest records say that antibiotics were derived from fungal sources. These can be referred to as “natural” antibiotics. But these Natural antibiotics are more toxic than synthetic antibiotics.

Examples of the natural antibiotics are:

  • Benzyl penicillin
  • Gentamicin

SOURCES OF ANTIBIOTICS:

  • Bacteria (most prolific source is the Streptomycete group)

For example Streptomycin, Tetracycline, Chloramphenicol and Kanamycin etc.

  • Moulds (filamentous fungi) 

For example Penicillins and Cephalosporins

  • Synthetic  antibiotics

For example Chloramphenicol

  • Semi-synthetic

Part of molecule is produced by a microorganism and part of it is modified/ altered chemically to chemically improve it.

E.g. many types of Penicillin - Ampicillin, Methicillin, Carbenicillin, Cloxacillin

CLASSIFICATION:

There are several classification schemes for antibiotics:

  • Based on bacterial spectrum (broad versus narrow)
  • Route of administration (Injectable versus oral versus topical)
  • Type of activity (bactericidal vs. bacteriostatic)
  • Chemical structure.

The most important method of classification is based upon chemical structure. Antibiotics of a particular structural class generally show similar patterns of effectiveness, toxicity, and allergic potential.

The classification according to their structure:

1.   Amino glycosides (Amikacin, Gentamicin, Streptomycin etc.)

     They have very strong and rapid bactericidal effect on bacteria. Amino glycosides are not effective against anaerobes. They act upon several sites of bacterial cell (outer membrane, Ribosomes). Amino glycosides are preferably used in combination with other antibiotics.

  • Streptomycin is an old drug used in the treatment of tuberculosis.
  • Gentamicin is a standard and most widely used amino glycoside.
  • Amikacin and Isepamicin- These antibiotics resist various bacterial destructive enzymes.

2.   Glycopeptides (Vancomycin and Fusfomycin)

They are bactericidal drugs inhibiting bacterial cell wall synthesis in a step prior to beta lactam action. They interfere with RNA synthesis or injure the protoplast. They have large molecular size and hence are not able to penetrate the cell wall and are not absorbed from the gastrointestinal tract. The drugs are excreted almost exclusively by glomerular filtration.

  • Vancomycin

Used for Staph or Strep infections RESISTANT to Methicillin.

Vancomycin potentiates the nephrotoxicity of amino glycosides.

  • Fusfomycin

Inhibits cell wall synthesis

Treatment of uncomplicated UTI only in females

3.   β-lactum:

They are bactericidal drugs. The bacterial enzymes that are affected by beta-lactam are called penicillin binding proteins. They inhibit cell wall synthesis.

  • Penicillins-the usage is against the following:Carbapenems(Imipenem)
    • Gram +ve infections
    • Treponema (Syphilis)
    • Pseudomonas (Penicillin IV + Amino glycosides)
  • Cephalosporins (1st - 4th generation)

4.   Fluoroquinolones (Nalidixic acid):

They are synthetic antibacterial agents, and not derived from bacteria. They are chemically unrelated to the penicillin or the cephalosporin. They get so well absorbed that in general they are as effective by the oral route as by intravenous infusion.

5.   Oxazolidinones (Linezolid)

They bind to 50S and prevent formation of initiation complex and prevent the cell replication. They are used in people who are allergic to Vancomycin. 

6.   Macrolides(Erythromycin)

They are static antibiotics reversibly inhibit protein synthesis on ribosomal level. They are derived from Streptomyces bacteria. Erythromycin, the prototype of this class is used similar to penicillin. After the introduction of more modern members into this class of antibiotics they became very popular because of low frequency of side effects and comfortable usage.

  • Lincosamides (Clindamycin): it is  effective against
    • gram +ve organisms
    • anaerobes (B.fragilis)

7.   Miscellaneous (Metronidazole, Tetracyclin)

  • Tetracyclin: They are derived from a species of Streptomyces bacteria. They are bacteriostatic and used against a large variety of microorganisms, including Rickettsia and amebic parasites.

WHAT IS A PERFECT ANTIBIOTIC?

 A perfect antibiotic should have following features:

  • Non-toxic
  • Non-allergenic
  • Selective target
  • Broad spectrum of activity
  • No development of resistance to it by bacteria
  • Stable
  • Cheap
  • Long shelf life
  • High therapeutic index
  • Variable excretion rate from body (high rate for acute infections and UTIs, low rate for chronic infections)

HOW DO THE ANTIBIOTICS WORK?

Antibiotics act by inhibiting crucial life sustaining processes in the cell/ organism. They work by inhibiting synthesis of cell wall materials like the synthesis of DNA, RNA, Ribosomes and proteins etc. They can be both: bactericidal or bacteriostatic i.e. they can either kill the bacteria or inhibit their multiplication.

DOSAGE RECOMMENDED:

Dosage varies with drug, route of administration, pathogen, site of infection, and severity. Renal function, age of patient, and other factors also impact the dosage. Consultation from the doctor is recommended. Most antibiotics start having an effect on an infection within a few hours.  It is important to remember to complete the whole course of the medication. Some antibiotics should not be consumed with certain foods and drinks while some others should not be taken with the food in your stomach hence they should be taken at least an hour before or after the food intake.

SIDE EFFECTS:

All antibiotics cause risk of overgrowth by non-susceptible bacteria. The common side effects are:

  • Feeling and being sick
  • Diarrhea
  • Fungal infections of the mouth, digestive tract and vagina
  • Allergic reactions, especially from penicillin

Some rare side effects are:

  • Abnormal blood clotting 
  • Sensitivity to sun
  • Formation of kidney stones 

PRECAUTIONS:

  • While taking antibiotic do not take any other OTC/herbal medicine without telling your doctor
  • If you are taking metronidazole do not consume alcohol
  • Dairy products should not be consumed if you are taking tetracycline
  • Do not over use the antibiotics
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