Anticoagulants are the cornerstone therapy for the prevention and treatment of thrombosis. These medications help stop your blood from thickening and prevent formation clotting. Anticoagulants are often blood thinners, but they do not thin the blood. They achieve their effect by suppressing the synthesis or function of various clotting factors normally present in the blood. Such medicines are often prescribed to prevent the formation of blood clots in arteries and veins or the progressing clot circulating in the bloodstream. Unnecessary clots can cause health issues that can be life-threatening. Blood clots that travel to the brain can cause a stroke if to the lungs can lead to pulmonary embolism, and if to the heart, cardiac arrest may occur.
What do anticoagulants do?
Anticoagulants work by preventing clots in your blood vessels. They interfere with the proteins in your blood that are involved with the process of coagulation. Different anticoagulants interfere with different proteins to prevent clotting. Your doctor may recommend an anticoagulant if you have certain medical conditions, including abnormal heartbeat, heart disease, problems with blood circulation, and a congenital heart defect. Your doctor may prescribe one of these medicines if you have had heart valve surgery. If you have been asked to take warfarin, you will have regular blood tests called international normalized ratio (INR) tests. These blood test results help your doctor decide if the anticoagulant medicine is at the right level in your body. Your doctor may order other tests if you take different medications.
How are blood clots treated?
Your body has a way of protecting you from bleeding. Most of the time, clots occur for good. There are times when blood clots can cause complications. If you have certain medical conditions such as congenital heart defect or irregular heart rhythm, or if you had certain procedures such as heart valve surgery, your doctor may give a blood thinner. These heart conditions and heart valve replacement surgery increase the chance of developing life-threatening blood clots, ultimately leading to a heart attack and stroke. Blood thinners are usually prescribed to reduce your risk of heart attack and stroke by decreasing the formation of blood clots.
General categories used to prevent blood clots: anticoagulants and anti-platelet medications. Some of these may be unfamiliar, while others are generally household names. These anticoagulants are available online; you can buy anticoagulation medicines online at reasonable prices. They have a different mode of action and are used under different circumstances. One possible side effect common to all is excessive bleeding, so one must use the drugs appropriately. While oral medications are the first-line treatment for blood clots, certain patients may require surgery to prevent the formation of clots.
If you have or are suspected of having a blood clot, you will likely visit a clinician’s place. What you take usually depend on several factors, including your overall health, the probable cause of the clot, its severity and other associated factors.
Anticoagulant medications tend to inhibit one or more clotting factors, a group of blood proteins responsible for blood clotting. The drugs include:
• Warfarin- Warfarin is a type of anticoagulant or a blood thinner. It is used to treat blood clots and prevent new clots from forming in your body. Preventing dangerous blood clots helps to reduce the risk of serious heart complications such as a stroke and a heart attack. Warfarin makes blood circulation through your veins more easily. Therefore, your blood will be less likely to make a life-threatening blood clot. Warfarin is sold under various brand names, including Warf, or warfarin, to treat people who have a history of clots, such as a blood clot in the leg or a blood clot in the veins.
This group of drugs is used to reduce platelets' stickiness (tiny blood cells that form the nucleus of a clot). By hindering the ability of platelets to clump together, anti-platelet medications inhibit blood clotting. These drugs are extremely effective at preventing abnormal blood clots from forming in arteries and are much less effective in preventing thrombosis in veins (when clots block the blood vessels).
• Clopidogrel- It is an anti-platelet medicine that prevents sticking together and forming a dangerous blood clot. Taking this anti-platelet drug helps prevent clots if you are at increased risk of developing them. Your risk is even greater if you have or have had a heart attack, unstable angina, stroke, peripheral arterial disease, or an operation on your heart/blood vessels, such as coronary stent insertion. The usual dose for the drug is 75 mg once a day. Your doctor may prescribe clopidogrel with or instead of low-dose aspirin. The main side effect of the drug is bleeding. Other side effects include bleeding gums, nosebleeds, bruising or heavy periods.
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How to take Anticoagulants?
Your doctor will tell you how much of your anticoagulant drug to take, when to take and when to take it. In general, most patients are advised to take their oral medicine once or twice daily with water or food. The duration of treatment depends on what has been prescribed. In many cases, treatment continues for the rest of life. Talk to your doctor if you have any doubt about taking medicine or are concerned that you missed a dose or have consumed too much.
What are the Side effects and risks of using Anticoagulants
There are side effects associated with anticoagulant medicines, and some can be serious. Speak to your doctor if you notice any of the following symptoms while taking any anticoagulant medication:
• Red or pink colour urine
• purple toes
• increased bruising
• Stools that appear bloody or look like coffee grounds
• Pain, change in temperature, or blackish skin of your fingers, hands, toes, or feet
Because of the side effects of anticoagulant medications, certain people have an increased risk of complications when using them. Some people should avoid the use of these medicines completely. Speak to your doctor if you have bleeding problems, high blood pressure, congestive heart failure, balance problems, diabetes, kidney, or liver problems. Warfarin, a commonly prescribed blood thinner, may make you more likely to develop complications associated with these conditions. If you are pregnant or breastfeeding, avoid the use of warfarin. Taking a blood thinner during pregnancy can increase the risk of fetal death and harm your baby. Certain other medications and dietary supplements can further increase your risk of bleeding, so tell your doctor about all the medications you take, including what you get over the counter.
While you take any of this anticoagulant medication, follow these steps to help your health and safe:
• Tell your doctor that you are taking an anticoagulant before wishing to take another medicine.
• Avoid sports and other activities that make you more prone to injuries. It may be hard for your body to stop bleeding.
• Speak to your doctor if you and your doctor plans to have surgery or certain dental procedures. This helps to avoid the risk of bleeding that is difficult to stop. Your doctor may advise you to stop taking the anticoagulant medication for a period before and after the procedure.
Speak to your doctor
The risks and side effects associated with anticoagulants can be serious. When taking these medicines, follow the instructions given by your doctor and inform him if you miss a dose.
Patients may need to stop oral anticoagulants, including warfarin, before a coronary angiogram. This usually depends on the type of procedure planned and the patient's specific medical history. A Health care professional will provide the patient with a stop-taking date.
Anti-inhibitor coagulant complex is a medicine used to treat haemophilia in patients with factor VIII inhibitor antibodies. Haemophilia is a blood disorder characterized by prolonged coagulation time. During this condition, blood fails to clot, and abnormal bleeding occurs. Anti-inhibitor complex medicine controls and prevents bleeding episodes. It is also used as routine prophylaxis to prevent or reduce the frequency of bleeding.
Anticoagulants are drugs known as blood thinners that interfere with the body's natural blood-clotting mechanism. They are necessary if a patient is dealing with deep vein thrombosis, a blood clot in a vital organ such as the liver, heart, or brain or if the patient has a condition predisposed to blood clot formation such as atrial fibrillation.
Various anticoagulant solutions allow blood to be stored for an extended period without clotting or major changes in most metabolic and therapeutic qualities. Citrate-phosphate-dextrose (CPD) is a traditional anticoagulant/preservative that allows 21 days of RBC or whole blood storage.
Studies show ginger has anticoagulant activity; the natural herb inhibits the clot formation and significantly prolongs prothrombin time. Here prolonged prothrombin time means the blood takes too long to form a clot.
The most serious complication associated with using anticoagulants is bleeding due to excess anticoagulation. An intestinal hematoma is a rare complication of anticoagulant therapy that results from bleeding inside the muscle layer of the abdominal wall.
Intracerebral haemorrhage (bleeding in the brain tissue) is a life-threatening complication of oral anticoagulants, including warfarin. Anticoagulant treatment is associated with an increased risk of bleeding complications. If a patient takes an anticoagulant drug, the risk of disability and death is substantially higher. Therefore, it is recommended to consult a doctor before using an anticoagulant drug.
Anticoagulants save lives. But they also cause side effects, like bleeding. Therefore, people taking anticoagulants should inform their health care experts of any bleeding or unusual bruising. Sometimes, it may be life-threatening and requires immediate medical attention. Some cases are not life-threatening, but bleeding can still be a nuisance.
There are different types of blood thinner medications, including
Blood thinners are the drugs that help blood flow smoothly through your veins and arteries. They also prevent the formation of blood clots or keep them from getting bigger. They are often prescribed to treat some types of heart disease and other conditions that could increase your risk of getting dangerous blood clots.