Available Dosages
| SKU: | 286 |
|---|---|
| Generic For: | Cyclosporin |
| Active Ingredient: | Cyclosporine |
| Manufacturer: | Biocin Ltd, India |
Buy Cyclophil Me 25mg (Cyclosporine) Online
Cyclophil Me 25 mg is used after organ or bone marrow transplantations to help prevent organ rejection or treat autoimmune conditions such as severe rheumatoid, psoriasis, and nephrotic syndrome. It belongs to the class of medications known as immunosuppressants, which suppress or reduce the body’s immune response.
In general, your body’s immune system normally works to protect you against infections and other foreign material. When you undergo a transplant, your immune system fails to recognize the new organ and will try to reject it. Cyclophil reduces this response so that your body can accept the new organ. Cyclosporine does not completely suppress the immune system, so your body will have some infection-fighting ability. It may be given alone but is often given with other medications which also work by suppressing your immune system. Together these help prolongs the life of an organ transplant or suppresses certain immune functions to treat psoriasis, rheumatoid arthritis, or nephrotic syndrome.
Do not use Cyclophil Me if you have ever had an unusual allergic reaction to Cyclosporin or any other medicine ingredients. For the treatment of rheumatoid arthritis, psoriasis, and nephrotic syndrome, if you have any of the following conditions:
- Uncontrolled blood pressure
- Abnormal kidney function
- Uncontrolled infection
- Any cancer
- Inherited or acquired immune deficiency
Avoid using Cyclophil Me with bosentan.
Medicines that are used to suppress the immune system may influence your body’s ability to fight against infection and may increase the risk of developing cancers associated with the skin or lymphoid system. Therefore, limiting exposure to sunlight and ultraviolet rays is important by wearing appropriate protective clothing and frequently applying sunscreen with a high protection factor.
The most common side effects of Cyclophil Me are:
— High blood pressure
— Headache
— Kidney or liver problems
— Acne or oily skin
— Increased growth of fine hairs in the body
— Loss of appetite, vomiting, nausea, diarrhoea
— Weakness, anxiety
— Decreased ability to fight infection
— Stomach ulcer
— Hot flushes
— Slight trembling of the hands
— Muscle or joint pain or cramping
— Low levels of white blood cells.
Be sure to tell your doctor if you notice any unwanted effects associated with the use of Cyclosporine.
Always take Cyclosporine exactly as your doctor prescribed you. You should check with your doctor if you have any doubts about the usage of the medicine. Do not make any changes in your dosing regimen by yourself. Space your dose as evenly as you can throughout the day. For instance, if you take medicine twice daily, leave about twelve hours between doses. Try to take the doses at the same each day as this helps to keep a constant amount of drugs in your body. Never take medicine with grapefruit juice. Swallow the capsule whole with a glass full of water. Consult your doctor for a dosing regimen. Blood tests are one way your doctor tells you how much Cyclophil Me you need. Your doctor may change your dosing regimen based on these tests and your response to this medicine.
What is Cyclophil Me 50mg used for?
Cyclophil Me 50mg contains cyclosporine 50mg per capsule, an immunosuppressant used to prevent organ rejection after transplantation and to treat severe autoimmune diseases including psoriasis, rheumatoid arthritis, and nephrotic syndrome. The 50mg capsule allows flexible dosing for patients on lower maintenance doses or for dose fine-tuning. Cyclosporine suppresses T-lymphocyte activation, preventing immune-mediated attacks on transplanted organs or healthy tissue. It is prescribed across the USA, UK, and Australia as part of multi-drug immunosuppressive protocols.
How is Cyclophil Me 50mg different from Cyclophil Me 100mg?
Cyclophil Me 50mg and 100mg contain the same active ingredient — cyclosporine microemulsion — but differ in dose strength per capsule. The 50mg capsule offers greater dose flexibility, particularly useful for paediatric dosing, lower maintenance doses in stable transplant patients, or precise dose adjustments in autoimmune conditions. Patients sometimes take a combination of 50mg and 100mg capsules to achieve their prescribed total daily dose. The pharmacokinetics, formulation type, and clinical considerations are identical between both strengths — only the quantity of drug per capsule differs.
What dose of Cyclophil Me 50mg is typical for psoriasis treatment?
For plaque psoriasis, cyclosporine (Cyclophil Me 50mg) is typically started at 2.5 mg/kg/day in two divided doses. If the response is inadequate after 4 weeks, the dose may be increased to a maximum of 5 mg/kg/day. Treatment courses are generally limited to 12 weeks for intermittent therapy or up to 2 years for continuous therapy, with regular monitoring of renal function, blood pressure, and cyclosporine levels. The 50mg capsule is particularly useful for lower starting doses in psoriasis patients where transplant-level dosing is not required.
Should Cyclophil Me 50mg be taken at the same time each day?
Yes. Cyclophil Me 50mg should be taken at the same times each day — typically split into two equal doses, 12 hours apart. Consistent timing maintains stable blood trough levels, which is critical for narrow therapeutic index drugs like cyclosporine. Missing a dose and then doubling up can cause toxic peaks. If a dose is missed by less than 4 hours, take it as soon as possible. If more than 4 hours have passed, skip and resume the next scheduled dose. Grapefruit products must be avoided throughout therapy due to CYP3A4 inhibition.
Can Cyclophil Me 50mg affect kidney function?
Nephrotoxicity is the most clinically significant adverse effect of cyclosporine, including Cyclophil Me 50mg. Cyclosporine causes afferent arteriole vasoconstriction in the kidney, reducing glomerular filtration rate. Serum creatinine levels typically rise by 20–30% during therapy — a rise above 30% from baseline warrants dose reduction. Long-term cyclosporine use can lead to chronic cyclosporine-induced nephropathy with structural kidney changes. Regular monitoring of serum creatinine, urea, and potassium every 2–4 weeks during initiation and at least every 3 months during stable maintenance is mandatory.
What should I avoid while taking Cyclophil Me 50mg?
While taking Cyclophil Me 50mg, avoid grapefruit and grapefruit juice (inhibits cyclosporine metabolism), NSAIDs and aminoglycoside antibiotics (increase nephrotoxicity), potassium-rich foods or supplements in excess (hyperkalaemia risk), live vaccines, and St John's Wort (reduces cyclosporine levels). Excessive sun exposure should also be limited, as cyclosporine-induced immunosuppression significantly increases the risk of skin cancers. Regular sunscreen use and annual dermatological checks are advised for long-term cyclosporine users. Always disclose all supplements and OTC medications to your prescribing physician.
Is Cyclophil Me 50mg suitable for children?
Cyclosporine (Cyclophil Me 50mg) is used in paediatric transplant patients and in children with nephrotic syndrome, typically under specialist supervision at tertiary centres. Dosing in children is weight-based (mg/kg/day), and the 50mg capsule's smaller increment facilitates more accurate paediatric dosing. Children often have higher cyclosporine clearance rates than adults, requiring proportionally higher mg/kg doses to achieve target trough levels. Frequent blood level monitoring is especially important in paediatric patients. The decision to use cyclosporine in children should always be made by a specialist with paediatric transplant or nephrology experience.
How does Cyclophil Me 50mg compare to tacrolimus for transplant patients?
Cyclosporine (Cyclophil Me 50mg) and tacrolimus are both calcineurin inhibitors, but tacrolimus has largely replaced cyclosporine as first-line therapy in kidney and liver transplantation due to lower acute rejection rates. However, cyclosporine has a distinct side effect profile — less diabetes-inducing than tacrolimus but causing more hypertension, hirsutism, and gingival hyperplasia. Some centres still prefer cyclosporine in specific patient populations, including those at high risk of post-transplant diabetes. The choice between the two is made by the transplant physician based on individual patient risk factors.
Can I order Cyclophil Me 50mg from AllDayChemist for long-term supply?
Yes, Cyclophil Me 50mg is available at AllDayChemist for long-term supply, which is especially important for transplant patients who require uninterrupted immunosuppression. AllDayChemist has been serving patients globally since 2002, sourcing authentic cyclosporine directly from licensed manufacturers. Competitive pricing, discreet packaging, and worldwide tracked shipping make AllDayChemist a practical option for patients in the USA, UK, and Australia managing ongoing transplant medication costs. Consult your transplant physician before making any changes to your cyclosporine supply source.
Is AllDayChemist a reliable source for Cyclophil Me 50mg?
AllDayChemist is a licensed pharmacy operating since 2002, serving most of the countries with authentic, manufacturer-sourced medications. For critical narrow therapeutic index medications like cyclosporine, source reliability is paramount — counterfeit or substandard cyclosporine can directly lead to transplant rejection. AllDayChemist supplies Cyclophil Me 50mg from verified pharmaceutical manufacturers, ensuring consistent product quality. Free worldwide shipping and discreet packaging are additional benefits. Transplant patients should inform their transplant team when sourcing medications internationally to ensure consistent monitoring protocols.
What are the side effects of Cyclophil Me 50mg?
Common effects include kidney-related problems, increased blood pressure, hand tremors, unusual hair growth, swollen or overgrown gums, higher cholesterol levels, elevated uric acid, and elevated blood potassium levels. Some people may also experience headaches, tingling, or numbness in the hands and feet. Regular medical check-ups and blood tests are important while using this medicine to monitor these effects and maintain safe treatment. Gastrointestinal side effects include nausea, vomiting, and diarrhoea. The immunosuppressive effect increases susceptibility to bacterial, viral (especially CMV and EBV), and fungal infections, and raises the long-term risk of lymphoma and non-melanoma skin cancers. All side effects should be reported to the prescribing physician.
What signs of toxicity should I watch for with Cyclophil Me 50mg?
Key warning signs of cyclosporine toxicity from Cyclophil Me 50mg include a significant rise in serum creatinine (>30% above baseline), persistent elevated blood pressure despite antihypertensive treatment, unexplained neurological symptoms (seizures, confusion, visual disturbances — signs of posterior reversible encephalopathy syndrome/PRES), muscle weakness, severe infections, or jaundice suggesting hepatotoxicity. Any of these symptoms require urgent medical review and blood level testing. Never adjust or stop cyclosporine without medical supervision, as abrupt cessation in transplant patients can trigger acute rejection epiSodiumes.
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign Up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Forgot Password ?