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Foseal 400 mg contains the active ingredient Sevelamer hydrochloride, polymer phosphate binder discovered for oral administration. It binds phosphate from food in the digestive tract and therefore causes a significant reduction in the serum phosphate levels in the bloodstream. Your doctor may prescribe Foseal to control phosphate levels in the bloodstream of patients with chronic kidney disease on dialysis treatment. Adults who suffer kidney failure or are undergoing hemodialysis or peritoneal dialysis cannot control serum phosphate levels in their blood. The amount of phosphate then rises, and clinicians termed this condition hyperphosphatemia. Excessive amounts of phosphate can cause hard deposition in the body called calcification. These deposits can stiffen your blood vessels and make it difficult for blood to flow around the body. The symptoms of an increase’s serum phosphate include itchy red eyes, bone pain and fractures. Sevelamer can be used in combination with other drugs, including vitamin D or calcium supplements, to control the development of renal bone disease.
Do not take Foseal 400 mg if you lower phosphate levels in your blood, have a bowel obstruction, or are allergic to Sevelamer. Speak to your doctor while taking a Sevelamer formulation if you experience severe stomachache, abdominal pain, intestine disorders, or blood in the stools. These symptoms occur due to serious inflammatory bowel disease caused by the sevelamer crystal deposit in your bowel. Your doctor will decide whether you need to continue the medicine or not. Talk to your doctor before taking Foseal tablets if you have swallowing problems, issues with bowel movement, the feeling of fullness, prolonged diarrhea, have undergone major surgery, or are not on dialysis. For patients on peritoneal dialysis, you may develop an infection of your abdominal fluid associated with your peritoneal dialysis. You can reduce the risk by carefully adhering to techniques during bag changes. You should inform your doctor right away if you develop new symptoms of abdominal distress- abdominal swelling, tenderness, rigidity, nausea, vomiting, fever, chills, or constipation. Your doctor may monitor you more carefully if you have problems with low vitamin A, D, E, K, and folic acid levels.
There are certain medicines that you should not take at the same time as Sevelamer.
Since constipation is a symptom in rare cases of blockages in your intestine, it is necessary to inform your doctor of this symptom or during the treatment. Common side effects of the medicine include nausea, vomiting, indigestion, abdominal pain, constipation, flatulence, and diarrhea. Rarely a hypersensitivity reaction may occur. Symptoms of a severe allergic reaction include hives, rash, swelling, and breathing problems. If you get any of these side effects, talk to your doctor.
Always take Foseal 400 mg exactly as your doctor has told you. You should check with your doctor if you are not sure about the correct usage of this medicine. Usually, the dose is based on the serum phosphate level of a patient. The recommended dose for adults and the elderly over 65 is two to four tablets with each meal thrice daily. During the initial days of the treatment, your doctor will monitor you for phosphate levels in your bloodstream every 3 to 4 weeks and may adjust the dose of Foseal when required. Swallow the tablet whole with a drink without chewing or crushing it. Patients receiving Sevelamer formulation should stick to the prescribed diet and liquid intake. In case of a possible overdose, you should contact your doctor straight away.