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Pangraf 0.5mg


US$ 0.93

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More Information
SKU 1044
Generic For Prograf
Generic Name Tacrolimus
Manufacturer Panacea Biotech, India
Pack Size Qty Price Per Pill or Unit Price Cart
30 Tablet/s US$ 1.08 US$ 32.50
60 Tablet/s US$ 1.00 US$ 60.008%US$ 65.00
90 Tablet/s US$ 0.93 US$ 84.0014%US$ 97.50
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Pangraf 0.5 mg is an immunosuppressive drug that suppresses your body’s immune power. The immune system helps your body guard against invading foreign bodies, which can cause infections and illnesses, thereby preventing common or dangerous diseases. The same immune system can be a disadvantage during an organ transplant as it will treat the organ implanted as a foreign body. Your body will reject it (organ) completely from integrating.

Pangraf contains Tacrolimus as the main active salt, which is used along with other medications to stop your body from rejecting a transplanted heart, liver, or kidney. This medication may also be given for conditions other than that mentioned here.

Some of the drugs which can interact with Tacrolimus are St John’s Wort; antacids like Maalox, Rolaids, Rulox, or others; antibiotics like levofloxacin, rifampin or erythromycin; antidepressants like desipramine or nefazodone; antifungals like caspofungin, posaconazole, voriconazole or others; barbiturate like Phenobarbital; contraceptive pills or hormone replacement drugs; heart or blood pressure drugs like amiodarone, amlodipine, diltiazem; nifedipine, quinidine, or others; HIV/AIDS drugs like atazanavir, ritonavir or others; hepatitis C medications like telaprevir or boceprevir; seizure medications, steroid medications, or stomach acid reducers like lansoprazole, cimetidine or others. This list is a partial list of drugs that can interact with Tacrolimus and other drugs that can interact with it. Share your medical history and list all current medications you may be taking.

Don’t take Pangraf medication if you are allergic to Tacrolimus, hydrogenated castor oil, or if you have taken cyclosporine in the last 24 hours. Tacrolimus lowers blood cells that primary bodyguard against infections. It can also cause your body to generate a large quantity of certain white blood cells. All of these can result in serious and sometimes fatal outcomes like cancer. This serious brain infection can cause disability or death, or your body catching a virus that can lead to the failure of a transplanted kidney. Tacrolimus usage over time may also increase the likelihood of developing skin cancer. Ask your doctor about all the risks associated with this medication.

Tacrolimus is categorized as an FDA pregnancy category C drug. The effects of this drug on an unborn baby are not known. Let your doctor know if you are pregnant or planning to become pregnant. Tacrolimus can pass into breast milk and harm your baby. It is not recommended if you are nursing a baby. Take Tacrolimus strictly after medical advice if you have kidney or liver disease; heart disease; high blood pressure; or high cholesterol; if you also take sirolimus; or if you take other immunosuppressive drugs such as anticancer or steroids.

Things and activities to avoid while taking Pangraf

Avoid grapefruit and related products while taking Tacrolimus, as grapefruit consumption and Tacrolimus can cause dangerous effects. Don’t go near sick people; inform your doctor immediately if you develop an infection.

Tacrolimus may lead to some serious side effects like skin hives, breathing difficulty, swelling in different places, fever, chills, body aches, flu symptoms, change in mental state, vision problems, speech and walking problems, pale or yellow colored skin, dark urine, weakness or confusion, concentration difficulty, lightheadedness, shortness of breath, increase heart rate, decrease urination, cough with mucus or blood, excessive sweating, tremors, increased potassium in the blood (muscle weakness, tingly feeling), low magnesium (slow reflexes, jerky muscle movements), high blood pressure, or high sugar.


Some less serious side effects of Tacrolimus are stomach pain, constipation, nausea, headache, insomnia, or limb swelling. All the side effects thus listed are non-exhaustive, and there may be other side effects. Contact your doctor for side effects advice.

You must take Pangraf medication exactly as prescribed by your doctor. Don’t alter the prescribed dosage unless directed by your doctor, who may occasionally change your dosage.

You may receive a Tacrolimus injection initially after your transplant. Tacrolimus injection is given until you are prepared to take the oral pill form. The tacrolimus capsule is usually taken every 12 hours or twice each day. Instil a habit of taking medicine at the same point of time each day.

Always store Tacrolimus medication in a cool and dry place. Ensure that children or pets don’t have access to it or any other medications.

The dosing of Tacrolimus depends on various factors, and your doctor may fix an appropriate dose for you after a thorough examination and tests. The seriousness of the condition, age, sex and a host of other factors are considered when deciding the dosage of Tacrolimus. Strictly stick to the prescribed dosage for the best results.

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