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Pramipexole: An Effective Treatment for Parkinson’s Disease

Pramipexole is a dopamine agonist belonging to the class of non-ergoline medicines. Most commonly, Pramipexole DiHydrochloride is used for the treatment of Parkinson’s disease and Restless Legs Syndrome at early stages. In certain cases, Pramipexole di-hcl can also be used to treat cluster headache or to counteract sexual dysfunction problems encountered by patients using an SSRI antidepressant. It has also been tested to treat fibromyalgia and clinical depression in some patients. In some cases, it is used as a substitute for Carbidopa Levodopa for the treatment of Parkinson’s disease.

How Pramipexole DiHydrochloride works

Being a dopamine agonist, the drug works by restoring dopamine balance in the patient’s brain, thereby improving your ability to move and decreasing stiffness, unsteadiness, slowed movement and shakiness due to the disease. It also decreases the number of attacks when you are not able to move because of the disease, termed as on-off syndrome. By relieving the unpleasant and uncomfortable feelings in legs during nights, Pramipexole treats Restless Legs Syndrome and improves sleep.

How the drug is given

Pramipexole Di-Hcl is available in the form of oral tablets and as extended release oral tablets. You can take the tablets with or without meals, as prescribed by your doctor. Taking them with food can reduce nausea. In order to reduce side effects, your doctor will start the treatment with a lower dose and then gradually increase it. In order to keep the drug level constant in your body, try to take it at the same time each day. If your doctor thinks that it is time to stop the medication, he or she will decide to gradually decrease the dosage, instead of stopping it all at once. Therefore, consult your doctor before reducing or stopping the medication, as severe reactions may take place. If you are using the extended release tablet form of Pramipexole, you will have to swallow the tablet whole, without chewing, crushing or breaking it.

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