Available Dosages
| SKU: | 553 |
|---|---|
| Generic For: | Isordil |
| Active Ingredient: | Isosorbide Dinitrate |
| Manufacturer: | Abbott Healthcare, India |
Buy Sorbitrate 10mg (Isosorbide Dinitrate) Online
Sorbitrate 10 mg prevents chest pain (angina) in patients with a certain heart conditions, including coronary artery disease. It contains the active ingredient Isosorbide dinitrate, which belongs to a class of drugs known as nitrates that causes the widening of blood vessels so that blood can flow more easily to the heart. This medicine will not relieve chest pain once it occurs. This medicine should not be used before physical activities to prevent chest pain. Other medicines may be required in these conditions. Speak to the doctor for more information.
Before taking Sorbitrate 10 mg, tell your doctor if you are allergic to it or similar drugs or have any other allergies. This medicine may cause inactive ingredients, which can cause allergic reactions or other problems. Talk to your doctor for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, talk to your doctor if you have had recent head surgery.
Before you take Isosorbide dinitrate, tell your doctor of your medical history, especially of anemia, dehydration, low blood pressure, and other heart problems.
Sorbitrate may make you dizzy. Alcohol or marijuana may make you dizzier. Avoid driving, using machinery, or doing things that need alertness until you can do it safely.
Before having surgery, let your doctor know that you are using this medicine. Older adults may be more sensitive to the side effects of this medicine, especially dizziness and lightheadedness, which could increase the risks of falls.
Headache, nausea, dizziness, lightheadedness, and flushing may occur. If any of these side effects worsen or persist, tell your doctor immediately. Headache is often a sign that this medicine is working. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as aspirin or acetaminophen). Talk to your doctor immediately if the headaches continue to become severe. To reduce lightheadedness, get up slowly from a sitting or a lying position.
A very serious allergic reaction to Sorbitrate is rare. However, seek immediate medical help if you notice any of the following symptoms of a serious allergic reaction:
— Itching
— Rash
— Swelling of the face/throat/tongue
— Severe dizziness
— Trouble breathing
This is not the complete risk of side effects. Contact your doctor if you notice other side effects not listed in this information guide.
Take Sorbitrate orally, usually 2 to 3 times daily or as directed by your doctor. It is important to take this medicine at the same time each day. Do not change the dosing regimen unless directed by your doctor. Use this medicine regularly to get the most benefit from the medication. Do not discontinue treatment without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. The dose may need to be gradually increased. Sometimes, when Sorbitrate is used for a long time, it may not work well and may require different dosing. Tell your doctor if this medicine stops working well or you have worsening chest pain.
What is Sorbitrate 10mg used for?
Sorbitrate 10mg contains Isosorbide Dinitrate (ISDN) 10mg, an organic nitrate used for both the acute relief and prevention of angina pectoris. Sublingual Isosorbide Dinitrate provides rapid relief of acute angina attacks, while oral tablets are used for prophylaxis. Sorbitrate is also used in heart failure as a vaSodiumilator (often combined with hydralazine as the Bidil combination).
How does Isosorbide Dinitrate in Sorbitrate 10mg work?
ISDN is converted in the body to two active metabolites — Isosorbide-2-mononitrate and Isosorbide-5-mononitrate (the more active form). These release nitric oxide in vascular smooth muscle, causing venodilation and arterial dilation. Venodilation reduces cardiac preload; arterial dilation reduces afterload. The net effect is decreased myocardial oxygen demand, preventing and relieving angina.
How should Sorbitrate 10mg be taken for angina prevention?
For prophylaxis, Sorbitrate 10mg oral tablets are taken two to three times daily on an eccentric schedule to avoid tolerance. A typical schedule is 7am, 12pm, and 5pm — ensuring a nitrate-free period of at least ten to twelve hours overnight. The dose can range from 5mg to 40mg per dose depending on individual response. Follow your cardiologist's prescribed schedule precisely.
Can Sorbitrate 10mg be used for acute angina attacks?
Sorbitrate 10mg oral tablets take 20–30 minutes to work and are therefore too slow for acute angina relief. For acute attacks, sublingual ISDN (held under the tongue) or sublingual/spray glyceryl trinitrate are appropriate. Oral Sorbitrate 10mg is for scheduled prophylaxis only. Always carry a short-acting sublingual nitrate for breakthrough epiSodiumes alongside your regular Sorbitrate regimen.
Is Sorbitrate 10mg suitable for patients with heart failure?
Yes. ISDN combined with hydralazine (the Bidil combination) is an evidence-based therapy for heart failure with reduced ejection fraction, particularly in African American patients who may not tolerate ACE inhibitors. The ISDN component reduces preload and afterload on the failing heart. Sorbitrate 10mg can be part of this combination. The V-HeFT and A-HeFT trials confirmed the mortality benefit of this regimen.
What happens if I develop tolerance to Sorbitrate 10mg?
Nitrate tolerance develops with continuous ISDN exposure and results in loss of antianginal efficacy. The eccentric dosing schedule (e.g., 7am, 12pm, 5pm) with a ten to twelve-hour nitrate-free interval prevents tolerance by allowing the vascular system to resensitise overnight. If you notice your Sorbitrate is becoming less effective, inform your cardiologist — tolerance or disease progression may be responsible.
How does Sorbitrate 10mg compare to sublingual glyceryl trinitrate for angina?
Sorbitrate 10mg oral tablet is not interchangeable with sublingual GTN. GTN spray or sublingual tablet acts within one to three minutes to abort an acute angina attack. Sorbitrate 10mg oral takes 20–30 minutes for onset and is used for scheduled prevention, not acute relief. Both drugs work through nitric oxide-mediated vaSodiumilation but have very different onset times and indications.
Is Sorbitrate 10mg an affordable option for angina management?
Yes. Sorbitrate 10mg is a cost-effective generic ISDN tablet available at AllDayChemist at significantly lower prices than branded nitrate therapy in the USA or UK. For patients requiring regular daily antianginal medication, AllDayChemist's competitive pricing and international shipping make ongoing therapy financially accessible. Operating since 2002 with manufacturer-direct sourcing ensures quality.
Can I order Sorbitrate 10mg from AllDayChemist?
Yes. Sorbitrate 10mg is available at AllDayChemist with worldwide shipping to the USA, UK, Australia, and 200+ countries. Operating since 2002, AllDayChemist sources medicines directly from manufacturers. Orders ship in discreet, plain packaging with tracking. Free shipping is available on qualifying orders. Visit AllDayChemist.com.
What makes AllDayChemist a trusted source for cardiac medications like Sorbitrate?
AllDayChemist has built a 20+ year track record of supplying authentic cardiac medications to patients in 200+ countries since 2002. All medications, including Sorbitrate 10mg, are sourced directly from licensed manufacturers — ensuring quality and authenticity. Competitive pricing, discreet worldwide delivery, and free shipping on qualifying orders make AllDayChemist a comprehensive solution for ongoing cardiac therapy.
What side effects does Sorbitrate 10mg cause?
Headache is the most common side effect of Sorbitrate 10mg, often occurring shortly after each dose. This is a direct result of cerebral venous dilation. Other effects include flushing, dizziness, palpitations, and orthostatic hypotension. Headache typically improves with continued use as partial tolerance develops to this effect while antianginal tolerance is prevented by eccentric dosing. Paracetamol can help with headache management.
What precautions should I take with Sorbitrate 10mg?
Never combine with PDE-5 inhibitors — severe, potentially fatal hypotension results. Rise slowly from seated positions. Keep sublingual GTN for acute attacks. Do not stop abruptly — rebound angina can occur. Avoid alcohol as it potentiates hypotensive effects. Inform all medical providers about Sorbitrate use. Do not confuse oral Sorbitrate with sublingual preparations — the routes and dosing are different and not interchangeable.
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