Available Dosages
| SKU: | 11 |
|---|---|
| Generic For: | Zovirax |
| Active Ingredient: | Acyclovir |
| Manufacturer: | Cipla, India |
Buy Acivir Dispersible Tablets 400mg (Acyclovir) for Herpes & Chickenpox
Acivir 400mg DT is a prescription oral antiviral tablet containing 400mg of Acyclovir in a dispersible tablet (DT) formulation, used for the treatment and suppression of herpes simplex virus (HSV) infections and varicella-zoster virus (VZV) infections. Acivir 400mg DT is one of the most prescribed Acyclovir formulations, offering the convenience of a dispersible tablet that can be dissolved in water for patients who have difficulty swallowing, while delivering the same antiviral efficacy as standard film-coated tablets. It is used across a range of herpetic infections, including genital herpes, oral herpes, herpes zoster (shingles), and chickenpox.
What is Acivir 400mg DT?
Acivir 400mg DT is an oral dispersible tablet containing Acyclovir 400mg, a synthetic purine nucleoside analogue with selective antiviral activity against herpes viruses. The dispersible formulation dissolves readily in water, making it suitable for adults who prefer liquid administration, for patients with dysphagia, and for precise dosing in patients who need to partially dissolve the tablet. Acyclovir 400mg is the standard dose for genital herpes treatment and suppression, herpes simplex encephalitis prophylaxis following IV treatment, and one of the doses used in the treatment of varicella-zoster infections. The 10-tablet pack provides a complete course for many acute herpes treatment indications.
Manufacturer: Acivir 400mg DT is manufactured by Cipla Ltd, a globally trusted Indian pharmaceutical company with decades of experience in antiviral medicines and a strong reputation for high-quality Acyclovir formulations under the Acivir brand.
Key Ingredients of Acivir 400mg DT and its working mechanism
Acyclovir is a selective antiviral agent that must be phosphorylated to its active triphosphate form to exert its effect. The first, and rate-limiting, phosphorylation step is carried out exclusively by thymidine kinase (TK) produced by herpes simplex and varicella-zoster viruses—not by normal human cells. This viral enzyme selectivity underlies Acyclovir’s exceptional safety profile and specificity. Acyclovir monophosphate is then further phosphorylated by cellular enzymes to Acyclovir triphosphate. The triphosphate form is a potent, selective inhibitor of viral DNA polymerase — with 30 to 50 times greater affinity for the viral enzyme than for human DNA polymerase — and also acts as a chain terminator, halting viral DNA replication by incorporation into the growing viral DNA strand. The result is the inhibition of viral replication specifically within infected cells, without harming uninfected host cells.
Clinical Uses of Acyclovir 400mg
Acyclovir 400mg is indicated for the treatment of initial and recurrent genital herpes (HSV-2) — the standard treatment dose is 400mg three times daily for 5–10 days. For suppressive therapy in patients with frequent recurrences (more than six per year), 400mg twice daily significantly reduces recurrence frequency and viral shedding. It is also used to treat herpes labialis (cold sores/HSV-1) and oral mucositis caused by HSV in immunocompromised patients. In varicella (chickenpox), doses of 400–800mg are used depending on age and severity. For herpes zoster (shingles), higher doses are used. Following IV Acyclovir therapy for herpes simplex encephalitis, oral Acyclovir suppression is continued for several months.
Comparing Acivir 400mg DT and Zovirax: Brand vs Generic Differences
Acivir 400mg DT is a generic equivalent of Zovirax 400mg (ViiV Healthcare/GSK), the original branded Acyclovir product. Both contain Acyclovir 400mg as the active ingredient and are bioequivalent. The dispersible tablet formulation of Acivir offers an additional convenience advantage — the tablet can be dissolved in water for patients who prefer liquid administration. Zovirax commands a substantial price premium, while Acivir from Cipla provides the same antiviral efficacy at considerably lower cost.
Related strengths and products: Acivir 800mg DT is available for conditions requiring higher doses — including herpes zoster and chickenpox in adults — offering the convenience of fewer tablets per dose. Acivir Cream 10gm (Acyclovir 5% topical) is available for the topical treatment of cold sores and superficial herpes simplex skin infections. Acivir Eye Drops and Acivir Eye Ointment (Acyclovir 3%) are available for herpes simplex keratitis under ophthalmic supervision.
Key Benefits of Acivir 400mg DT
Acivir 400mg DT provides a flexible, easy-to-administer dispersible formulation of Acyclovir, the gold-standard antiviral for herpes infections. When initiated promptly at the onset of a herpes episode, it shortens the duration of the attack, reduces symptom severity, and accelerates healing. For patients on suppressive therapy, it dramatically reduces the frequency of recurrences. As a Cipla product, it delivers pharmaceutical-grade Acyclovir quality at a price accessible for both acute and long-term suppressive use.
Usage warnings and precautionary advice for using Acyclovir 400mg
Acivir 400mg DT is generally well tolerated but requires adequate hydration to prevent crystallisation of Acyclovir in the renal tubules (crystal nephropathy), particularly at higher doses. Dose reduction is required in renal impairment; the dose and frequency should be adjusted based on creatinine clearance. Probenecid and cimetidine increase Acyclovir plasma levels by reducing renal clearance. Concurrent use with nephrotoxic agents increases the risk of renal toxicity. Central nervous system effects are more likely at high doses in patients with renal impairment. Acyclovir is Pregnancy Category B — it is not known to cause fetal harm at therapeutic doses, but should be used in pregnancy only when clearly needed. Breastfeeding safety is generally considered acceptable.
Side effects of Acyclovir 400mg
Acivir 400mg DT is generally well tolerated. The most commonly reported side effects include nausea, vomiting, diarrhoea, and abdominal discomfort. Headache and dizziness occur occasionally. Renal impairment may occur, particularly with inadequate hydration or in patients with pre-existing renal disease — drink plenty of fluids. Elevated creatinine and blood urea nitrogen have been reported. Neurological effects — including tremor, confusion, agitation, and seizures — are rare and most commonly occur at high intravenous doses or in renally impaired patients. Skin rash and photosensitivity are occasionally reported. Haematological effects, including leucopenia and thrombocytopenia, have been observed rarely.
Benefits of Buying Acivir 400mg DT Online from AllDayChemist
AllDayChemist provides discreet, affordable access to genuine Acivir 400mg DT from Cipla at prices well below branded Zovirax alternatives. The sensitive nature of herpes management makes AllDayChemist’s private, home-delivery model particularly valuable for patients. Worldwide shipping, a convenient prescription upload process, and competitive pricing make us the trusted platform for reliable antiviral therapy supply. Click to access a wide range of HIV antiretrovirals and herpes treatment medicines.
Proper dosage and usage guide of Acyclovir 400mg DT
The tablet can be swallowed whole with water, or dispersed in at least 50ml of water and drunk immediately. For initial genital herpes: 400mg three times daily for 5–10 days, starting as soon as possible after symptom onset. For recurrent genital herpes: 400mg three times daily for 5 days. For suppressive therapy: 400mg twice daily, taken every day. For herpes labialis: 400mg five times daily for 5 days. Take with or without food — food does not significantly affect absorption. Maintain adequate hydration throughout treatment. Store at room temperature (15–30°C) in a dry, light-protected place.
What is Acivir Dispersible Tablets 400mg used for, and why do doctors recommend it for anti viral?
Acivir Dispersible Tablets 400mg contain acyclovir, which treats viral infections caused by herpes simplex virus and varicella zoster virus. Doctors recommend it because it stops viruses from multiplying in your body, reducing infection severity and duration. It works against cold sores, genital herpes, chickenpox, and shingles. The dispersible tablet form dissolves easily, making it convenient to take and suitable for patients who have difficulty swallowing regular tablets. This formulation helps your body fight the infection more effectively.
How does Acivir Dispersible Tablets 400mg treat Anti Viral, and what does it do inside the body?
Acyclovir works by entering infected cells and blocking the virus's ability to copy itself. The virus needs an enzyme to reproduce, and acyclovir stops this process. Without reproduction, the virus cannot spread to healthy cells or worsen your infection. Your immune system then clears the weakened virus more easily. This speeds recovery and reduces symptoms like pain, blistering, and itching. The tablet dissolves in your mouth or water, allowing faster absorption into your bloodstream for quicker action.
When is the best time of day to take this tablet, and does it matter?
Take Acivir Dispersible Tablets 400mg with water, with or without food, at evenly spaced intervals throughout the day. Your doctor will tell you the exact timing and number of doses. Spacing doses evenly is more important than taking them at a specific time. For example, if you take five doses daily, space them roughly four to five hours apart. Taking it at the same times each day helps you remember. Follow your doctor's instructions precisely for best results.
Will this tablet affect my ability to drive a car or concentrate at work?
Acivir Dispersible Tablets 400mg rarely cause drowsiness or affect concentration in most people. However, some patients report dizziness, confusion, or headaches, especially at higher doses or with existing kidney problems. If you experience these side effects, avoid driving or operating machinery until you feel normal. Always wait after your first dose to see how your body responds. If side effects concern you, contact your doctor before driving or working with heavy equipment.
Does the dose need to change if I have kidney or liver problems?
Yes, kidney problems require dose adjustments because acyclovir passes through your kidneys. If your kidney function is reduced, your doctor will lower your dose to prevent the medicine from building up in your body. Liver problems are less critical since acyclovir doesn't rely on your liver for processing. Tell your doctor about any kidney disease, dialysis, or reduced kidney function before starting treatment. Your doctor will test your kidney function and adjust your dose safely based on results.
What should I do if this tablet upsets my stomach or makes me feel sick?
Take Acivir Dispersible Tablets 400mg with food if stomach upset occurs. Drinking plenty of water helps flush the medicine through your system and reduces nausea. If nausea continues or worsens, contact your doctor or pharmacist for advice. They may recommend anti-nausea medicine or suggest taking doses at different times. Never stop taking the tablet without permission, as incomplete treatment allows the virus to resist the medicine and worsen your infection.
How long before I notice a difference with Acivir Dispersible Tablets 400mg, and what will I feel?
Most people notice symptom relief within two to three days of starting treatment, though this varies. Pain, tingling, and itching typically decrease first. Blisters may crust over and heal within five to ten days. Complete healing takes one to two weeks depending on infection severity. Starting treatment early gives best results. If you see no improvement after five days, contact your doctor to confirm the diagnosis and check if the medicine is working properly.
What should I watch out for while using Acivir Dispersible Tablets 400mg, and when should I call my doctor?
Watch for signs of kidney problems like reduced urination, swelling in legs and feet, or extreme fatigue. Report severe headaches, confusion, hallucinations, or difficulty concentrating immediately. Some patients experience allergic reactions with rash, itching, or swelling of lips and tongue. Stop the medicine and seek urgent care if you have severe reactions. Also report persistent diarrhea, vision changes, or tremors. Drink plenty of water daily to protect your kidneys during treatment.
Is Acivir Dispersible Tablets 400mg just as good as the original brand-Zovirax?
Acivir Dispersible Tablets 400mg contain the same active ingredient as the original brand, Zovirax, and work identically in your body. Both contain acyclovir 400mg and meet the same quality and safety standards. The main difference is the dispersible form makes Acivir easier to take and absorb. Independent testing confirms Acivir reaches your bloodstream effectively and produces the same antiviral effects. Your doctor or pharmacist can confirm this is a safe, effective alternative to the brand-name product.
How long will my doctor keep me on Acivir Dispersible Tablets 400mg, and what happens if I stop?
Treatment duration depends on your infection type and severity. Acute infections like chickenpox typically last seven to ten days. Herpes outbreaks usually need five to ten days of treatment. For recurring infections, your doctor may prescribe longer-term preventive dosing. Stopping early allows the virus to survive and cause relapse or resistance. Never stop without doctor approval. If your symptoms improve before treatment ends, continue taking the full course as prescribed to completely eliminate the virus.
How does Acivir Dispersible Tablets 400mg compare to valacyclovir, and when would a doctor choose one over the other?
Both acyclovir and valacyclovir treat herpes viruses effectively, but valacyclovir requires fewer daily doses. Acyclovir needs three to five doses daily, while valacyclovir typically needs two to three. Acyclovir dispersible tablets are easier to swallow and work well for patients who prefer multiple daily doses. Valacyclovir suits patients wanting less frequent dosing. Cost and kidney function also influence the choice. Your doctor selects based on your infection type, kidney health, and ability to remember doses consistently throughout the day.
Are there any diet, exercise, or lifestyle changes that can help Acivir Dispersible Tablets 400mg work better?
Drink plenty of water daily to support kidney function and help your body eliminate the medicine efficiently. Eat a balanced diet with adequate protein and vitamins to strengthen your immune system during recovery. Avoid touching or scratching blisters to prevent spreading infection to other body areas. Get adequate rest to allow your immune system to fight the virus effectively. Avoid triggers like stress and excessive sun exposure if you have recurrent herpes. These habits improve treatment outcomes but don't replace your medicine.
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign Up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Forgot Password ?