Adalat Chrono 30mg
Out Of Stock
| SKU: | 737 |
|---|---|
| Active Ingredient: | Nifedipine |
| Manufacturer: | Bayer healthcare, Germany |
Nifedipine is known as a calcium channel blocker drug which dilates (relaxes and widens) blood vessels (veins and arteries) making it easier for the heart to pump blood and lower its workload. This medicine is prescribed for the treatment of hypertension (high blood pressure) and angina (chest pain). It may also be used for other purposes not listed here.
Nifedipine is sold under various trade names, some of which are Procardia, Myogard (made by UPM), Nicardia (made by Unique), Nifelat (made by Cipla), and Adalat Chrono (made by Bayer Healthcare).
Important Information about Nifedipine
Do not take Nifedipine (Procardia, Myogard, Nicardia, Nifelat, and Adalat Chrono) if you are allergic to it. Before taking this medication, let your doctor know if you are allergic to it or to other drugs, if you have ever had heart disease (congestive heart failure), liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, or hypothyroidism.
Before having a surgery or any medical procedure, inform your doctor or other healthcare personnel that you are taking Nifedipine. This medication may make you dizzy. Do not drive or do any such activities which require a great deal of alertness until you are sure that you can do them safely. Limit or avoid alcohol consumption.
Nifedipine is classfied as an FDA pregnancy category C drug. It is not known whether this medication can harm an unborn baby if taken during pregnancy. This medication can pass into breast milk and harm a nursing baby. You must consult your doctor before using this medication if you are pregnant or breast feeding.
Before taking Nifedipine
Prior to taking Nifedipine, you must tell your doctor if you have any of the following conditions: kidney disease, liver disease (especially cirrhosis), a blockage in the digestive tract (stomach or intestines), inflammatory bowel disease, diverticulitis, chronic constipation, a colostomy or a history of stomach surgery such as gastric bypass, colon cancer, hypothyroidism, coronary artery disease, or congestive heart failure. This is for the doctor to judge whether it is safe for you to take this medication.
Extended release tablets of Nifedipine may contain lactose. Let your doctor know if you are lactose intolerant.
How should I take Nifedipine?
Take Nifedipine strictly according to your doctor’s directions or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Also, do not take this medication after the prescribed period is over. All medications come with a patient leaflet. Refer the instructions in them for detailed information on that particular medication. Nifedipine can be taken with or without food. Always store this medicine in a cool and dry place.
Do not break, crush, or chew an extended release tablet of Nifedipine. Instead, swallow it whole. Breaking, crushing, or chewing an extended release tablet may cause too much of the drug to be release in a short time. Let your doctor know if you have excessive sweating, vomiting or diarrhea. These conditions can cause severe low blood pressure.
Some tablet forms of Nifedipine are made with a shell that is not absorbed or melted in the body and gets excreted in the stool. This is normal and not a reason to worry.
What if I miss a dose?
You should take all medication on time as prescribed. Missing even a single dose can be harful in certain cases. If you miss a dose of fo Nifedipine, then take it at the instant you remember it. However, you must skip the missed dose if the time to take the next scheduled dose is near.
What if I overdose?
In case of an overdose of Nifedipine, get emergency medical attention or call the Poison helpline at 1-800-222-1222. Overdose may lead to severe dizziness, pounding heartbeats, nausea, vomiting, or feeling like you might pass out.
Things and Activities to avoid while taking Nifedipine
Alcoholic beverages must be avoided while taking this medicine as alcohol can further lower blood pressure. Also avoid activities which require a high level of mental awareness and reflexes (such as driving). Do not consume grapefruit or grapefruit based products as they can interact with Nifedipine and cause potentially dangerous effects.
Nifedipine Side Effects
Some common side effects of Nifedipine are dizziness, flushing, weakness, swelling in ankles or feet or headache. If any of these effects persist or deteriorate, get medical attention right away.
Nifedipine can rarely worsen chest pain or cause heart attack in some people who already have severe heart disease. This happens after starting this medication or increasing the dose. Get medical attention right away if you experience worsening chest pain or the first sign of heart attack (pain in chest/jaw/left arm, shortness of breath, or unusual sweating.
All information includind that of side effects is limited in this guide. If you experience other side effects and think that they are serious, seek medical attention right away. FDA has a helpline for reporting side effects. You can report your side effects (recommended) by calling the helpline at 1-800-FDA-1088 (toll free).
Nifedipine Dosing Information
Nifedipine dosage may depend on a range of factors like age, sex, drug allergies, or seriousness of the condition among several other factors. Your dosage will be determined by your doctor after examining you properly. Remember to follow your doctor’s advice properly for best results.
Interaction with other drugs
Many other drugs can interact with Nifedipine. Let your doctor know in advance if you use any other drugs or related products (OTC vitamin pills or other medicines, or herbal products), especially cemitidine, conivaptan, digoxin, fentanyl, imatinib, isoniazid, laxatives, levothyroxine, nefazodone, NSAIDs (ibuprofen, naproxen, or others), cold or allergy medications, tizanidine, St.John’s Wort, HIV/AIDS medicines, antibiotics (clartithromycin, erythromycin, or others), or seizure medicines. Remember that the information provided here is very limited. There may be other interacting drugs. Do not start or stop any medications without proper medical advice.
What is Adalat Chrono 30mg used for?
Adalat Chrono 30mg is the branded formulation of Nifedipine 30mg using Bayer's Chronotherapeutic Oral Drug Absorption System (CODAS) or GITS technology. It provides controlled, once-daily delivery of Nifedipine for the prevention of angina and treatment of hypertension. As an originator Bayer product, it is widely recognised by cardiologists and used in landmark clinical trials that established Nifedipine GITS as a guideline-recommended antihypertensive.
How does Adalat Chrono 30mg improve on immediate-release Nifedipine?
Adalat Chrono 30mg uses extended-release technology to deliver Nifedipine continuously over 24 hours from a single morning dose. This eliminates the sharp plasma concentration peaks of immediate-release Nifedipine that cause reflex tachycardia, flushing, and headache. The smoother drug delivery profile provides stable blood pressure control throughout the day and is associated with superior cardiovascular outcomes compared to older short-acting Nifedipine formulations.
What is the dose schedule for Adalat Chrono 30mg?
Adalat Chrono 30mg is taken once daily in the morning, swallowed whole with a glass of water. Do not crush or chew. It can be taken with or without food. If blood pressure is not adequately controlled on 30mg, the dose may be increased to 60mg once daily. The maximum approved dose is 90mg once daily for hypertension and 120mg for some angina presentations — all under cardiologist guidance.
Can Adalat Chrono 30mg be used for Raynaud's disease?
Yes. Nifedipine is one of the most effective treatments for Raynaud's phenomenon and is used off-label for this indication. By relaxing peripheral arteriolar smooth muscle, Nifedipine reduces the frequency and severity of cold-triggered vasospastic attacks in Raynaud's. The GITS formulation with gradual drug release provides more consistent peripheral vaSodiumilation than immediate-release Nifedipine, making Adalat Chrono 30mg a practical choice for Raynaud's management.
Is Adalat Chrono 30mg safe in pregnancy-induced hypertension?
Nifedipine is one of the most used calcium channel blockers for hypertension in pregnancy (second and third trimester), as well as for tocolysis (delaying preterm labour). The CHIPS trial established that tight blood pressure control with Nifedipine (or Labetalol) in pregnancy reduces severe maternal hypertension without harming the fetus. Adalat Chrono 30mg should be used in pregnancy only under obstetric/maternal-fetal medicine specialist guidance.
Can Adalat Chrono 30mg be used with magnesium sulphate?
Caution is required. The combination of Nifedipine and magnesium sulphate (commonly used in pre-eclampsia) can cause excessive neuromuscular blockade, hypotension, and cardiac depression in some cases. This interaction is clinically important in obstetric settings. If both are needed simultaneously, close monitoring of blood pressure, heart rate, and neuromuscular function is mandatory. This combination should only be managed by experienced obstetric specialists.
How does Adalat Chrono 30mg compare to generic Nifedipine CD 30mg?
Adalat Chrono 30mg (Bayer) is the originator brand. Generic Nifedipine CD 30mg formulations are bioequivalent generics providing the same controlled delivery and antihypertensive effect. AllDayChemist offers both Adalat Chrono 30mg (branded) and equivalent generic Nifedipine CR/CD at competitive prices, allowing patients to choose between the originator and the generic based on preference and cost.
Is Adalat Chrono 30mg more expensive than generic alternatives?
Branded Adalat Chrono 30mg is priced higher than generic Nifedipine CR/CD products. However, Bayer's Adalat Chrono is available at AllDayChemist at prices significantly lower than US or UK retail for this brand. For patients who prefer the originator brand or whose physician specifically prescribes Adalat Chrono, AllDayChemist provides competitive pricing with international shipping.
Can I buy Adalat Chrono 30mg from AllDayChemist?
Yes. Adalat Chrono 30mg is available at AllDayChemist with worldwide shipping to the USA, UK, Australia, and more countries. AllDayChemist has operated since 2002, providing authentic branded and generic medicines. Orders ship in discreet, plain packaging with tracking. Free shipping is available on qualifying orders. Visit AllDayChemist.com.
Why buy Adalat Chrono 30mg from AllDayChemist?
AllDayChemist offers Adalat Chrono 30mg at prices below Western retail for this Bayer brand. Since 2002, AllDayChemist has served 200+ countries with authentic, manufacturer-sourced branded medications. Free international shipping on qualifying orders, discreet packaging, and reliable tracking make AllDayChemist an attractive option for patients who prefer the originator Adalat Chrono brand at a more competitive price.
What side effects does Adalat Chrono 30mg cause?
Peripheral oedema (ankle swelling) is the most common side effect of Nifedipine GITS/Chrono formulations. Headache, flushing, and dizziness are less frequent than with immediate-release Nifedipine. Reflex tachycardia is minimal with the controlled-release formulation. Constipation is uncommon with dihydropyridine CCBs. Gingival overgrowth can occur with long-term use. The empty tablet shell in stool is a normal GITS occurrence — not a sign of treatment failure.
What precautions apply to Adalat Chrono 30mg?
Swallow whole. Avoid grapefruit. Do not combine with strong CYP3A4 inhibitors without dose adjustment. Use caution in severe aortic stenosis and cardiogenic shock. Do not use in cardiogenic shock, unstable angina of cardiac origin (without beta blocker), or in patients with obstructive bowel disease (the GITS shell may obstruct). Inform your surgeon and anaesthetist about Nifedipine use. Ankle oedema can be managed with leg elevation — rarely requires discontinuation.
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