Available Dosages
| SKU: | 82 |
|---|---|
| Generic For: | Finacea Cream |
| Active Ingredient: | Azelaic Acid |
| Manufacturer: | Micro Lab, India |
Buy Aziderm Cream 20 % (15gm) (Azelaic Acid) for Acne & Rosacea
Aziderm Cream 20% is a prescription-strength topical formulation containing Azelaic Acid 20%, used in the treatment of moderate to severe acne vulgaris, rosacea with inflammatory lesions, and persistent post-inflammatory hyperpigmentation. Manufactured by Glenmark Pharmaceuticals, it delivers the maximum approved topical concentration of Azelaic Acid. It is recommended when lower-strength formulations have provided insufficient results or when the clinical presentation warrants more aggressive topical management. With a well-established mechanism of action spanning antibacterial, comedolytic, and skin-tone-normalizing effects, Aziderm Cream 20% is a cornerstone of medical-grade acne and pigmentation therapy.
What is Aziderm Cream 20%?
Aziderm Cream 20% is a topical cream containing Azelaic Acid 20% per gram of cream. It is the higher-strength variant in the Aziderm range and is indicated for patients requiring more substantial Azelaic Acid exposure than the 10% formulation provides. At this concentration, the antibacterial, anti-comedonal, and tyrosinase-inhibiting properties of Azelaic Acid are maximized, making it one of the most evidence-backed topical treatments available for adult acne, papulopustular rosacea, and melasma. The cream base is suitable for normal to dry skin types; patients with oily skin may prefer a gel formulation if available. The 15g tube delivers a clinically appropriate quantity for facial application over a treatment course of several weeks.
Manufacturer: Aziderm Cream 20% is manufactured by Glenmark Pharmaceuticals Ltd., a globally respected Indian pharmaceutical company with a leading dermatology division, internationally accredited manufacturing facilities, and a broad portfolio of evidence-based skin care products distributed across multiple regulated markets.
Key Ingredients of Aziderm Cream 20% and Their Working Process
Azelaic Acid 20% works through several interconnected mechanisms that address the root causes of acne and skin discolouration with a depth and breadth unmatched by single-mechanism topical agents. At the 20% concentration, its antibacterial activity against Cutibacterium acnes (formerly Propionibacterium acnes) is substantially stronger than at lower concentrations, achieved by inhibiting bacterial protein synthesis through interference with the thioredoxin reductase enzyme system—a pathway entirely distinct from conventional antibiotics, meaning resistance does not develop. This makes Aziderm 20% particularly valuable in patients who have developed resistance to topical Clindamycin or Erythromycin following prolonged antibiotic use.
The comedolytic action of Azelaic Acid at 20% is driven by normalization of the hyperkeratosis in the follicular canal — the process by which excess dead skin cells accumulate inside pores and combine with sebum to form comedones. By regulating keratinocyte differentiation and reducing the excessive stickiness of desquamating cells within the follicle, Azelaic Acid 20% unblocks existing comedones and prevents new ones from forming. Its potent tyrosinase inhibition at this concentration delivers more aggressive lightening of hyperpigmented areas — including melasma, post-inflammatory hyperpigmentation, and acne-related dark marks — by reducing melanin synthesis in overactive melanocytes. Importantly, Azelaic Acid selectively targets abnormally active melanocytes without depigmenting normally pigmented skin, making it safer for use on skin of colour than hydroquinone-based preparations.
Clinical Uses of Azelaic Acid 20%
Azelaic Acid 20% is clinically indicated as a first-line treatment for moderate acne vulgaris in adults and adolescents, and as a second-line option in mild acne where resistance to antibiotics or intolerance to retinoids is a factor. International dermatology guidelines (including those of the European Dermatology Forum) recognize Azelaic Acid 20% as an evidence-based option for acne, with a favourable safety and tolerability profile and suitability for long-term maintenance. It is particularly recommended for adult women with hormonally influenced acne, in whom concerns about antibiotic resistance and retinoid teratogenicity make Azelaic Acid an ideal choice.
For papulopustular rosacea — characterized by inflammatory acne-like papules and pustules on a background of facial redness — Azelaic Acid 20% is considered a first-line treatment in multiple clinical guidelines. It significantly reduces the inflammatory lesion count, with visible improvement typically observed after 12 weeks of twice-daily application. In the management of melasma and post-inflammatory hyperpigmentation, the 20% concentration provides a more pronounced, faster brightening effect than the 10% concentration, making it preferred for patients with moderate-to-severe pigmentation concerns.
Comparing Aziderm Cream 20% and Skinoren 20%: Brand vs Generic Differences
Aziderm Cream 20% and Finacea 20%, both contain azelaic acid and are used to treat acne, pigmentation, and rosacea by reducing bacteria, inflammation, and clogged pores. Finacea is a branded formulation widely recognized in international markets, while Aziderm Cream 20% is a more affordable generic alternative commonly available in India. Both products provide similar therapeutic effects because they contain the same active ingredient at the same strength, but they may differ in texture, inactive ingredients, packaging, and manufacturer standards. Some users may notice differences in skin absorption, irritation levels, or overall skin feel. Aziderm is often preferred for cost-effective long-term treatment, whereas Finacea may be chosen for brand preference or dermatologist recommendation. Consistent use under medical guidance is important for achieving the best results with either product.
Related strengths and products: Patients beginning Azelaic Acid therapy may prefer to start with Aziderm Cream 10% 15g to assess skin tolerance before escalating to the 20% strength. For combination acne management, Acnesol Gel 1% (Clindamycin topical antibiotic) or Adaferin Gel 0.1% (Adapalene retinoid) can be used alongside Azelaic Acid under dermatologist guidance to address different components of acne pathogenesis.
Key Benefits of Aziderm Cream 20%
Aziderm Cream 20% delivers the highest clinically validated topical dose of Azelaic Acid, maximizing its triple-action effect against acne, rosacea, and pigmentation simultaneously. As a non-antibiotic antibacterial, it eliminates the risk of inducing resistance in acne-causing bacteria — a growing concern with prolonged topical antibiotic use — and can be used continuously for months to years without this limitation. Unlike topical retinoids, it is not photosensitizing, allowing both morning and evening application without mandatory sun avoidance, though daily SPF use remains recommended for patients managing hyperpigmentation. It is safe for use in adult women who are pregnant or considering pregnancy — a significant advantage over retinoids, which are teratogenic. Its selective action on abnormally pigmented melanocytes means it lightens dark spots without bleaching normally pigmented surrounding skin, making it safe and effective for patients with darker skin tones who are prone to both acne and post-inflammatory hyperpigmentation.
Usage warnings and precautionary advice for using Azelaic Acid 20%
Aziderm Cream 20% is for external use only. Avoid application to the eyes, broken skin, or mucous membranes. An initial burning or stinging sensation is common and typically resolves within the first two to four weeks of use; if it is severe or persistent, consider starting with the 10% strength and escalating after tolerance is established. Patients with known hypersensitivity to Azelaic Acid or to any excipient in the formulation should not use this product. Although Azelaic Acid is considered Pregnancy Category B and is used in pregnancy for rosacea management in some clinical settings, use during pregnancy or lactation should be reviewed with a physician. Avoid contact with dyed fabrics such as clothing and bed linen, as Azelaic Acid may cause minor staining.
Side effects of Azelaic Acid 20%
The side effects of Aziderm Cream 20% are primarily localized to the application site. Burning, stinging, tingling, and itching are the most commonly reported effects and are dose-related — they are more frequent at the 20% concentration than at 10%, particularly in the first few weeks of treatment. Skin dryness, scaling, and mild peeling may also occur, especially in patients with already sensitive or dry skin. These effects generally resolve within a month of consistent use as the skin adapts. Expected therapeutic lightening of hyperpigmented areas should not be confused with a side effect. Rare cases of allergic contact dermatitis have been reported, presenting as widespread redness, swelling, and urticaria beyond the application site. Hypopigmentation at the application site, while rare at standard concentrations, has been reported in patients with darker skin tones who use high-strength formulations for extended periods.
Benefits of Buying Aziderm Cream 20% Online
AllDayChemist provides genuine Glenmark-manufactured Aziderm Cream 20% at highly competitive prices, offering patients with long-term acne, rosacea, or pigmentation concerns a cost-effective and reliable supply channel. The discreet packaging and international delivery available through AllDayChemist make it easy to maintain consistent treatment — critical for conditions that require months of continuous topical therapy. Check a wide dermatology catalogue, including moisturizers, SPF creams, and combination acne treatments, all in one place.
Proper dosage and usage guide of Azelaic Acid 20% Cream
Aziderm Cream 20% should be applied twice daily — morning and evening — to clean, dry skin. A thin layer of cream should be gently massaged into the affected areas of the face or body until fully absorbed; avoid the eye area, nostrils, and mouth. Wash hands thoroughly after application. In patients who experience significant burning or dryness on initiation, the frequency can be reduced to once daily for the first two weeks before advancing to twice daily. Improvement in acne is typically visible after four to eight weeks, while results for pigmentation and rosacea may take eight to twelve weeks of consistent use. Daily SPF 30+ sunscreen use in the morning is strongly recommended for optimal pigmentation outcomes. Store at room temperature below 25°C, away from light and moisture.
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