Duphaston 10 mg should not be used under the following conditions:

   — Known allergy to dydrogesterone or any of the ingredients present in the medicine

   — Known or suspected sex hormone-dependent malignancies

   — Presence of serious liver disorders

   — Vaginal bleeding where the cause has not been identified

   — Contraindications for the use of estrogens along with progestogens such as dydrogesterone in combined therapy. 

Caution should be taken before starting treatment with dydrogesterone because of dysfunctional uterine bleeding; an organic cause should be excluded. Breakthrough bleeding and frequent spotting may occur during the initial months of treatment. 

If any of the following conditions occur during use for the first time or get worse, consider stopping the treatment:

• A significant increase in the blood pressure
• Occurrence of venous thromboembolism

Severe headaches, migraine, or symptoms may indicate cerebral ischemia. 

Common side effects of Duphaston 10 mg are headache, migraine, breast pain, feeling dizzy, being sick, and feeling depressed. Stop taking medicine and see a doctor immediately if you develop serious issues like liver problems and allergic reactions. 

The following dosing regimen is recommended for treatment with Duphaston. The number of tablets can be adjusted according to the severity of the condition to be treated and the patient’s responses to the treatment. If you have periods, day one of your cycle is when you start bleeding. If you do not have periods, your doctor will decide with you when to start day one of the cycle and when to start taking your tablets. Swallow the tablet with water. You can take them before or after consuming food. Talk to your doctor to get the correct dosing regimen for you.