Available Dosages
| SKU: | 678 |
|---|---|
| Active Ingredient: | Metronidazole |
| Manufacturer: | Abbott Healthcare, India |
Buy Flagyl 400mg (Metronidazole) Antibiotic for Infections
Flagyl 400mg is a widely prescribed antibiotic and antiprotozoal medication used to combat a broad spectrum of bacterial and parasitic infections. It contains Metronidazole as its active ingredient. Flagyl has been an essential medicine on the WHO Model List of Essential Medicines for decades. It is recognised globally for its efficacy and safety in treating infections of the reproductive tract, gastrointestinal system, skin, joints, and respiratory tract.
What is Flagyl 400mg?
Flagyl 400mg is an oral antibiotic tablet containing 400mg of Metronidazole. It belongs to the nitroimidazole class of antibiotics and exerts potent action against a wide range of anaerobic bacteria and protozoan parasites. It is a prescription medication used to treat infections that ordinary antibiotics cannot adequately address, particularly those caused by anaerobic organisms that thrive in low-oxygen environments. Flagyl is not effective against viral infections such as the common cold or influenza, nor is it suitable for treating vaginal yeast infections. For more information about the importance of antibiotics, talk to your healthcare professional.
Manufacturer information: Flagyl 400mg is manufactured and marketed by Abbott India Ltd. Abbott is a globally recognised pharmaceutical company known for producing quality healthcare and prescription medicines.
The mode of action of Metronidazole (active ingredient)
The active ingredient in Flagyl 400mg is Metronidazole. Once absorbed, Metronidazole is taken up by anaerobic bacterial and protozoal cells. Inside these microorganisms, it is chemically activated, disrupting the helical structure of DNA and thereby inhibiting nucleic acid synthesis and causing cell death. This mechanism is highly selective for anaerobic organisms because they lack the antioxidant defences that aerobic human cells possess, making Metronidazole an effective and targeted antibiotic. It is bactericidal (kills bacteria) rather than merely bacteriostatic (inhibiting growth).
Clinical uses of Metronidazole
Flagyl 400mg is used to treat a wide range of infections. These include bacterial vaginosis, trichomoniasis (a sexually transmitted infection), Helicobacter pylori-associated peptic ulcers (often in combination with other antibiotics and a proton pump inhibitor), amoebiasis (intestinal infection caused by Entamoeba histolytica), giardiasis (intestinal infection caused by Giardia lamblia), anaerobic soft tissue infections, intra-abdominal infections, liver abscess, and dental infections. It is also used as a prophylactic antibiotic before certain surgical procedures.
Related strengths & products: Metrogyl 200mg for milder infections, standard treatment. Other topical metronidazole combinations include Roza gel 30mg.
Key benefits of Flagyle 400mg
Flagyl 400mg offers broad-spectrum coverage against anaerobic bacteria and many protozoa, making it one of the most versatile antibiotics available. It is highly bioavailable when taken orally, achieving rapid, effective tissue concentrations. The medication has a well-established safety profile developed over many decades of clinical use worldwide. It is available in an affordable generic form, providing cost-effective treatment. Its efficacy against H. pylori makes it a cornerstone of triple therapy for peptic ulcer disease, and its antiprotozoal action makes it uniquely suited for infections such as amoebiasis and giardiasis that other antibiotics cannot treat.
Precautions and risk information associated with Metronidazole
Flagyl is contraindicated in patients with a history of allergy to Metronidazole or other nitroimidazoles. It should not be taken during the first trimester of pregnancy due to potential risks to foetal development. Women who are breastfeeding should inform their doctor, as Metronidazole passes into breast milk. Patients with a history of liver disease, neurological conditions, blood disorders such as anaemia or leukopenia, epilepsy, or Crohn's disease should inform their doctor before use, as special monitoring or dose adjustments may be needed. Metronidazole interacts significantly with alcohol, causing a severe disulfiram-like reaction; alcohol must be avoided throughout the course and for 72 hours after completion. It may also interact with warfarin (potentiating its anticoagulant effect), lithium, phenytoin, and busulfan. Antibiotic-associated diarrhoea, which may signal a Clostridioides difficile infection, should be reported to a doctor promptly. Do not self-medicate with antidiarrhoeal drugs unless specifically advised by your physician.
Side effects associated with Metronidazole
Many patients tolerate Flagyl 400mg without significant side effects. However, some patients may experience gastrointestinal symptoms such as nausea, vomiting, stomach cramps, diarrhoea, loss of appetite, and a bitter or metallic taste in the mouth. These are among the most frequently reported complaints, but are often manageable by taking the medication with food. Neurological side effects, though less common, can occur and include headache, dizziness, and tingling or numbness in the extremities — a sign of peripheral neuropathy that warrants prompt medical attention. Serious but rare effects include seizures, encephalopathy, confusion, and mood changes. Dark or reddish-brown urine discolouration is a recognised harmless effect of metronidazole metabolism. Severe skin reactions, including Stevens-Johnson syndrome, are extremely rare. Any signs of an allergic reaction — hives, breathing difficulty, or facial swelling — require immediate emergency care.
Buy genuine antibiotics online
Purchasing Flagyl 400mg online through AllDayChemist provides significant convenience and financial savings. Prices are considerably lower than those for branded or retail alternatives in many countries. The platform offers genuine Flagyl, ensuring quality and consistency. Ordering online is discreet and practical, particularly for conditions involving the reproductive or gastrointestinal tract. Home delivery eliminates the need to visit a pharmacy while unwell. AllDayChemist supports secure prescription uploads, ensuring a safe, compliant dispensing process. For patients who have received a repeat prescription, online purchasing simplifies maintaining uninterrupted treatment.
Dosing information and administration protocol for using Metronidazole
Flagyl 400mg should be taken exactly as prescribed by your doctor. Do not alter the dose or duration without medical advice. The tablet is typically taken on an empty stomach, at least one hour before or two hours after eating, though it may be taken with food if it causes stomach upset. Swallow the tablet whole; do not crush, chew, or break it, as this could lead to a higher-than-intended amount of the drug being released at once.
The dosage and duration of antibiotic tablets vary depending on the type of infection being treated. Common regimens include 400mg two to three times daily for 5 to 10 days for most bacterial and protozoal infections. Always complete the full course of treatment, even if you start feeling better early, as stopping prematurely can lead to drug-resistant infections that are harder to treat.
Do not consume alcohol during metronidazole treatment or for at least 72 hours after the course ends, as this combination can cause a severe disulfiram-like reaction characterised by nausea, vomiting, flushing, and palpitations. Store at room temperature (15–30°C), away from light and moisture.
Can I drink alcohol while taking Flagyl 400mg?
No. Alcohol must be strictly avoided during the entire course and for at least 72 hours after finishing Flagyl, as it can cause a severe and unpleasant reaction, including vomiting, flushing, and rapid heartbeat.
What infections does Flagyl 400mg treat?
Flagyl 400mg treats bacterial vaginosis, trichomoniasis, amoebiasis, giardiasis, H. pylori infection, intra-abdominal infections, dental infections, and anaerobic soft tissue infections, among others.
Is Flagyl safe to use in pregnancy?
Flagyl is generally avoided in the first trimester. For the second and third trimesters, it may be used if the benefits clearly outweigh the risks. Always consult a doctor.
How long does a Flagyl course typically last?
The duration depends on the infection. Most courses last 5 to 10 days. Complete the full prescribed course even if symptoms resolve early.
Why should I not stop Flagyl before completing the course?
Stopping early may leave residual bacteria partially exposed to the drug, potentially creating antibiotic-resistant strains that are more difficult to treat in the future.
Can Flagyl be taken with food?
Flagyl is ideally taken on an empty stomach. However, if it causes significant stomach upset, taking it with food is acceptable and does not meaningfully reduce its effectiveness.
Does Flagyl treat yeast infections?
No. Flagyl is not effective against Candida yeast infections. It should not be used to treat vaginal thrush; an antifungal medication such as Fluconazole is appropriate for yeast infections.
Is a prescription required to purchase Flagyl online?
Yes. Flagyl 400mg is a prescription antibiotic. You will need to upload a valid doctor's prescription when ordering through AllDayChemist.
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