Leading Online Pharmacy
100% Genuine Products
  Wide Collection of Prescription
& OTC Products
  We Accept eCheck
Secure and Faster payment gateway

Istavel 100mg
Upto 7% OFF

Istavel 100 mg Contains Sitagliptin is a prescription medicine used for the treatment of type 2 Diabetes

$0.65 - $0.70

Rating:
96% of 100

Available Dosages

50 Tablet/s
US$ 0.70 - Price Per Tablet
US$ 35.00
100 Tablet/s
US$ 0.65 - Price Per Tablet
US$ 65.00US$ 70.00
More Information
SKU: 1012
Generic For: Januvia
Active Ingredient: Sitagliptin
Manufacturer: Sun Pharma
Customer Reviews
Write Your Own Review

Buy Istavel 100mg (Sitagliptin) for Type 2 Diabetes

Istavel 100 mg tablet is an oral medication for treating type 2 diabetes. It is recommended together with a balanced diet and regular exercise to control blood sugar levels in the body. It is usually recommended alone or in combination with other medicines that treat diabetes. This medicine is not recommended to treat type 1 diabetes. Istavel helps prevent serious health complications of diabetes, such as kidney failure and vision blindness.

Sitagliptin 100mg (DPP-4 inhibitors) is the main active ingredient (salt) of Istavel. It is marketed as a salt of phosphate under various brand names. It is one of the most effective medicines for controlling diabetes by regulating blood sugar levels.

This medicine is available in varying strengths, including 25mg, 50mg, and 100mg. Ask your doctor for the right dosage you need.

How does Sitagliptin 100mg tablet work? 

Istavel Sitagliptin works by lowering high blood glucose (hyperglycemia). This medicine increases the secretion of insulin and suppresses the release of glucagon by the pancreas. This drives the blood glucose levels to normal levels. As soon as the blood glucose levels become normal, the increased changes in insulin and glucagon stop, further preventing the hypoglycemic situation.

The usual starting dose for adults is one 100 mg tablet once a day; however, the drug dosage varies from person to person.

Precautions with Sitagliptin 100mg tablet

 

You should not take Istavel 100 mg if you are hypersensitive to Sitagliptin or other component of the drug. Pancreatitis or inflammation of the pancreas has been reported in patients receiving Istavel.

 

Before taking Sitagliptin, inform your doctor if you have ever had:

 

     ‒    Pancreatitis- a disease of the pancreas

     ‒    Type 1 diabetes

     ‒    Any past or present kidney problems

     ‒    An allergic reaction to Sitagliptin

     ‒    Diabetic ketoacidosis- a complication associated with diabetes, often accompanied by high blood pressure, nausea, vomiting, and rapid weight loss.

     ‒    Gallstones, alcohol dependence, or excessively high levels of triglycerides in your bloodstream

 

Istavel is less likely to cause hypoglycemia (low blood sugar) because it does not work when your blood sugar is too low. However, hypoglycemia episodes may occur when this drug is combined with insulin or sulfonylurea medicine. Your doctor may prescribe a reduced dose of insulin or sulfonylurea.   

 

Tell your doctor if you are taking any other medicine. In particular, if you are taking digoxin, which is used to treat irregular heartbeat and other heart diseases. The level of digoxin in your bloodstream may need to be checked if taken with Sitagliptin tablets.

 

If you are pregnant or breastfeeding, talk to your doctor for advice before taking this antidiabetic agent. You should avoid taking this medicine during pregnancy and breastfeeding, as it is unknown if it passes into breast milk.

Possible drug interactions

 

As the drug is associated with weight loss, ask your doctor about the intake of cholesterol and diabetes drugs. The following drugs may interact with Sitagliptin:

 

     ‒    Ivacaftor

     ‒    Probenecid

     ‒    Non-steroidal anti-inflammatory drugs

     ‒    Aspirin or other salicylates

     ‒    Sulfa drugs

     ‒    Monoamine oxidase inhibitors

     ‒    Beta-blockers

 

Ask your doctor to get the full list of drugs that need to be avoided while taking this medicine. Also, tell him about any herbal or OTC medicine you are currently taking or have taken. Never start a new medicine without consulting your doctor.

 

Things to be taken care of

 

     ‒    Your blood sugar will need to be checked often

     ‒    Do not consume alcohol

     ‒    Engage in regular exercise and follow a proper diet to monitor your blood sugar levels effectively.

     ‒    Keep a check on your body weight.

     ‒    Always keep a source of sugar available, such as fruit, candy, or gel.

     ‒    Keep the drug readily available; make timely purchases to avoid missing doses.

     ‒    Never change the dose or schedule of the medicine without doctor’s advice

     ‒    Do not skip meals while taking this drug.

 

Side effects of Sitagliptin 100mg tablet

 

Doctors usually prescribe the medicine after weighing the benefits against the risks you will get. The most common reported side effect of Istavel 100 mg is a headache. This is usually temporary and improves with time. Hypoglycemia (low blood sugar) is a possible side effect if you take other medicines like sulfonylurea or insulin. It is important to recognize the symptoms of hypoglycaemia and know how to deal with it. Contact your doctor if the side effects worry you or if they do not resolve within a few days.  

 

Some other less common side effects include unusual tiredness, fast heart rate, constipation, unusual bleeding or bruising, and soreness in the back of the nose.

 

Seek medical help when you experience any side effects. Do not get alarmed by the list; you may /may not experience these effects.

Usage instructions for the Sitagliptin 100mg tablet

 

You must always take this antidiabetic medicine exactly as told by your doctor. Speak to him if you are unsure how to take medicine. The usual recommended dose is 100 mg once a day. If you have renal impairment, your doctor may prescribe a lower dose. You can take this antidiabetic medicine before or after consuming food. Lifestyle modifications such as diet and regular exercise can help your body use its blood sugar better. Take a well-balanced, calorie-controlled diet rich in fruits and vegetables.

Swallow the tablet with one glass of water. Take this drug at the same time each day. This will help ensure you don’t forget to take the medicine at the correct time.

 

If you miss a dose, skip it and take the next one at the recommended time. If it’s too late, take it as you normally would, but within 1 hour of a meal. Do not double the dose to make up for the missed one. If you accidentally take too many tablets, contact your doctor immediately.

 

Continue to take the medicine as long as the doctor recommends. This medicine controls diabetes but does not cure it; hence, it needs to be taken for a longer time. The doctor will advise you on the duration for which you should take the medicine.

What is Istavel 100mg prescribed for, and which patients benefit most from it?

Istavel 100mg contains sitagliptin and treats type 2 diabetes by helping your body control blood sugar levels. Doctors prescribe it to patients whose blood sugar remains too high even after diet and exercise changes. It works best for people who need help managing their diabetes but may not yet require insulin injections. Your doctor will decide if this medicine suits your individual situation.

How does Sitagliptin work inside the body?

Sitagliptin helps your pancreas release the right amount of insulin when your blood sugar rises after eating. It does this by blocking an enzyme that normally breaks down natural hormones that control insulin release. This means your body produces insulin more efficiently and keeps blood sugar at safer levels throughout the day. The medicine works only when your blood sugar is elevated, reducing the risk of dangerously low blood sugar.

Food and alcohol: should I take this tablet with food, and is alcohol safe during treatment?

You can take Istavel 100mg with or without food, whichever suits you best. Taking it with a meal may reduce stomach upset if that occurs. Avoid drinking large amounts of alcohol while taking this medicine, as it may increase your risk of low blood sugar and affect your diabetes control. Talk to your pharmacist about safe alcohol limits for your personal situation.

How will I know the tablet is starting to work? What early changes should I look for?

Istavel 100mg works silently inside your body, so you may not feel immediate changes. The main sign of improvement is a lower blood sugar reading on your glucose monitor or blood tests. You might notice gradual improvements in energy levels or reduced thirst over weeks. Your doctor will check your blood sugar regularly to confirm the medicine is working as expected for you.

How should I store these tablets at home to keep them safe and effective?

Store Istavel 100mg tablets in a cool, dry place away from heat and direct sunlight. Keep them in their original container with the lid tightly closed. Do not store tablets in bathrooms where moisture from showers can damage them. Keep the medicine out of reach of children and pets. Always check the expiry date before taking any tablet.

What should I do if I accidentally take more tablets than prescribed?

If you take more Istavel 100mg than prescribed, contact your poison control center or emergency services immediately. Bring the medicine bottle with you so medical staff can see exactly what you took. Watch for signs of low blood sugar such as shakiness, sweating, dizziness, or confusion. Do not drive yourself to hospital; ask someone else to take you or call an ambulance.

How soon does Istavel 100mg start working, and what changes should I expect?

Istavel 100mg usually takes one to two weeks to show its full effects on blood sugar control. Some people notice improvements within a few days, while others take longer. You will not feel the medicine working directly, but your blood sugar readings will gradually improve. Your doctor will test your blood sugar after four to twelve weeks to check if the dose is right for you.

What are the most important safety warnings I need to know before taking Istavel 100mg?

Do not take Istavel 100mg if you are allergic to sitagliptin or have type 1 diabetes. Tell your doctor if you have kidney problems, as your dose may need adjustment. This medicine may rarely cause serious pancreas inflammation. Contact your doctor immediately if you have severe upper stomach pain, vomiting, or yellowing of skin and eyes during treatment.

How does Istavel 100mg compare to the brand Januvia and other treatments for Diabetes?

Istavel 100mg contains the same active ingredient as the brand Januvia and works in the same way in your body. Both are equally effective at controlling blood sugar. The main difference is cost, as Istavel is typically more affordable. Other diabetes medicines, like metformin or sulfonylureas, work differently, so your doctor chooses one based on your individual health needs and blood sugar levels.

How long do I need to take Istavel 100mg, and is it safe to stop suddenly?

Type 2 diabetes is usually a long-term condition, so you may need to take Istavel 100mg for many years or indefinitely. Never stop taking this medicine suddenly without talking to your doctor first. Stopping abruptly can cause your blood sugar to rise dangerously. Your doctor will advise you on when to stop or change your treatment if circumstances change.

How does Istavel 100mg compare to Bigomet 500mg (metformin), and when would a doctor choose one over the other?

Istavel 100mg and Bigomet 500 (metformin) both treat type 2 diabetes but work differently. Metformin reduces sugar production in the liver and improves insulin sensitivity. Istavel helps your pancreas release more insulin when needed. Doctors often prescribe them together for better blood sugar control. Your doctor chooses based on your kidney function, stomach tolerance, and how well your blood sugar responds to each medicine.

What should I tell my doctor or pharmacist before I start taking Istavel 100mg?

Tell your healthcare team about all medications you currently take, including over-the-counter medicines and supplements. Mention any allergies, especially to sitagliptin or similar diabetes drugs. Report kidney or liver problems, heart disease, or previous pancreas inflammation. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Share your medical history completely so your doctor can ensure Istavel is safe for you.

Copyright © 2026 AllDayChemist. All rights reserved.