| SKU | 2730 |
|---|---|
| Generic For | Motegrity |
| Active Ingredient | Prucalopride |
| Manufacturer | Sun Pharma, India |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 1.43 | US$ 43.00 | |||
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| 60 Tablet/s | US$ 1.33 | US$ 80.007%US$ 86.00 | |||
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| 100 Tablet/s | US$ 1.20 | US$ 120.0016%US$ 143.00 | |||
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Pruease 2 mg
Pruease 2 mg is a prescription medicine that increases rhythmic movements of the colon in adults with chronic idiopathic constipation (CIC). Idiopathic is when the cause of the constipation is not known. Symptoms of the condition include hard and infrequent stools and incomplete bowel movements. Pruease contains the active ingredient Prucalopride, which is categorized under the class of medications known as gut motility-enhancing medicines. These medicines function on the muscle wall of the gut, which helps to restore the normal functioning of the bowel. They help to relieve the infrequency of bowel movements.
Warning and precautions with Prucalopride tablet
Pruease 2 mg is contraindicated in patients with hypersensitivity to the active ingredient or any other components in the medicine. It should not be given to patients with renal insufficiency requiring dialysis. Pruease is not meant for patients with intestinal obstruction due to structural or functional disease of the gut wall, severe inflammatory issues of the intestinal tract, such as ulcerative colitis, and Crohn’s disease.
‒ There is limited information on the safety and effectiveness of Prucalopride in those who are suffering from severe and unstable concomitant disease (cardiovascular disease, lung disease, neurological or psychiatric disorders, AIDS or cancer, and endocrine conditions. Patients suffering from these conditions should exercise caution when they also have a history of arrhythmias or ischemic cardiovascular disorder.
‒ In those with severe diarrhea, the effectiveness of birth control pills may be reduced, and the use of an additional birth control technique is recommended to prevent possible failure of oral birth control.
‒ The medicine contains lactose. Patients who have hereditary problems of galactose intolerance and glucose-galactose malabsorption should avoid taking this medicine.
‒ The medicine is not recommended during pregnancy and in women of reproductive potential who are not using birth control.
‒ There is no human data on women who actively breastfed while taking Pruease. A decision should be made whether to discontinue treatment or breastfeeding, considering the benefit of breastfeeding for the child and the benefit of therapy for the woman.
‒ Pruease should not be used in children and adolescents younger than 18 years of age.
Side effects of Prucalopride tablet
Like any other pharmaceutical agent, this medicine can cause unwanted effects, although not everybody who uses it gets it. Usually, the side effects occur during the initial days of the treatment and usually resolve within a few days with continued treatment. Common side effects of the medicine include diarrhea, headache, abdominal pain, feeling sick, vomiting, windiness, tiredness, abnormal bowel sounds, disturbed digestion, dizziness, and reduced appetite. Tell your healthcare provider if any of these bothers or becomes troublesome. Uncommon side effects reported with the use of Pruease are rectal bleeding, tremors, fever, an increase in the frequency of passing urine, a pounding heart, and feeling unwell. Seek immediate medical help if a pounding heart occurs.
Usage instructions of Prucalopride tablet
The usual recommended dose for adults is 2 mg once a day before or after consuming food. Exceeding the daily dose is not expected to increase effectiveness. If the daily dose is not effective after four weeks of regular consumption, the patient should be reevaluated and the benefit of continuing therapy reconsidered. The effectiveness of Prucalopride has been established in clinical trials for up to three months. Effectiveness beyond three months in clinical trials has not been evaluated. When used for a longer duration, the benefits should be reassessed at regular intervals.
‒ For people over 65 years old: Begin with 1 mg once a day; if necessary, as per the condition, the dose can be increased to 2 mg once a day.
‒ Patients with kidney impairment: The dose for patients with severe kidney problems is 1 mg once a day. However, no dose adjustment is needed for patients dealing with mild to moderate renal insufficiency.
‒ Patients with liver impairment: The treatment should be started with a reduced dose of 1 mg a day, which may be increased to 2 mg if required to improve effectiveness and if the 1 mg dose is well tolerated. There is no need for dose adjustment for patients with mild to moderate liver problems.
‒ If you discontinue treatment, your symptoms may recur.
‒ Tell your healthcare professional about all medicines you take, including any medicine that you take with a prescription or without a prescription (vitamins, minerals, and natural supplements.
‒ Erythromycin, ketoconazole, digoxin, verapamil, quinidine, atropine-like substances, and cyclosporine are medicines that may interact with Prucalopride.
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