Available Dosages
| SKU: | 671 |
|---|---|
| Generic For: | Toprol XL |
| Active Ingredient: | Metoprolol Succinate |
| Manufacturer: | Cipla, India |
Buy Metolar XR 100mg (Metoprolol Succinate) Online
Metolar XR 100 mg is used in the treatment of high blood pressure. The active ingredient of the drug is Metoprolol Succinate, which is a beta-blocker is mainly prescribed to treat hypertension. The medicine works by affecting the heart and circulation of blood flow through arteries and veins and thereby reducing high blood pressure. Metoprolol is categorized under the drug class known as beta-blockers. It is believed to work by blocking the effects of some chemicals inside the heart and blood vessels. The medicine slows down your heart rate and allows your heart to beat with less force which lowers the blood pressure. This helps in reducing the risk of having heart complications such as a heart attack, kidney problems, kidney problems, and other heart problems.
Before taking Metolar XR 100 mg, let your doctor know if you have complications associated with the liver. The hypertensive agent may not be suitable for some people who have a slow heart rate, low blood pressure, severe circulation problems, and heart failure. Pregnant and breastfeeding mothers should consult their doctor before taking Metoprolol succinate. You must discuss with your doctor to find out whether you are a suitable candidate for Metolar extended-release tablet. Your doctor will monitor your blood pressure levels regularly. Alcohol consumption may increase the risk of side effects.
Use the Metolar XR 100 mg only for the purpose specified and not for any other purpose. Store the medicine in a cool and dark place away from heat, light, and moisture and away from the reach of children. If you must undergo any surgery, you must tell your doctor that you are taking Metoprolol Succinate as the medicine needs to be stopped in such case for some time. The medicine may affect your reflexes and thinking capacity. Hence you must not indulge in an activity that requires a lot of alertness such as operating machinery, driving and likes. It is best not to consume alcohol when you are taking medicine as it may lead to several side effects.
Take Metolar XR 100 mg as per your doctor’s prescription. The medicine is available in the form of extended-release tablet for oral administration. The medicine is to be taken for the prescribed time provided by your doctor and should not be stopped in between as it may lead to adverse effect in the body. For the correct dose, please consult your doctor. Overdose of the medicine can lead to some series side effects. Some of the side effects of an overdose of medicine include breathlessness, uneven heartbeat, dizziness, bluish colour fingernails, seizure, weakness, or fainting. In case of an overdose of the medicine you must get in touch with your doctor immediately.
What is Metolar XR 100mg used for?
Metolar XR 100mg contains Metoprolol Succinate 100mg in extended-release form. It is used for hypertension, stable angina, heart failure with reduced ejection fraction (HFrEF), and stable symptomatic heart failure. Metoprolol Succinate (succinate salt) is the only beta blocker proven to reduce mortality in heart failure in the MERIT-HF trial. The XR formulation provides once-daily dosing with smooth, consistent beta blockade.
What is the difference between Metoprolol Succinate and Metoprolol Tartrate?
Metoprolol Succinate (in Metolar XR) is an extended-release formulation with a longer, more consistent duration of action — suitable for once-daily dosing. Metoprolol Tartrate (in Metolar) is immediate-release, requiring twice-daily dosing for adequate coverage. Crucially, only Metoprolol Succinate (XR/ER form) has been proven in large RCTs to reduce mortality in heart failure — the MERIT-HF trial used Metoprolol Succinate, not Tartrate. For heart failure, the succinate salt is the required formulation.
What is the recommended dose of Metolar XR 100mg?
For heart failure, the up-titration protocol starts at 12.5mg or 25mg once daily and doubles every two weeks to a target of 200mg once daily. Metolar XR 100mg is an important intermediate step. For hypertension, 100mg once daily is a common maintenance dose. For angina, the dose may be 100–200mg daily. Always follow your cardiologist's prescribed titration schedule — dose changes in heart failure must be gradual.
How should Metolar XR 100mg be taken?
Take Metolar XR 100mg once daily with or immediately after a meal. Food improves bioavailability of Metoprolol Succinate by approximately 40%. Do not crush, chew, or split the tablet — this destroys the extended-release mechanism. Swallow whole with a glass of water. Take at the same time each day. If a dose is missed on the same day, take it as soon as you remember; if the following day, skip and resume the normal schedule.
Is Metolar XR 100mg safe in patients with type 2 diabetes?
Metoprolol Succinate is a cardioselective beta-1 blocker and is safer than non-selective agents in diabetes. It may mildly impair insulin-induced hypoglycaemia recovery and mask tachycardia as a hypoglycaemia warning sign. However, the cardiovascular benefits of Metoprolol Succinate in diabetic patients with heart failure or hypertension far outweigh these risks. Monitor glucose more carefully when starting or adjusting the dose.
Can Metolar XR 100mg be combined with ACE inhibitors?
Yes. In heart failure with reduced ejection fraction, the combination of an ACE inhibitor (or ARB/ARNI) and Metoprolol Succinate is guideline-mandated therapy — both independently reduce mortality, and the combination provides additive survival benefit. Start both medications at low doses and titrate each one separately. Metolar XR 100mg and a concurrent ACE inhibitor can both be safely up-titrated in parallel under cardiologist guidance.
How does Metolar XR 100mg compare to Toprol-XL 100mg?
Metolar XR 100mg and Toprol-XL 100mg both contain Metoprolol Succinate 100mg in extended-release form. Toprol-XL is the AstraZeneca originator brand used in the MERIT-HF trial. Metolar XR from Cipla is the bioequivalent generic alternative. The mortality benefit demonstrated in MERIT-HF applies to generic Metoprolol Succinate as it contains the same active molecule. AllDayChemist offers Metolar XR at a fraction of Toprol-XL's price.
Is Metolar XR 100mg equivalent to Toprol-XL for heart failure treatment?
Yes. Generic Metoprolol Succinate extended-release (including Metolar XR) is bioequivalent to Toprol-XL. The FDA requires proof of identical drug release profiles and systemic exposure before approving generic XR products. Cardiology guidelines do not distinguish between brand and generic Metoprolol Succinate extended-release for heart failure management. AllDayChemist provides Cipla's Metolar XR — a trusted quality source.
Can I order Metolar XR 100mg from AllDayChemist?
Yes. Metolar XR 100mg is available at AllDayChemist with worldwide shipping to the USA, UK, Australia, and 200+ countries. AllDayChemist has operated since 2002 with direct sourcing from Cipla. Orders ship in discreet, plain packaging with tracking. Free shipping is available on qualifying orders. Visit AllDayChemist.com.
What savings can I expect when buying Metolar XR 100mg at AllDayChemist?
Metolar XR 100mg at AllDayChemist is priced significantly below Toprol-XL or generic Metoprolol Succinate XR at US retail pharmacies. For patients on long-term once-daily heart failure therapy, the cost savings over months and years can be substantial. Since 2002, AllDayChemist has served 200+ countries with free shipping on qualifying orders and discreet delivery for all cardiac medications.
What side effects does Metolar XR 100mg cause?
Common side effects include fatigue, bradycardia, dizziness, cold extremities, and headache. The XR formulation typically causes fewer peak-related side effects (less fatigue or dizziness) than immediate-release Metoprolol at equivalent daily doses. Worsening heart failure can occur transiently during initiation — monitor weight daily. Vivid dreams or insomnia are less common than with Propranolol but more common than with Atenolol due to Metoprolol's partial lipophilicity.
What precautions are needed with Metolar XR 100mg?
Never stop abruptly — sudden withdrawal risks rebound tachycardia, angina, or MI. Taper over one to two weeks. Swallow whole — do not crush or chew. Take with food. Avoid in decompensated heart failure, severe bradycardia, sick sinus syndrome, and significant AV block. Inform your anaesthetist about Metoprolol use before surgery. Diabetics must monitor glucose carefully. Do not combine with verapamil or diltiazem without close cardiac monitoring.
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