Available Dosages
| SKU: | 9 |
|---|---|
| Generic For: | Zovirax |
| Active Ingredient: | Acyclovir |
| Manufacturer: | Cipla, India |
Buy Acivir Cream 10gm (Acyclovir) for Herpes & Chickenpox
Acivir Cream 10gm is a prescription topical antiviral preparation containing Acyclovir 5% (w/w) in a cream base, used for the treatment of herpes simplex virus infections of the skin and mucous membranes — most commonly cold sores (herpes labialis) caused by HSV-1 and cutaneous herpes simplex infections caused by HSV-1 or HSV-2. Acivir Cream delivers targeted antiviral activity directly to infected skin lesions, reducing healing time and relieving the discomfort of active herpetic outbreaks. As a topical formulation, it has minimal systemic absorption, making it well-tolerated and carrying a very low risk of systemic side effects.
What is Acivir Cream 10gm?
Acivir Cream 10gm is a topical antiviral cream containing Acyclovir 5%, formulated for direct application to active herpes simplex lesions on the skin and lips. It is indicated for the treatment of herpes labialis (cold sores) — the most common presentation of orofacial HSV-1 infection — and for other cutaneous herpes simplex infections. The cream formulation penetrates the epidermis and delivers Acyclovir to infected cells in the superficial skin layers. Applied promptly at the first sign of an outbreak (tingling, itching, or burning before lesions appear), Acivir Cream reduces the duration and severity of the outbreak, accelerates healing, and shortens the period of virus shedding. The 10gm tube provides a sufficient quantity for a standard treatment course.
Manufacturer: Acivir Cream is manufactured by Cipla Ltd., one of India’s most trusted pharmaceutical companies and a leading global producer of antiviral formulations, and maintains the highest quality standards for dermatological preparations.
Key Ingredients of Acivir Cream and Their Working Process
The active ingredient, Acyclovir 5%, exerts its antiviral effect within infected skin cells through the same selective mechanism as oral Acyclovir, but is delivered topically. Acyclovir penetrates the stratum corneum and reaches epidermal cells infected with herpes simplex virus. Inside infected cells, viral thymidine kinase phosphorylates Acyclovir to its active monophosphate — a step that does not occur in uninfected human cells, conferring selectivity. Further phosphorylation by cellular enzymes produces Acyclovir triphosphate, which inhibits viral DNA polymerase and terminates viral DNA replication. By halting viral replication within infected epidermal keratinocytes, topical Acyclovir reduces virus titre in the lesion, shortens the period of viral shedding, accelerates lesion healing, and alleviates local symptoms. Systemic absorption from topical application is minimal, limiting any risk of systemic antiviral effects or side effects.
Clinical Uses of Topical Acyclovir 5%
Acivir Cream is indicated for the topical treatment of initial and recurrent herpes labialis (cold sores) in immunocompetent adults, and for the treatment of cutaneous herpes simplex infections. The primary benefit is a reduction in healing time by approximately one to two days when treatment is started at the prodromal stage — the tingling and itching sensation before visible lesions appear. It reduces viral shedding from active lesions, decreasing transmission risk. It is not indicated for genital herpes (where oral antiviral therapy is the standard of care), herpes in the eye (ophthalmic Acyclovir preparations are used), or mucosal herpes infections of the mouth or genitalia, where deeper tissue penetration is needed.
Comparing Acivir Cream and Zovirax Cream: Brand vs Generic Differences
Acivir Cream 5% is a generic equivalent of Zovirax Cold Sore Cream (GSK), the branded reference topical Acyclovir product. Both contain Acyclovir 5% in a cream vehicle and are bioequivalent in terms of drug delivery to skin. Zovirax Cold Sore Cream is widely available over the counter in many markets at a premium price. Acivir Cream from Cipla provides the same antiviral topical effect at significantly lower cost, making it an economical option for patients who experience recurrent cold sore outbreaks.
Related strengths and products: Acivir 400mg DT (oral Acyclovir 400mg dispersible tablets) is available for patients with frequent or severe cold sore recurrences who require oral antiviral suppressive therapy alongside topical treatment. Acivir 800mg DT is available for herpes zoster or chickenpox requiring high-dose oral Acyclovir. For patients with recurrent extensive cold sores or immunocompromised individuals, systemic oral Acyclovir is generally more effective and may be preferred over topical therapy alone.
Key Benefits of Acivir Cream 10gm
Acivir Cream 10gm delivers convenient, targeted antiviral activity directly to cold sore lesions without the need for oral medication or systemic drug exposure. When started early — at the prodromal tingling stage — it reduces outbreak severity and accelerates healing. The cream vehicle moisturises and soothes irritated skin while delivering the antiviral agent. The 10gm tube provides ample product for a standard treatment course, with additional cream available for subsequent outbreaks. Cipla’s pharmaceutical manufacturing quality ensures consistent Acyclovir concentration throughout the product.
Usage warnings and precautionary advice for using Acyclovir Cream
Acivir Cream is for external use only — avoid contact with eyes, mouth, and mucous membranes. It is not effective against herpes infections of the mouth, genital area, or eyes. Do not use on normal or unaffected skin. Patients with a known hypersensitivity to Acyclovir, Valacyclovir, or any excipient in the cream should not use this product. Topical Acyclovir cream is not a cure for herpes simplex infection — the virus remains latent in nerve ganglia and will cause future outbreaks. Do not use in or around the eyes — ophthalmic formulations are required for herpes keratitis. Use in pregnancy should be limited to when clearly needed — systemic absorption is minimal, but should be considered. The cream has not been shown to prevent transmission of herpes to sexual partners.
Side effects of Acyclovir Cream 5%
Most patients tolerate Acivir Cream well. Mild transient stinging, burning, or tingling at the application site is the most commonly reported reaction, particularly when applied to broken or vesicular skin. Dryness, flaking, or superficial peeling at the application site may occur with repeated application. Contact dermatitis and skin hypersensitivity reactions — redness, itching, rash — have been reported in a small number of patients and require discontinuation of the cream. Acyclovir allergy manifesting as urticaria or angioedema is rare but requires immediate medical attention. Systemic side effects are not expected with topical application, as systemic absorption is negligible.
Benefits of Buying Acivir Cream Online
AllDayChemist provides affordable, convenient access to authentic Acivir Cream 10gm at prices well below branded Zovirax cream alternatives. For patients who experience recurrent cold sores and maintain a tube of Acivir Cream for early-treatment use, AllDayChemist’s home delivery model ensures a consistent supply without requiring a pharmacy visit. Access a wide range of herpes and HIV medicines and compare pricing to save the most on your medicines.
Proper dosage and usage guide of Acyclovir Cream 5%
Apply a small amount of Acivir Cream to the affected area five times daily, approximately every four hours, for 5 days. Begin application as early as possible — ideally at the very first sign of a cold sore (tingling, itching, or redness) before vesicles form. Wash and dry hands thoroughly before and after application. Use a clean cotton bud or fingertip to apply a thin layer of cream to the lesion and the surrounding skin. Do not apply inside the mouth, eyes, or on mucous membranes. Do not cover with bandages or occlusive dressings. Avoid applying to broken skin beyond the lesion borders. Wash your hands immediately after application to prevent the virus from spreading to other sites. If no improvement is seen after 10 days, consult a healthcare provider. Store at room temperature (below 25°C) away from moisture and direct sunlight.
What is Acivir Cream 10gm prescribed for, and which patients benefit most from it?
Acivir Cream is used to treat infections caused by the herpes simplex virus. This includes cold sores on the lips and genital herpes. The cream works best when applied early, as soon as you notice tingling or the first signs of a sore appearing. It is most helpful for people who get frequent outbreaks or want to reduce healing time and pain during an active infection.
How does Acyclovir work?
Acyclovir is an antiviral medicine that stops the herpes virus from multiplying and spreading. It does this by blocking the virus's ability to copy itself and create new infection. The cream works directly on your skin where you apply it, helping your immune system clear the infection faster and reducing pain, itching, and the time it takes for sores to heal.
How should I prepare my skin before applying this cream?
Wash the area gently with soap and cool water, then pat it completely dry with a clean towel. Do not rub hard or scrub, as this can irritate the sore further. Make sure your hands are clean before touching the area. If the sore is crusty or has fluid, gently clean away any loose material. Apply the cream to clean, dry skin for best results.
How long before I see results, and what should I realistically expect?
Many people notice improvement within two to three days of starting treatment. You may see reduced pain, itching, or redness. However, complete healing usually takes seven to ten days depending on how severe the outbreak is. Starting the cream very early, as soon as you feel tingling, gives the best chance of faster healing and less severe sores.
Can I apply sunscreen or makeup over this cream?
You can apply sunscreen over Acivir Cream once it has fully absorbed into your skin, usually after a few minutes. Avoid putting makeup directly over active sores as it can trap moisture and slow healing. If you must use makeup, wait until the sore is less red and weeping. Always let the cream dry completely before adding any other products on top.
Is this cream safe near my eyes, lips, or on delicate skin?
Acivir Cream is safe on the lips and can be used for cold sores in that area. However, avoid getting it directly into your eyes as it may cause irritation. For skin around the eyes, use caution and apply only to the infected area, not near the eye itself. If you accidentally get cream in your eye, rinse thoroughly with water and contact your pharmacist or doctor.
What are the most important safety warnings I need to know before using Acivir Cream 10gm?
Do not use this cream if you are allergic to acyclovir or any other ingredient in the product. Avoid contact with eyes, nose, and mouth. Do not apply to areas with broken skin unless directed by your doctor. Pregnant or breastfeeding women should consult their doctor before use. Keep the cream away from children and pets. Wash hands after applying unless treating your hands.
How does Acivir Cream 10gm compare to the brand Zovirax and other treatments for Anti Viral?
Acivir Cream contains the same active ingredient, acyclovir, as the original brand- Zovirax. Both work equally well for treating herpes infections. Acivir is a more affordable option without sacrificing quality or effectiveness. Other antiviral creams may use different ingredients, but acyclovir remains the most proven and widely used treatment for herpes sores, making this cream a reliable choice.
How long do I need to use Acivir Cream 10gm, and is it safe to stop the usage suddenly?
Most people use Acivir Cream for five to ten days during an active outbreak. You can safely stop using it once the sore has healed or as directed by your doctor. There is no risk from stopping suddenly since this is a topical cream, not a medicine taken by mouth. Do not continue using it longer than two weeks without speaking to your doctor or pharmacist.
What should I tell my dermatologist before I start using Acivir Cream 10gm?
Tell your doctor if you have a weak immune system, kidney problems, or if you are pregnant or breastfeeding. Mention any allergies to acyclovir or similar medicines. Let them know if you are using other creams or medicines on the same area of skin. If you have severe or frequent outbreaks, your doctor may suggest additional preventive treatment. Always inform them about any skin conditions that might affect treatment safety.
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