Available Dosages
| SKU: | 33 |
|---|---|
| Generic For: | Norvasc |
| Active Ingredient: | Amlodipine Besilate |
| Manufacturer: | Cipla, India |
Buy Amlopres 10 mg (Amlodipine Besilate) Online
High blood pressure and angina are among the most prevalent cardiovascular conditions globally, and effective long-term management is critical to preventing heart attacks, strokes, and other life-threatening events. Amlopres 10mg is a clinically proven calcium channel blocker that delivers powerful, sustained blood pressure control and relieves the chest pain of angina. Containing Amlodipine Besylate — one of the world's most prescribed antihypertensive agents — Amlopres 10mg relaxes and widens blood vessels, reducing the workload on the heart and improving blood flow. Trusted by cardiologists for decades and recommended in major cardiovascular treatment guidelines, Amlopres 10mg is a foundation of long-term heart health management.
What is Amlopres 10mg?
Amlopres 10mg is an oral tablet containing Amlodipine Besylate equivalent to Amlodipine 10mg as its active ingredient. Amlodipine belongs to the dihydropyridine class of calcium channel blockers (CCBs). It works by blocking L-type calcium channels in vascular smooth muscle and cardiac muscle cells, causing vasodilation (widening of blood vessels) and reducing the force of the heart's contractions. Amlopres 10mg represents the higher end of the standard dosing range and is typically prescribed when lower doses (2.5mg or 5mg) have not achieved adequate blood pressure or angina control.
Manufacturer: Amlopres 10mg is manufactured by Cipla Ltd., one of India's most respected and globally operating pharmaceutical companies with a longstanding reputation for producing high-quality cardiovascular medications.
Key Ingredients of Amlopres 10mg and Their Working Process
Amlodipine Besylate (equivalent to Amlodipine 10mg) is a long-acting dihydropyridine calcium channel blocker. Its mechanism of action involves:
- Calcium channel blockade: Selectively inhibits the entry of calcium ions through L-type voltage-gated calcium channels in the smooth muscle of arterial walls and cardiac tissue
- Peripheral vasodilation: Relaxation of arterial smooth muscle reduces peripheral vascular resistance (afterload), lowering blood pressure
- Coronary vasodilation: Dilates coronary arteries, increasing oxygen supply to the heart muscle — directly beneficial in angina
- Reduced cardiac workload: Lower peripheral resistance means the heart pumps against less resistance, reducing myocardial oxygen demand
- No reflex tachycardia: Unlike some other vasodilators, Amlodipine's gradual onset minimises reflex sympathetic activation that would increase heart rate
- 24-hour duration: Amlodipine's long plasma half-life (~30–50 hours) enables once-daily dosing with smooth, sustained blood pressure control across the full 24 hours
Clinical Uses of Amlodipine
Amlodipine is indicated for:
- Hypertension (High Blood Pressure): Used as monotherapy or in combination with ACE inhibitors (Lisinopril), ARBs, beta-blockers, or diuretics (Spironolactone) for comprehensive blood pressure management
- Stable Angina Pectoris: Reduces the frequency and severity of angina episodes by improving coronary blood flow and reducing myocardial oxygen demand
- Vasospastic (Prinzmetal's) Angina: Highly effective due to its direct coronary vasodilating action
- Coronary Artery Disease (CAD): Reduces cardiovascular events in patients with documented CAD (CAMELOT trial evidence)
- Hypertension in Diabetes: Preferred CCB in diabetic patients with hypertension — does not adversely affect insulin sensitivity or glucose metabolism
The difference between the brand Norvasc and the generic Amlopres
Norvasc and Amlopres both contain the same active ingredient, Amlodipine, which is commonly prescribed to treat high blood pressure and chest pain (angina). The main difference is that Norvasc is the original branded version developed by Pfizer, while Amlopres is a generic alternative manufactured by other pharmaceutical companies. Both medicines work similarly by relaxing blood vessels and improving blood flow. Generic versions like Amlopres are usually more affordable because they do not carry brand-development costs. Although the active ingredient, dosage, safety, and effectiveness are considered equivalent, inactive ingredients, such as color, fillers, or coating, may differ slightly. Doctors may prescribe either option depending on patient preference, availability, and cost considerations.
Related strengths and products: AllDayChemist offers the complete Amlopres range for tailored cardiovascular management — Amlopres 2.5mg for initiation, Amlopres 5mg for standard blood pressure control, and Amlopres 10mg for maximal antihypertensive effect. For combination hypertension therapy, complement with Lipril 10mg (Lisinopril ACE inhibitor) or Aldactone 25mg (Spironolactone) as directed by your physician.
Key Benefits of Amlopres 10mg
- Potent, once-daily blood pressure control — 24-hour smooth antihypertensive effect with a single tablet
- Dual cardiovascular benefit — treats both hypertension and angina simultaneously.
- Well-established safety record — one of the world's most prescribed antihypertensives for over 30 years
- Minimal drug interactions — compatible with most other antihypertensives and cardiac medications
- No metabolic side effects — does not affect blood glucose, lipid profiles, or renal function adversely.
- Safe in elderly patients and those with renal impairment (no dose adjustment required for renal disease)
- Safe in asthma/COPD patients — unlike beta-blockers, CCBs do not cause bronchospasm.
- Reduced cardiovascular event risk — evidence supports a reduction in stroke, MI, and cardiovascular mortality.
Usage warnings and precautionary advice for using Amlodipine
- Peripheral oedema: Ankle swelling (oedema) is the most common side effect at higher doses — elevating feet when resting can help; inform your doctor if swelling is significant
- Severe aortic stenosis: Use with caution — vasodilation can compromise perfusion in critical aortic stenosis
- Liver impairment: Amlodipine is metabolised by the liver; dose reduction may be required in severe hepatic impairment — consult your physician
- Hypotension: Excessive blood pressure lowering (particularly in the first week) — rise slowly from sitting or lying positions
- Drug interactions: Simvastatin dose should not exceed 20mg daily when taken with Amlodipine. CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase Amlodipine levels; CYP3A4 inducers (e.g., rifampicin, St. John's Wort) may decrease its efficacy
- Pregnancy: Use only if clearly needed and under physician supervision; weigh risk vs. benefit
- Breastfeeding: Not recommended — Amlodipine may pass into breast milk
- Elderly patients: Start with 5mg if transitioning from lower doses; monitor for hypotension and oedema
- Keep out of reach of children; store below 30°C, away from moisture
Side effects of Amlodipine
Amlopres 10mg is generally well tolerated. Common and less common side effects include:
- Common (more likely at 10mg): Peripheral oedema (ankle/foot swelling) — the most frequent side effect; flushing (feeling of warmth, redness in face); headache; dizziness; palpitations
- Less common: Fatigue, nausea, abdominal pain, skin rash, pruritus (itching)
- Rare: Severe hypotension, chest pain (particularly at initiation or dose increase), mood changes, visual disturbances, Stevens-Johnson syndrome (very rare skin reaction)
Peripheral oedema is dose-dependent and is more common at 10mg than at lower doses. If swelling is uncomfortable or cosmetically concerning, discuss alternative dosing strategies with your physician.
Benefits of Buying Amlopres 10mg Online
Managing a chronic condition like hypertension requires consistent, reliable access to your medication — and AllDayChemist makes this easier and more affordable. Purchasing Amlopres 10mg through AllDayChemist gives you access to genuine Cipla-manufactured tablets at competitive prices, with the convenience of home delivery that fits your lifestyle. The website's secure ordering system, discreet packaging, and trusted international delivery network ensure your cardiovascular medications reach you reliably. With a comprehensive range of heart health products available in one place, AllDayChemist is your dependable partner in long-term cardiovascular care.
Proper dosage and usage guide of Amlodipine
- Take Amlopres 10mg orally once daily, at the same time each day, with or without food
- Swallow the tablet whole with a glass of water
- Do not crush or chew the tablet
- Blood pressure reduction begins within hours of the first dose, but maximum antihypertensive benefit is typically achieved after 7–14 days of regular use
- If a dose is missed, take it as soon as you remember — unless it is almost time for the next dose, in which case skip the missed dose and continue your regular schedule. Never double up
- Do not stop taking Amlopres suddenly without your doctor's advice — abrupt discontinuation may cause rebound hypertension or worsening of angina
- Regularly monitor your blood pressure at home or at your physician's clinic to track treatment effectiveness
- Avoid grapefruit and grapefruit juice during Amlodipine therapy — grapefruit can increase Amlodipine blood levels and intensify side effects
What is Amlopres 10mg used for?
Amlopres 10mg (Amlodipine) is used to treat hypertension and angina pectoris (chest pain). It lowers blood pressure and improves blood supply to the heart muscle.
How does Amlodipine in Amlopres 10mg work?
Amlodipine is a calcium channel blocker. It relaxes the smooth muscle in blood vessel walls, reducing vascular resistance and lowering blood pressure.
What is the difference between Amlopres 5mg and 10mg?
The 10mg dose provides stronger blood pressure and angina control. It is used when the 5mg dose is insufficient. Dose escalation should always be guided by your doctor.
Does Amlopres 10mg cause ankle swelling?
Yes. Peripheral oedema (ankle and foot swelling) is a common side effect of Amlodipine and results from the vasodilatory effect of the drug. Inform your doctor if this occurs.
Can I stop taking Amlopres 10mg if I feel fine?
Do not stop without medical advice. Hypertension usually has no symptoms. Stopping suddenly could allow blood pressure to rise rapidly, increasing the risk of stroke or heart attack.
Is Amlopres 10mg safe for elderly patients?
Amlodipine is frequently used in elderly patients and is generally well tolerated. However, elderly patients may be more susceptible to hypotension; close monitoring is important.
Can I buy Amlopres 10mg from AllDayChemist at a lower price?
Yes, Amlopres 10mg is available on AllDayChemist at highly competitive prices. The platform offers genuine Amlodipine tablets at significant discounts compared to local pharmacies, with convenient worldwide delivery.
What foods should I avoid while taking Amlopres 10mg?
Grapefruit and grapefruit juice should be avoided, as they can inhibit Amlodipine metabolism, increasing drug levels in the blood and potentially causing excessive blood pressure lowering.
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Login
Sign Up
Leading Online Pharmacy
100% Genuine
Products
& OTC Products
Forgot Password ?