Supatret Gel .04% (20 gm)
Out Of Stock
| SKU: | 1146 |
|---|---|
| Generic For: | Retin A Micro |
| Active Ingredient: | Tretinoin Gel Microsphere |
| Manufacturer: | Sun Pharma, India |
Buy Supatret Gel .04% (20 gm) (Tretinoin Gel Microsphere) for Acne & Wrinkles
Supatret Gel 0.04% is a prescription topical retinoid formulation containing Tretinoin 0.04% in a gel base, used to treat acne vulgaris. It is a well-established dermatological product that promotes skin cell turnover, unclogs pores, and prevents the formation of new comedones and inflammatory acne lesions. As a retinoid — a vitamin A derivative — Tretinoin is one of the most extensively studied and clinically validated acne treatments available, with decades of evidence supporting its efficacy as both a standalone therapy and in combination with antibacterial acne agents.
What is Supatret 0.04% Gel?
Supatret 0.04% Gel is a topical prescription formulation containing Tretinoin 0.04% in a non-greasy gel vehicle. It is indicated for the topical treatment of acne vulgaris, including both comedonal (blackheads and whiteheads) and inflammatory (papules and pustules) acne, particularly on the face. The 0.04% concentration is a mid-range strength within the Tretinoin range (0.01% to 0.1%)—potent enough to deliver significant clinical benefit while tolerable for most skin types, including sensitive skin. The gel vehicle is preferred over cream formulations in oily or acne-prone skin as it is lighter, less comedogenic, and better absorbed. Supatret Gel is applied once daily at night and is typically part of a sustained treatment programme lasting at least 12 weeks.
Manufacturer: Supatret 0.04% Gel is manufactured by Sun Pharma, India’s largest pharmaceutical company and a globally respected name in dermatology, with an extensive portfolio of prescription acne and skin care products.
Key Ingredients of Supatret Gel and Their Working Process
The active ingredient is Tretinoin (all-trans retinoic acid), a naturally occurring metabolite of vitamin A and the most biologically active retinoid for topical use. Tretinoin binds to nuclear retinoic acid receptors (RARs) in skin keratinocytes, altering gene expression to regulate cell proliferation and differentiation. In acne pathogenesis, abnormal follicular hyperkeratinisation causes cells to clump together within the follicle, blocking the pore and creating the environment for comedone formation and Cutibacterium acnes (formerly Propionibacterium acnes) colonisation. Tretinoin normalises follicular epithelial differentiation — cells shed more loosely and regularly, preventing pore blockage. It also reduces the cohesiveness of follicular epithelial cells, dissolving existing comedones, and has anti-inflammatory properties that contribute to the resolution of papules and pustules. Additionally, Tretinoin at higher concentrations stimulates collagen synthesis and has anti-ageing effects, improving fine lines and photoaged skin.
Clinical Uses of Tretinoin 0.04% Gel
Tretinoin 0.04% gel is clinically indicated for the treatment of mild to moderate acne vulgaris involving comedonal and inflammatory lesions, particularly on the face, and to a lesser extent on the chest and back. It is most effective for comedonal acne (blackheads and whiteheads) but also reduces inflammatory lesions when used consistently. It is frequently combined with a topical antibacterial agent — such as Clindamycin phosphate (Acnesol Gel 1%) — for inflammatory acne, and this combination addresses both the comedonal and the bacterially-driven components simultaneously. Tretinoin is also used off-label for photoageing (fine lines, uneven pigmentation), melasma, and post-acne hyperpigmentation as part of a dermatologist-supervised regimen.
Comparing Supatret Gel and Retin-A: Brand vs Generic Differences
Supatret 0.04% Gel is a generic equivalent of Retin-A (Janssen/Ortho Dermatologics) in the 0.04% or 0.05% gel range. Both contain Tretinoin as the active ingredient at equivalent concentrations and deliver the same mechanism of action and clinical outcomes for acne treatment. Branded Retin-A commands a premium price in Western markets, whereas Supatret from Sun Pharma offers the same dermatological benefits at a significantly lower cost.
Related strengths and products: Supatret Gel is also available as Supatret 0.025% Gel for patients with more sensitive skin or those initiating Tretinoin therapy who require a gentler starting strength. For combination acne therapy, Acnesol Gel 1% (Clindamycin Phosphate 1%) can be used in the morning while Supatret is applied at night — addressing bacterial and comedonal causes simultaneously. Adaferin Gel 0.1% (Adapalene 0.1%) is an alternative third-generation retinoid with a better tolerability profile for patients who cannot tolerate Tretinoin.
Key Benefits of Supatret 0.04% Gel
Supatret 0.04% Gel addresses acne at its root — abnormal pore clogging — rather than simply reducing surface bacteria. Its comedolytic action clears existing comedones while preventing new ones, providing lasting improvement rather than temporary suppression. The gel vehicle is suitable for oily, combination, and acne-prone skin without causing additional greasiness. The 0.04% concentration delivers meaningful clinical efficacy with acceptable tolerability for most patients. As a Sun Pharma formulation, it offers pharmaceutical-grade Tretinoin at a fraction of the cost of branded alternatives.
Usage warnings and precautionary advice for using Tretinoin
Supatret 0.04% Gel is contraindicated during pregnancy — Tretinoin is teratogenic when absorbed systemically, and topical use should be avoided during pregnancy as a precaution. Women of childbearing age should use effective contraception during treatment. Avoid prolonged sun exposure—use daily sunscreen and protective clothing. Tretinoin is not recommended for use with other retinoids, strong chemical peels, or extensive exfoliation, as cumulative irritation may lead to severe disruption of the skin barrier. Avoid waxing, hair removal creams, or dermabrasion on Tretinoin-treated skin. Inform your dermatologist of all other topical agents you are using. Patients with eczema, rosacea, or perioral dermatitis should use Tretinoin with caution, as it can worsen these conditions.
Side effects of Tretinoin 0.04% Gel
Skin irritation — redness, peeling, flaking, dryness, and a sensation of warmth or stinging — is the most commonly reported side effect, particularly during the first four to eight weeks of use. This is largely expected and represents the retinoid adaptation phase; it usually subsides with continued use and can be minimised by using a gentle non-comedogenic moisturiser. Increased photosensitivity is consistent and requires strict daily sunscreen use. Temporary initial acne worsening (purging) occurs in many patients as existing microcomedones are accelerated to the surface — this resolves within 4 to 6 weeks and should not prompt discontinuation. Hyperpigmentation may occur at the site of previous acne lesions, particularly in darker skin types — this is temporary.
Benefits of Buying Supatret 0.04% Gel Online
AllDayChemist offers dermatology patients authentic Supatret 0.04% Gel at prices significantly lower than those of branded Tretinoin products. For a medication requiring consistent, long-term use for sustained acne control, the cost savings from AllDayChemist are meaningful. Discreet packaging and worldwide delivery make it convenient for patients to maintain their dermatological treatment plan without interruption. The simple prescription upload and secure ordering process ensures a smooth experience.
Proper dosage and usage guide of Tretinoin 0.04% Gel
Apply a small amount of Supatret 0.04% Gel to the affected area once daily, in the evening, after washing and gently drying the face. Use a pea-sized amount for the entire face — applying too much does not improve efficacy and significantly increases irritation. Avoid the eyes, lips, nasal folds, and mucous membranes. Allow the skin to dry for 20 to 30 minutes after washing before applying Tretinoin — wet skin dramatically increases penetration and irritation. A daily broad-spectrum SPF 30 or higher sunscreen must be applied every morning without exception, as Tretinoin significantly increases photosensitivity. Do not use alongside harsh exfoliants, benzoyl peroxide (unless specifically directed), or other irritating topical agents in the initial phase. Initial worsening — a purging phase — is common during the first 4 to 6 weeks as existing microcomedones are brought to the surface. Visible improvement typically begins after 8 to 12 weeks of consistent use.
What is Supatret 0.04% Gel used for?
Supatret 0.04% Gel (Tretinoin) is a topical retinoid used to treat acne vulgaris, reduce fine lines and wrinkles, and improve skin texture and tone.
How does Tretinoin in Supatret Gel work?
Tretinoin accelerates skin cell turnover, unclogs pores, reduces comedones, and stimulates collagen production. It treats acne and gradually improves signs of photoageing.
How should Supatret 0.04% Gel be applied?
Apply a pea-sized amount to clean, dry skin at night. Avoid the eye area, lips, and nostrils. Begin with alternate nights to build tolerance, then progress to nightly use.
Why does my skin get worse after starting Supatret Gel?
Initial purging is common with Tretinoin as it accelerates the surfacing of existing clogged pores. This typically resolves within 4 to 8 weeks as skin adapts.
Should I use sunscreen while using Supatret 0.04% Gel?
Yes. Tretinoin increases skin photosensitivity. Apply a broad-spectrum SPF 30+ sunscreen every morning and avoid prolonged sun exposure throughout treatment.
Can Supatret 0.04% Gel be used during pregnancy?
No. Tretinoin is contraindicated in pregnancy. Women of childbearing age should use reliable contraception while using topical retinoids and consult a doctor before starting treatment.
Where can I buy Supatret 0.04% Gel online?
AllDayChemist offers Supatret 0.04% Gel at affordable prices with convenient home delivery. Upload your dermatologist's prescription to complete your secure online order.
How long does it take to see results with Supatret Gel?
Most users notice improvement in acne within 8 to 12 weeks. Anti-ageing effects such as smoother texture and reduced fine lines may take 3 to 6 months of consistent use.
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