Available Dosages
| SKU: | 82 |
|---|---|
| Generic For: | Azelex Cream |
| Active Ingredient: | Azelaic Acid |
| Manufacturer: | Micro Lab, India |
Buy Aziderm Cream 20 % (15gm) (Azelaic Acid) for Acne & Rosacea
Aziderm Cream 20% is a prescription-strength topical formulation containing Azelaic Acid 20%, used in the treatment of moderate to severe acne vulgaris, rosacea with inflammatory lesions, and persistent post-inflammatory hyperpigmentation. Manufactured by Glenmark Pharmaceuticals, it delivers the maximum approved topical concentration of Azelaic Acid. It is recommended when lower-strength formulations have provided insufficient results or when the clinical presentation warrants more aggressive topical management. With a well-established mechanism of action spanning antibacterial, comedolytic, and skin-tone-normalizing effects, Aziderm Cream 20% is a cornerstone of medical-grade acne and pigmentation therapy.
What is Aziderm Cream 20%?
Aziderm Cream 20% is a topical cream containing Azelaic Acid 20% per gram of cream. It is the higher-strength variant in the Aziderm range and is indicated for patients requiring more substantial Azelaic Acid exposure than the 10% formulation provides. At this concentration, the antibacterial, anti-comedonal, and tyrosinase-inhibiting properties of Azelaic Acid are maximized, making it one of the most evidence-backed topical treatments available for adult acne, papulopustular rosacea, and melasma. The cream base is suitable for normal to dry skin types; patients with oily skin may prefer a gel formulation if available. The 15g tube delivers a clinically appropriate quantity for facial application over a treatment course of several weeks.
Manufacturer: Aziderm Cream 20% is manufactured by Glenmark Pharmaceuticals Ltd., a globally respected Indian pharmaceutical company with a leading dermatology division, internationally accredited manufacturing facilities, and a broad portfolio of evidence-based skin care products distributed across multiple regulated markets.
Key Ingredients of Aziderm Cream 20% and Their Working Process
Azelaic Acid 20% works through several interconnected mechanisms that address the root causes of acne and skin discolouration with a depth and breadth unmatched by single-mechanism topical agents. At the 20% concentration, its antibacterial activity against Cutibacterium acnes (formerly Propionibacterium acnes) is substantially stronger than at lower concentrations, achieved by inhibiting bacterial protein synthesis through interference with the thioredoxin reductase enzyme system—a pathway entirely distinct from conventional antibiotics, meaning resistance does not develop. This makes Aziderm 20% particularly valuable in patients who have developed resistance to topical Clindamycin or Erythromycin following prolonged antibiotic use.
The comedolytic action of Azelaic Acid at 20% is driven by normalization of the hyperkeratosis in the follicular canal — the process by which excess dead skin cells accumulate inside pores and combine with sebum to form comedones. By regulating keratinocyte differentiation and reducing the excessive stickiness of desquamating cells within the follicle, Azelaic Acid 20% unblocks existing comedones and prevents new ones from forming. Its potent tyrosinase inhibition at this concentration delivers more aggressive lightening of hyperpigmented areas — including melasma, post-inflammatory hyperpigmentation, and acne-related dark marks — by reducing melanin synthesis in overactive melanocytes. Importantly, Azelaic Acid selectively targets abnormally active melanocytes without depigmenting normally pigmented skin, making it safer for use on skin of colour than hydroquinone-based preparations.
Clinical Uses of Azelaic Acid 20%
Azelaic Acid 20% is clinically indicated as a first-line treatment for moderate acne vulgaris in adults and adolescents, and as a second-line option in mild acne where resistance to antibiotics or intolerance to retinoids is a factor. International dermatology guidelines (including those of the European Dermatology Forum) recognize Azelaic Acid 20% as an evidence-based option for acne, with a favourable safety and tolerability profile and suitability for long-term maintenance. It is particularly recommended for adult women with hormonally influenced acne, in whom concerns about antibiotic resistance and retinoid teratogenicity make Azelaic Acid an ideal choice.
For papulopustular rosacea — characterized by inflammatory acne-like papules and pustules on a background of facial redness — Azelaic Acid 20% is considered a first-line treatment in multiple clinical guidelines. It significantly reduces the inflammatory lesion count, with visible improvement typically observed after 12 weeks of twice-daily application. In the management of melasma and post-inflammatory hyperpigmentation, the 20% concentration provides a more pronounced, faster brightening effect than the 10% concentration, making it preferred for patients with moderate-to-severe pigmentation concerns.
Comparing Aziderm Cream 20% and Skinoren 20%: Brand vs Generic Differences
Aziderm Cream 20% and Finacea 20%, both contain azelaic acid and are used to treat acne, pigmentation, and rosacea by reducing bacteria, inflammation, and clogged pores. Finacea is a branded formulation widely recognized in international markets, while Aziderm Cream 20% is a more affordable generic alternative commonly available in India. Both products provide similar therapeutic effects because they contain the same active ingredient at the same strength, but they may differ in texture, inactive ingredients, packaging, and manufacturer standards. Some users may notice differences in skin absorption, irritation levels, or overall skin feel. Aziderm is often preferred for cost-effective long-term treatment, whereas Finacea may be chosen for brand preference or dermatologist recommendation. Consistent use under medical guidance is important for achieving the best results with either product.
Related strengths and products: Patients beginning Azelaic Acid therapy may prefer to start with Aziderm Cream 10% 15g to assess skin tolerance before escalating to the 20% strength. For combination acne management, Acnesol Gel 1% (Clindamycin topical antibiotic) or Adaferin Gel 0.1% (Adapalene retinoid) can be used alongside Azelaic Acid under dermatologist guidance to address different components of acne pathogenesis.
Key Benefits of Aziderm Cream 20%
Aziderm Cream 20% delivers the highest clinically validated topical dose of Azelaic Acid, maximizing its triple-action effect against acne, rosacea, and pigmentation simultaneously. As a non-antibiotic antibacterial, it eliminates the risk of inducing resistance in acne-causing bacteria — a growing concern with prolonged topical antibiotic use — and can be used continuously for months to years without this limitation. Unlike topical retinoids, it is not photosensitizing, allowing both morning and evening application without mandatory sun avoidance, though daily SPF use remains recommended for patients managing hyperpigmentation. It is safe for use in adult women who are pregnant or considering pregnancy — a significant advantage over retinoids, which are teratogenic. Its selective action on abnormally pigmented melanocytes means it lightens dark spots without bleaching normally pigmented surrounding skin, making it safe and effective for patients with darker skin tones who are prone to both acne and post-inflammatory hyperpigmentation.
Usage warnings and precautionary advice for using Azelaic Acid 20%
Aziderm Cream 20% is for external use only. Avoid application to the eyes, broken skin, or mucous membranes. An initial burning or stinging sensation is common and typically resolves within the first two to four weeks of use; if it is severe or persistent, consider starting with the 10% strength and escalating after tolerance is established. Patients with known hypersensitivity to Azelaic Acid or to any excipient in the formulation should not use this product. Although Azelaic Acid is considered Pregnancy Category B and is used in pregnancy for rosacea management in some clinical settings, use during pregnancy or lactation should be reviewed with a physician. Avoid contact with dyed fabrics such as clothing and bed linen, as Azelaic Acid may cause minor staining.
Side effects of Azelaic Acid 20%
The side effects of Aziderm Cream 20% are primarily localized to the application site. Burning, stinging, tingling, and itching are the most commonly reported effects and are dose-related — they are more frequent at the 20% concentration than at 10%, particularly in the first few weeks of treatment. Skin dryness, scaling, and mild peeling may also occur, especially in patients with already sensitive or dry skin. These effects generally resolve within a month of consistent use as the skin adapts. Expected therapeutic lightening of hyperpigmented areas should not be confused with a side effect. Rare cases of allergic contact dermatitis have been reported, presenting as widespread redness, swelling, and urticaria beyond the application site. Hypopigmentation at the application site, while rare at standard concentrations, has been reported in patients with darker skin tones who use high-strength formulations for extended periods.
Benefits of Buying Aziderm Cream 20% Online
AllDayChemist provides genuine Glenmark-manufactured Aziderm Cream 20% at highly competitive prices, offering patients with long-term acne, rosacea, or pigmentation concerns a cost-effective and reliable supply channel. The discreet packaging and international delivery available through AllDayChemist make it easy to maintain consistent treatment — critical for conditions that require months of continuous topical therapy. Check a wide dermatology catalogue, including moisturizers, SPF creams, and combination acne treatments, all in one place.
Proper dosage and usage guide of Azelaic Acid 20% Cream
Aziderm Cream 20% should be applied twice daily — morning and evening — to clean, dry skin. A thin layer of cream should be gently massaged into the affected areas of the face or body until fully absorbed; avoid the eye area, nostrils, and mouth. Wash hands thoroughly after application. In patients who experience significant burning or dryness on initiation, the frequency can be reduced to once daily for the first two weeks before advancing to twice daily. Improvement in acne is typically visible after four to eight weeks, while results for pigmentation and rosacea may take eight to twelve weeks of consistent use. Daily SPF 30+ sunscreen use in the morning is strongly recommended for optimal pigmentation outcomes. Store at room temperature below 25°C, away from light and moisture.
What condition does Aziderm Cream 20 % (15gm) treat, and how is it used by doctors?
Aziderm Cream treats acne by reducing the bacteria and inflammation that cause spots and breakouts. It contains azelaic acid, which works to unclog pores and calm irritated skin. Doctors prescribe it as a topical cream that you apply directly to affected areas of your face or body. It is often used alongside other acne treatments or as a standalone option for mild to moderate acne. Treatment typically takes several weeks to show visible improvement.
Who should use Aziderm Cream 20 % (15gm), and who should not use it?
Aziderm Cream is suitable for teenagers and adults with acne who need a gentle, effective treatment. Do not use this cream if you are allergic to azelaic acid or any other ingredient. Tell your doctor if you are pregnant, breastfeeding, or have very sensitive skin. People with severe rosacea or certain skin conditions should check with their doctor first. Always inform your doctor about all skin products you currently use.
How often should I apply this cream?
Apply Aziderm Cream twice daily, once in the morning and once at night. First, wash your face gently with mild soap and water, then pat your skin dry completely. Apply a thin layer of cream to the affected areas and rub it in gently. Do not apply to broken or severely irritated skin. Consistency is important for best results, so try to apply it at the same times each day.
What should I do if I miss an application?
If you forget to apply the cream, simply apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Never apply double the amount to make up for a missed application. Missing one or two doses will not harm your skin, but staying consistent with your routine helps you achieve better results faster.
What should I do if this cream causes stinging, redness, or irritation?
Some stinging or mild redness is normal when you first start using azelaic acid cream, especially in the first week. These effects usually fade as your skin adjusts. If irritation becomes severe or does not improve within two weeks, reduce application to once daily instead of twice. If stinging, severe redness, or swelling continues, stop using the cream and contact your doctor. Always use a gentle moisturizer to help calm your skin.
Does using more cream than directed give better or faster results?
No, using more cream than directed will not speed up results and may cause unnecessary skin irritation. Too much product can lead to redness, dryness, and discomfort. Stick to the recommended amount, which is a thin layer applied twice daily. Your skin needs time to adjust and improve, which typically takes four to twelve weeks. Patience and consistent use of the correct amount will give you the best outcome.
How well does Aziderm Cream 20 % (15gm) work for Acne, and what do studies show?
Clinical studies show that azelaic acid is effective for treating mild to moderate acne and rosacea. Most patients see noticeable improvement in acne lesions, redness, and texture within four to twelve weeks of regular use. It works particularly well for people with sensitive skin who cannot tolerate stronger acne medicines. Success rates improve when combined with a good skincare routine and sun protection. Individual results vary depending on acne severity and skin type.
What are the common and serious side effects of Aziderm Cream 20 % (15gm), and what should I do if they happen?
Common side effects include mild stinging, itching, redness, and dryness, especially during the first few weeks. These usually fade as your skin adjusts. Serious side effects are rare but may include severe allergic reactions with swelling, difficulty breathing, or severe skin irritation. If you develop a rash, hives, or difficulty breathing, stop using the cream immediately and seek emergency help. Report any unusual reactions to your doctor promptly.
What is the difference between the generic Aziderm Cream 20 % (15gm) and the brand Finacea cream?
Aziderm Cream contains the same active ingredient and strength as Finacea cream 20%. Both contain twenty percent azelaic acid and work identically to treat acne. The main difference is price, as Aziderm is a generic alternative that costs significantly less. Generic medicines meet the same safety and quality standards as brand-name products. You will receive the same therapeutic benefits from either product.
Can I use Aziderm Cream 20 % (15gm) long-term, or is it only meant for short-term use?
Aziderm Cream is safe for long-term use and is often used for several months or longer to maintain clear skin. Many patients continue using it even after their acne improves to prevent breakouts from returning. Long-term use does not cause dependence or reduced effectiveness. However, continue to follow your doctor's instructions and have regular check-ins to ensure the treatment remains effective for your skin. Your doctor may adjust your routine as your skin improves.
How does Aziderm Cream 20 % (15gm) compare to Persol gel (benzoyl peroxide), and when would a doctor choose one over the other?
Azelaic acid and benzoyl peroxide both treat acne, but work differently. Benzoyl peroxide kills bacteria quickly and is stronger, making it ideal for severe acne. Azelaic acid is gentler and works by reducing bacteria and inflammation, making it better for sensitive skin and rosacea. Doctors choose azelaic acid for patients who cannot tolerate benzoyl peroxide or who have red, irritated skin. Some patients benefit from using both products together.
Can I use makeup while using Aziderm Cream 20%?
Yes, makeup can generally be used while using Aziderm Cream. It is advisable to choose non-comedogenic cosmetics that do not clog pores. Allow the cream to absorb fully before applying makeup. Properly removing makeup at the end of the day is equally important for preventing pore blockage and maintaining skin health. If you notice increased irritation after using certain cosmetic products, consider switching to gentler alternatives and consult your healthcare provider if needed.
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