Available Dosages
| SKU: | 1026 |
|---|---|
| Active Ingredient: | Spironolactone |
| Manufacturer: | RPG Life Science, India |
Buy Aldactone 100 mg (Spironolactone) Online
Aldactone 100 mg is a powerful, multi-purpose medication that effectively treats high blood pressure, fluid retention, and hormonal imbalances. Its potassium-sparing action makes it safer for long-term use compared to traditional diuretics. Looking to buy Aldactone 100 mg online at the best price? Aldactone is a trusted prescription medication used worldwide to help remove excess fluid without causing potassium loss, making it safer for long-term use than many traditional water pills. Order Aldactone 100 mg today for safe, effective, doctor-recommended treatment, discreetly delivered to your doorstep.
What is Aldactone 100 mg?
Aldactone 100mg is for fast, effective relief for blood pressure & fluid retention. It has spironolactone, an aldosterone antagonist that helps balance fluids and electrolytes in the body. It blocks the effects of aldosterone, a hormone responsible for sodium and water retention. Unlike other diuretics, Aldactone prevents potassium loss, reduces swelling and fluid buildup, and lowers blood pressure naturally. It is widely prescribed for both cardiovascular and hormonal conditions, making it a versatile and effective treatment option. Aldactone 100mg in India is commonly manufactured by RPG Life Science.
Spironolactone: The working mechanism
Aldactone 100 mg contains spironolactone, a potassium-sparing diuretic that acts by blocking aldosterone receptors in the kidneys. Aldosterone normally signals the body to retain sodium and water while excreting potassium. By inhibiting this hormone, spironolactone promotes the excretion of excess fluid and sodium in the urine while preserving potassium levels. This dual action helps reduce blood pressure, relieve swelling, and support heart function. Additionally, it has mild anti-androgen effects, making it useful in managing hormonal conditions such as acne and PCOS. Its targeted mechanism ensures effective fluid control without causing a significant electrolyte imbalance when used appropriately.
Brand vs generic– What's the difference?
The difference between the brand-name Aldactone 100 mg and the generic Aldactone 100 mg mainly lies in branding, cost, and formulation consistency rather than in effectiveness. Both contain the same active ingredient and work in the same way by blocking aldosterone, reducing fluid retention, managing blood pressure, and treating hormonal conditions such as acne or PCOS.
Pfizer manufacture Aldactone 100mg in the USA, and RPG Life Sciences manufactures it in India. Overall, both are therapeutically equivalent, and the choice usually depends on budget, brand preference, and individual response.
Explore other options for heart and blood pressure medicine for better comparison.
Aldactone 100 mg uses (why doctors prescribe it)
- High blood pressure: Aldactone helps control blood pressure by removing excess sodium and water, reducing strain on the heart.
- Fluid retention: Used to treat swelling caused by liver cirrhosis and kidney disease. Heart failure management and survival rates improve when used alongside other medications.
- Hormonal acne treatment: Spironolactone reduces androgen hormones, decreasing oil production and helping clear acne.
- Polycystic ovary syndrome (PCOS): Helps regulate hormones, improving irregular periods, excess facial hair, acne, and hyperaldosteronism, and treats conditions caused by excess aldosterone production.
How does Aldactone 100 mg work?
Aldactone works by blocking aldosterone, which normally causes the body to retain sodium and water. As a result, excess fluid is removed through urine, blood pressure decreases, potassium levels are preserved, and swelling reduces significantly. This targeted mechanism makes it one of the most effective potassium-sparing diuretics available.
Key benefits of Aldactone 100 mg
- Helps lower high blood pressure
- Reduces fluid retention and swelling
- Supports the treatment of heart failure
- Effective for hormonal acne in women
- Helps manage PCOS symptoms
- Maintains healthy potassium levels
- Suitable for long-term use under medical supervision
Important safety information about spironolactone
Avoid this medicine if you have high potassium levels, severe kidney disease, or are allergic to spironolactone. Use cautiously if you are pregnant or breastfeeding, take blood pressure medicines, or use potassium supplements. Inform your doctor about existing medicines or health supplements you may be taking.
Drug interactions: Aldactone may interact with ACE inhibitors, ARBs, NSAIDs, and other diuretics
Spironolactone 100mg side effects
Most side effects are mild and temporary. Common side effects are dizziness, headache, increased urination, nausea, hormonal effects, breast tenderness, menstrual irregularities, and reduced libido. Serious side effects include high potassium levels, irregular heartbeat and severe dehydration. Seek medical help if severe symptoms occur.
Purchasing Aldactone 100 mg online?
Buying Aldactone 100 mg online from AllDayChemist (ADC) offers a convenient and cost-effective way to access this widely prescribed medication. Ordering online lets you compare prices, choose quantities, and enjoy discreet home delivery. Ensure you follow prescription guidelines and verify the pharmacy's authenticity before purchasing. With secure payment options and reliable shipping, ADC makes it easy to manage long-term treatment while saving time and money. Limited stock available, order now to avoid delays. Prices may vary depending on quantity and supplier. Bulk purchases often come with additional discounts. Buying larger packs can significantly reduce the cost per tablet.
Spironolactone 100 mg dosage guide
Recommended dosage for hypertension is 25–100 mg daily. To treat oedema, 100 mg daily (adjusted as needed). For hormonal conditions, it is to be used as prescribed. Take with food for better absorption. Use at the same time daily. Follow your doctor's instructions strictly. Do not self-adjust your dosage.
What is Aldactone 100mg used for?
Aldactone 100mg contains spironolactone 100mg, a potassium-sparing diuretic and aldosterone antagonist. It is used to treat oedema and fluid retention associated with heart failure, liver cirrhosis, and nephrotic syndrome; primary hyperaldosteronism; essential hypertension; and as adjunct therapy in severe heart failure to reduce mortality. Off-label uses include polycystic ovary syndrome (PCOS), hirsutism, female-pattern hair loss, and acne — conditions driven by androgen excess. Spironolactone competitively blocks aldosterone receptors in the distal nephron, promoting Sodiumium excretion while retaining potassium. It is widely prescribed in the USA, UK, and Australia.
How does spironolactone in Aldactone 100mg work?
Spironolactone in Aldactone 100mg works by competitively blocking mineralocorticoid (aldosterone) receptors in the kidney. Aldosterone normally promotes Sodiumium and water retention while excreting potassium. By blocking these receptors, spironolactone reverses these effects, increasing Sodiumium and water excretion (diuresis) while reducing potassium loss. In heart failure, spironolactone's cardioprotective effect goes beyond diuresis — it also blocks aldosterone's fibrotic effects on the myocardium, reducing cardiac remodelling and improving survival. Its anti-androgenic properties (blocking androgen receptors) underlie its use in PCOS, hirsutism, and acne.
What is the usual dose of Aldactone 100mg for heart failure?
In heart failure, spironolactone dosing starts low (typically 25mg once daily) and is titrated upward based on clinical response and potassium levels. The 100mg dose represents a higher therapeutic dose used when lower doses are insufficient for oedema control or when primary hyperaldosteronism requires more complete aldosterone blockade. In the landmark RALES trial, spironolactone 25mg daily significantly reduced mortality in severe heart failure. The 100mg dose is typically reserved for oedema states, hyperaldosteronism treatment, or conditions requiring more aggressive aldosterone blockade. Always follow the dose prescribed by your cardiologist or physician — serum potassium monitoring is essential at any dose.
Should Aldactone 100mg be taken with food?
Aldactone 100mg can be taken with or without food. However, taking spironolactone with a meal containing food (particularly with fat-containing food) can increase its absorption by up to 30%, potentially enhancing its diuretic effect. Consistency of administration — either always with food or always without — is more important than the specific timing, as it ensures predictable drug levels day to day. For patients who experience gastrointestinal discomfort with spironolactone, taking it with food helps reduce nausea. The tablet should be swallowed whole with a glass of water. Take it at the same time each day to maintain steady-state drug levels and consistent diuretic effect.
What are the main risks of taking Aldactone 100mg?
The most significant risk of Aldactone 100mg is hyperkalaemia (elevated blood potassium). By retaining potassium, spironolactone can cause dangerous potassium accumulation — particularly in patients with renal impairment, diabetes, or those taking ACE inhibitors, ARBs, potassium supplements, or other potassium-sparing diuretics. Severe hyperkalaemia causes cardiac arrhythmias and can be life-threatening. Serum electrolytes and renal function must be monitored regularly. Other risks include dehydration, hyponatraemia, gynecomastia in men (breast tissue growth from anti-androgenic effect), menstrual irregularities, and dizziness. The 100mg dose carries proportionally higher risk of these effects than lower doses.
Can Aldactone 100mg be taken with ACE inhibitors or ARBs?
Aldactone 100mg combined with ACE inhibitors (e.g., ramipril, lisinopril) or ARBs (e.g., candesartan, irbesartan) significantly increases the risk of hyperkalaemia, as all three agents reduce renal potassium excretion through different mechanisms. The combination is used in heart failure (evidence supports spironolactone + ACE inhibitor), but requires rigorous electrolyte monitoring — serum potassium and creatinine should be checked within 1 week of any dose change and at least every 3 months thereafter. Potassium levels above 5.5 mmol/L should prompt dose reduction or temporary discontinuation of spironolactone. Never add potassium supplements to this combination without explicit medical guidance.
How does Aldactone 100mg compare to eplerenone for heart failure?
Aldactone 100mg (spironolactone) and eplerenone are both mineralocorticoid receptor antagonists used in heart failure. Key differences: spironolactone is non-selective — it also blocks androgen and progesterone receptors, causing gynecomastia, breast tenderness, and menstrual irregularities. Eplerenone is more selective for mineralocorticoid receptors, with significantly lower rates of hormonal side effects. The EPHESUS and EMPHASIS-HF trials established eplerenone's cardiovascular mortality benefit similar to spironolactone. Spironolactone remains first-line due to lower cost and decades of clinical evidence. Eplerenone is preferred when spironolactone causes unacceptable anti-androgenic side effects, particularly in men with gynecomastia.
Is Aldactone 100mg safe for women with PCOS or hirsutism?
Aldactone 100mg is widely used off-label in women for polycystic ovary syndrome (PCOS), hirsutism (excess hair growth), female-pattern hair loss, and acne. Its anti-androgenic effect — blocking androgen receptors in hair follicles and sebaceous glands — reduces androgen-driven symptoms. Studies show spironolactone 100–200mg/day significantly reduces hirsutism and acne scores in women with PCOS over 6–12 months. Women of childbearing potential must use reliable contraception, as spironolactone can cause feminisation of a male fetus. It is not used in pregnancy. At 100mg, menstrual irregularities and breast tenderness are common. Serum potassium monitoring applies equally in this indication.
Can I buy Aldactone 100mg from AllDayChemist?
Yes, Aldactone 100mg is available at AllDayChemist, a trusted licensed pharmacy operating since 2002 and serving most of the countries. AllDayChemist sources authentic spironolactone directly from licensed manufacturers at competitive prices compared to branded Aldactone at retail pharmacies in the USA, UK, and Australia. Patients managing heart failure, oedema, hyperaldosteronism, or hormonal conditions benefit from AllDayChemist's affordable pricing, discreet packaging, and worldwide tracked delivery. Spironolactone at 100mg is a prescription medication — obtain medical clearance and regular monitoring before initiating therapy and before ordering.
Is AllDayChemist a trustworthy source for Aldactone 100mg?
AllDayChemist has built a two-decade reputation as a licensed, reliable pharmacy since 2002, supplying authentic medications to patients in most of the countries including the USA, UK, and Australia. Aldactone 100mg sourced from AllDayChemist comes from verified pharmaceutical manufacturers, ensuring product authenticity and potency — critical for medications like spironolactone where consistent dosing affects potassium balance and cardiovascular outcomes. Discreet packaging, worldwide tracked shipping, and competitive pricing combine to make AllDayChemist a practical source for ongoing heart failure or hormonal management medications.
What are the side effects of Aldactone 100mg?
Side effects of Aldactone 100mg include hyperkalaemia (the most dangerous — monitor potassium levels), hyponatraemia, dehydration, dizziness, and hypotension. Anti-androgenic effects include gynecomastia and breast tenderness in men, menstrual irregularities and breast tenderness in women, and decreased libido. Gastrointestinal effects include nausea, vomiting, stomach cramps, and diarrhoea. Drowsiness and confusion can occur at higher doses or in elderly patients. Rare adverse effects include agranulocytosis, hepatotoxicity, and severe skin reactions. The 100mg dose carries a higher risk of both hyperkalaemia and anti-androgenic side effects than the 25mg dose. Regular electrolyte monitoring is mandatory.
Can Aldactone 100mg cause high potassium levels?
Yes — hyperkalaemia (elevated serum potassium) is the most clinically significant risk of Aldactone 100mg. Spironolactone reduces renal potassium excretion by blocking aldosterone's action in the collecting tubule. At 100mg daily, this effect is substantial. Risk is highest in patients with renal impairment, diabetes (which impairs transcellular potassium shift), elderly patients, and those taking concurrent ACE inhibitors, ARBs, NSAIDs, heparin, or potassium supplements. Serum potassium above 5.5 mmol/L requires dose reduction; above 6.0 mmol/L requires immediate cessation and urgent medical review. Patients on Aldactone 100mg should avoid high-potassium foods (bananas, oranges, potatoes) in excess and never self-supplement potassium.
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