Obelit 120 mg contains the active ingredient Orlistat, an anti-obesity medicine approved by the US Food and Drug Administration (FDA). It is indicated for the treatment of patients with obesity who have a body mass index (BMI) of 30 kg/m² or higher. Obelit 120 is prescribed for patients with a BMI greater than 27kg/m2 and the presence of risk factors, including diabetes, hypertension, and dyslipidemia. It can also be given to individuals who are seeking to mitigate the risk of weight regain following previous weight loss efforts.
The maximum benefit of Obelit 120 mg is obtained when this medication is combined with regular exercise and a balanced diet. Weight reduction typically starts within 14 days of starting this medication. However, significant weight loss is observed after the use of Orlistat exceeds two months. Reports of clinical trials suggest that weight loss in patients by the end of six months of Obelit 120 use is approximately 5.6 kg. Orlistat also causes a significant reduction in BMI, waist circumference, total cholesterol and low-density lipoprotein levels.
In a clinical trial, this weight loss drug has shown a significant effect in reducing the incidence of diabetes among patients with impaired glucose tolerance. The American Academy of Paediatrics guidelines suggest Orlistat for the management of obesity in children aged 12 and older.
How does Obelit work?
Obelit contains the active ingredient Orlistat, which promotes weight loss by decreasing the amount of dietary fat absorbed in the intestines. It reversibly inhibits gastric and pancreatic lipases within the gut. Lipase is an enzyme present in the digestive tract that helps transform dietary fat into smaller components, allowing it to be stored or used for energy.
Orlistat works by blocking the activity of lipases. When you take this weight loss medicine with a meal, about 25% of the fat isn’t broken down. The fat is transferred through bowel movements. Research also concluded that Orlistat helps improve cholesterol and blood pressure levels, thereby enhancing blood sugar control. Research studies therefore demonstrate that Orlistat can improve weight loss if used in combination with behavioural and lifestyle changes.
An effective fat-blocking agent
Due to its potential to block fat absorption, Obelit may also inhibit the absorption of fat-soluble vitamins. Therefore, it is recommended to take a multivitamin daily to inhibit the absorption of fat. This weight loss medicine offers a new treatment approach for weight loss and maintenance. Research data from numerous clinical studies suggest that Orlistat may benefit patients with comorbid conditions associated with obesity, such as diabetes and hyperlipidemia (high cholesterol). However, further research is needed to completely establish the long-term safety and benefits of Orlistat 120 mg. The medicine should be considered a useful adjunctive treatment for weight loss and maintenance in obese patients committed to lifestyle interventions, including diet, exercise, and behavioural changes. You can buy Obelit online at the best price.
Administration methods
Obelit side effects need to be discussed before getting this medicine. The recommended Obelit prescription dosage is 120 mg and is available in capsule form, to be taken orally three times daily. The usage is recommended during or within one hour after consuming a high-fat meal. The dosage of more than 120 mg does not have any additional beneficial effects. Along with the use of Obelit, patients are recommended to follow a nutritionally balanced, low-calorie diet that carries less than 30% of calories from fat. If the patient skips a meal, they are not advised to take Orlistat. If the patient skips the dose of Orlistat and it has been more than two hours since eating a meal, then the patient can skip that dose because most of the fat is absorbed by then, and the medication would not work effectively.
Since this medicine reduces the absorption of fat-soluble vitamins, patients are advised to take multivitamin supplements regularly to ensure adequate intake of these vitamins. Multivitamin supplements should be taken at least two hours after administering Obelit 120 mg.
Specific patient populations
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- Hepatic insufficiency: Caution should be exercised when prescribing Obelit to patients with abnormal liver function tests and obstructed bile ducts.
- Renal insufficiency: Orlistat is considered safe for use in patients with kidney impairment.
- Pregnancy considerations: The use of Orlistat is contraindicated in pregnant women. Patients undergoing Orlsitat treatment should use a reliable method of contraception. It is recommended that the limiting gestational weight gain at the time of pregnancy is related to reduced risk of emergency caesarean delivery, macrosomia, and gestational diabetes. Behavioural changes are preferred over medicinal treatment for managing gestational weight.
- Breastfeeding considerations: Obelit is minimally observed in the body; therefore, only a small amount is detected in breast milk. However, the medication restricts the absorption of fat-soluble vitamins, so breastfeeding women should take a multivitamin supplement containing these fat-soluble vitamins. Infants are unlikely to absorb the medication in a quantity that would have a negative effect on them. However, the medication is often labelled with caution when it is used while breastfeeding, and also, guidelines do not recommend this medication while breastfeeding.
- Children: Orlistat has received FDA approval for the long-term treatment of obesity in children aged 12 years and older. However, the safety and effectiveness of the medicine have not been established in children under twelve years of age.
- Elderly patients: Research studies have demonstrated the effectiveness of Orlistat in older patients. The drug is FDA-approved for use in older patients with obesity. It effectively manages obesity by reversibly inhibiting gastric and pancreatic lipases within the gut. These lipases are crucial for the digestion of dietary fat by breaking down triglycerides, fatty acids, and monoglycerides that are easily absorbable.
Conclusion
Orlistat (Obelit 120) is currently the most commonly prescribed anti-obesity medication; however, considerable variability in its effectiveness remains. It is often less effective due to poor adherence to dietary and exercise recommendations. However, its effectiveness is often compromised by poor adherence to suggested lifestyle modifications and adverse effects like steatorrhea (presence of excessive fat in the faeces). Ensure to use Obelit 120 for weight loss under a doctor’s supervision only.
