Tenofovir Disoproxil Fumarate is a medicine used to treat hepatitis B in people 12 years of age and older. The medication is also recommended for use with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients two years of age and older. However, it will not cure hepatitis B virus, but lower the amount of hepatitis B virus in the patient’s body. The drug does this by reducing the ability of the virus to multiply in the body. Tenvir 300 mg is the most popular brand that contains Tenofovir Disoproxil Fumarate.
The active component improves the condition of your liver. It is a key component of many antiretroviral therapy regimens, despite concerns about renal and bone toxicity with long-term use. It is to notify that the drug does not reduce the risk of passing the virus to others.
Tenofovir Disopoxil Fumarate, sold under the trade name Tenvir 300 mg is a nucleotide reverse transcriptase inhibitor (NRTIs), which works by stopping the virus from multiplying in the body. Tenvir EM 300/200mg is also available to prevent HIV infection, thereby reducing the amount of virus in the bloodstream of an infected individual. The products include emtricitabine along with tenofovir to lower the amount of virus in the blood.
What are the Benefits of using Tenofovir Disoproxil Fumarate?
Here are given the advantages of using an antiretroviral agent like Tenofovir or Tenvir 300 mg:
- Reduce the amount of HIV and HBV virus in the body
- Improves liver health
- Safe and effective treatment to treat chronic hepatitis B in children below the age of 12 years.
- Reduces the risk of transferring the HBV virus to others
- One tablet a day, every day is required to stop the progression of the disease.
What is the correct dosage?
For adults and children, the recommended dose is 300 mg once daily. Patients can take the tablets before or after consuming food.
The dose for the treatment of HIV 1 in patients from two to less than 12 years of age is decided according to the weight of the patient. If your kid has HIV-1 or HBV infection, consult your healthcare specialist for an appropriate dose for your children.
Are there any possible side effects?
- In HIV infected adults- Most commonly reported adverse reactions are nausea, headache, rash, pain, depression, diarrhea, and asthenia.
- In patients with hepatitis B with the compensated liver disease- Nausea was one of the commonly reported side effects of the antiretroviral agent.
- In pediatrics patients- headache, diarrhea, asthenia, depression, pain, and rash.
- In patients with hepatitis B virus with the decompensated liver disease- Most common side effects were insomnia, dizziness, pyrexia, abdominal pain, vomiting, nausea, and pruritus.
What are the warnings associated with the antiretroviral agent?
- Tenofovir disoproxil fumarate can interact with certain foods. In some cases, this may be harmful, and your health care specialist may advise you to avoid certain foods during the treatment.
- Your anti-retroviral medication may affect the way other medicines work, and other drugs may affect the working of Tenofovir. A patient taking Tenofovir to prevent the progression of the HIV of HBV virus is not supposed to take atazanavir, didanosine, lopinavir with ritonavir.
- Patients who are at high risk of developing renal dysfunction should assess for creatinine clearance, urine glucose, and urine protein before initiating the treatment.